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Volume 2, Issue 4

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 2, Issue 4 (2006)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 2, Issue 4 (2006)

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Editorial

Article

The use of hepatotoxic signals to predict the safety of peroxisome proliferator-activated receptor agonists

Kenneth L Hastings

Pages: 489-492

Published online: 21 Jul 2006

First Page PreviewforThe use of hepatotoxic signals to predict the safety of peroxisome proliferator-activated receptor agonists | Full Text | References | PDF (59.2 KB)

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Review

Article

Role of innate immunity in acetaminophen-induced hepatotoxicity

Zhang-Xu Liu & Neil Kaplowitz

Pages: 493-503

Published online: 21 Jul 2006

AbstractforRole of innate immunity in acetaminophen-induced hepatotoxicity | Full Text | References | PDF (143.6 KB)

485 Views
99 CrossRef citations
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Article

Drugdrug interactions involving membrane transporters in the human kidney

Meng Li, Gail D Anderson & Joanne Wang

Pages: 505-532

Published online: 21 Jul 2006

AbstractforDrugdrug interactions involving membrane transporters in the human kidney | Full Text | References | PDF (239.7 KB)

475 Views
68 CrossRef citations
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Article

Pharmacokinetic interactions between HIV antiretroviral therapy and drugs used to treat opioid dependence

Benjamin Maas, Thomas Kerr, Nadia Fairbairn, Julio Montaner & Evan Wood

Pages: 533-543

Published online: 21 Jul 2006

AbstractforPharmacokinetic interactions between HIV antiretroviral therapy and drugs used to treat opioid dependence | Full Text | References | PDF (119.3 KB)

121 Views
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Article

Structure-based methods for the prediction of drug metabolism

Judith C Madden & Mark TD Cronin

Pages: 545-557

Published online: 21 Jul 2006

AbstractforStructure-based methods for the prediction of drug metabolism | Full Text | References | PDF (129.4 KB)

177 Views
31 CrossRef citations
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Article

The role of amine oxidases in xenobiotic metabolism

Bin Gong & Paul J Boor

Pages: 559-571

Published online: 21 Jul 2006

AbstractforThe role of amine oxidases in xenobiotic metabolism | Full Text | References | PDF (186.1 KB)

303 Views
34 CrossRef citations
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Article

Current views on the fundamental mechanisms of cytochrome P450 allosterism

William M Atkins

Pages: 573-579

Published online: 21 Jul 2006

AbstractforCurrent views on the fundamental mechanisms of cytochrome P450 allosterism | Full Text | References | PDF (97.5 KB)

153 Views
40 CrossRef citations
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Article

Recent progress in cytochrome P450 enzyme electrochemistry

Barry D Fleming, Daniel L Johnson, Alan M Bond & Lisandra L Martin

Pages: 581-589

Published online: 21 Jul 2006

AbstractforRecent progress in cytochrome P450 enzyme electrochemistry | Full Text | References | PDF (128.2 KB)

297 Views
36 CrossRef citations
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Article

The road map to oral bioavailability: an industrial perspective

V Hayden Thomas, Shobha Bhattachar, Linda Hitchingham, Philip Zocharski, Maryanne Naath, Narayanan Surendran, Chad L Stoner & Ayman El-Kattan

Pages: 591-608

Published online: 21 Jul 2006

AbstractforThe road map to oral bioavailability: an industrial perspective | Full Text | References | PDF (196.3 KB)

897 Views
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Drug Evaluation

Article

Tadalafil for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia

Ricardo R Gonzalez & Steven A Kaplan

Pages: 609-617

Published online: 21 Jul 2006

AbstractforTadalafil for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia | Full Text | References | PDF (99 KB)

236 Views
16 CrossRef citations
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Technology Evaluation

Article

Integrating invitro ADMET data through generic physiologically based pharmacokinetic models

David E Leahy

Pages: 619-628

Published online: 21 Jul 2006

AbstractforIntegrating invitro ADMET data through generic physiologically based pharmacokinetic models | Full Text | References | PDF (107.5 KB)

129 Views
32 CrossRef citations
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Article

Luminogenic cytochrome P450 assays

James J Cali, Dongping Ma, Mary Sobol, Daniel J Simpson, Susan Frackman, Troy D Good, William J Daily & David Liu

Pages: 629-645

Published online: 21 Jul 2006

AbstractforLuminogenic cytochrome P450 assays | Full Text | References | PDF (188.4 KB)

1335 Views
148 CrossRef citations
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Expert Opinion on Drug Metabolism & Toxicology (Vol.2, Iss.4, 2006)

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