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Volume 13, Issue 2

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 13, Issue 2 (2017)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 13, Issue 2 (2017)

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Editorial

Judging the value of ‘liver-on-a-chip’ devices for prediction of toxicity

Viktoriia Starokozhko & Geny M. M. Groothuis

Pages: 125-128

Published online: 18 Oct 2016

First Page PreviewforJudging the value of ‘liver-on-a-chip’ devices for prediction of toxicity | Full Text | References | PDF (320.1 KB)

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Review

Assessing the viability of long-acting β₂-agonists in paediatric asthma patients: a pharmacokinetic/pharmacodynamic perspective

Maria Gabriella Matera, Barbara Rinaldi, Luigino Calzetta & Mario Cazzola

Pages: 129-136

Published online: 14 Sep 2016

AbstractforAssessing the viability of long-acting β₂-agonists in paediatric asthma patients: a pharmacokinetic/pharmacodynamic perspective | Full Text | References | PDF (589.2 KB)

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Review

Upgrading HepG2 cells with adenoviral vectors that encode drug-metabolizing enzymes: application for drug hepatotoxicity testing

M. José Gómez-Lechón, Laia Tolosa & M. Teresa Donato

Pages: 137-148

Published online: 27 Sep 2016

AbstractforUpgrading HepG2 cells with adenoviral vectors that encode drug-metabolizing enzymes: application for drug hepatotoxicity testing | Full Text | References | PDF (1.1 MB)

410 Views
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Review

Molecular basis of aromatase inhibitor associated arthralgia: known and potential candidate genes and associated biomarkers

Adrienne E. Borrie & Richard B. Kim

Pages: 149-156

Published online: 20 Sep 2016

AbstractforMolecular basis of aromatase inhibitor associated arthralgia: known and potential candidate genes and associated biomarkers | Full Text | References | PDF (772.3 KB)

350 Views
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Review

The amikacin research program: a stepwise approach to validate dosing regimens in neonates

Anne Smits, Aida Kulo, John van den Anker & Karel Allegaert

Pages: 157-166

Published online: 21 Sep 2016

AbstractforThe amikacin research program: a stepwise approach to validate dosing regimens in neonates | Full Text | References | PDF (935.6 KB)

589 Views
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Review

Drug metabolism by flavin-containing monooxygenases of human and mouse

Ian R. Phillips & Elizabeth A. Shephard

Pages: 167-181

Published online: 29 Sep 2016

AbstractforDrug metabolism by flavin-containing monooxygenases of human and mouse | Full Text | References | PDF (1.2 MB)

1147 Views
75 CrossRef citations
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Review

Pharmacodynamics, pharmacokinetics and clinical efficacy of phosphodiesterase-5 inhibitors

Jeong Hee Hong, Young Suk Kwon & Isaac Yi Kim

Pages: 183-192

Published online: 21 Oct 2016

AbstractforPharmacodynamics, pharmacokinetics and clinical efficacy of phosphodiesterase-5 inhibitors | Full Text | References | PDF (766 KB)

373 Views
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Review

Drug-induced steatohepatitis

Ajit Dash, Robert A. Figler, Arun J. Sanyal & Brian R. Wamhoff

Pages: 193-204

Published online: 27 Oct 2016

AbstractforDrug-induced steatohepatitis | Full Text | References | PDF (1.5 MB)

638 Views
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Drug Evaluation

Article

Pharmacokinetic drug evaluation of anacetrapib for the treatment of dyslipidemia

Claudio Borghi & Arrigo F. G. Cicero

Pages: 205-209

Published online: 04 Dec 2016

AbstractforPharmacokinetic drug evaluation of anacetrapib for the treatment of dyslipidemia | Full Text | References | PDF (437.9 KB)

286 Views
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Article

Evaluation of the pharmacokinetics, pharmacodynamics and clinical efficacy of empagliflozin for the treatment of type 2 diabetes

Brian Tomlinson, Miao Hu, Yuzhen Zhang, Paul Chan & Zhong-Min Liu

Pages: 211-223

Published online: 20 Nov 2016

AbstractforEvaluation of the pharmacokinetics, pharmacodynamics and clinical efficacy of empagliflozin for the treatment of type 2 diabetes | Full Text | References | PDF (1.4 MB)

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Article

Pharmacokinetic drug evaluation of atezolizumab for the treatment of locally advanced or metastatic urothelial carcinoma

Rutveej Patel, Megan Bock, Charles F. Polotti & Sammy Elsamra

Pages: 225-232

Published online: 11 Jan 2017

AbstractforPharmacokinetic drug evaluation of atezolizumab for the treatment of locally advanced or metastatic urothelial carcinoma | Full Text | References | PDF (701.8 KB)

798 Views
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Perspective

Article

Use of monoamine oxidase inhibitors in chronic neurodegeneration

Peter Riederer & Thomas Müller

Pages: 233-240

Published online: 01 Jan 2017

AbstractforUse of monoamine oxidase inhibitors in chronic neurodegeneration | Full Text | References | PDF (700.4 KB)

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Expert Opinion on Drug Metabolism & Toxicology (Vol.13, Iss.2, 2017)

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