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Volume 2, Issue 5

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 2, Issue 5 (2006)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 2, Issue 5 (2006)

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Review

Article

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy

Ichiro Ieiri, Hiroshi Takane, Takeshi Hirota, Kenji Otsubo & Shun Higuchi

Pages: 651-674

Published online: 03 Oct 2006

AbstractforGenetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy | Full Text | References | PDF (253.2 KB)

364 Views
48 CrossRef citations
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Article

Strategies to assess the drug interaction potential in translational medicine

Stefano Persiani & Patrice Larger

Pages: 675-686

Published online: 03 Oct 2006

AbstractforStrategies to assess the drug interaction potential in translational medicine | Full Text | References | PDF (133.8 KB)

65 Views
2 CrossRef citations
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Article

In vitro assays and biomarkers for drug-induced phospholipidosis

David K Monteith, Ryan E Morgan & Bartley Halstead

Pages: 687-696

Published online: 03 Oct 2006

AbstractforIn vitro assays and biomarkers for drug-induced phospholipidosis | Full Text | References | PDF (141.6 KB)

591 Views
38 CrossRef citations
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Article

Mechanistic biomarkers for cytotoxic acute kidney injury

Vishal S Vaidya & Joseph V Bonventre

Pages: 697-713

Published online: 03 Oct 2006

AbstractforMechanistic biomarkers for cytotoxic acute kidney injury | Full Text | References | PDF (193 KB)

271 Views
57 CrossRef citations
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Article

Preclinical formulations for discovery and toxicology: physicochemical challenges

Seshadri Neervannan

Pages: 715-731

Published online: 03 Oct 2006

AbstractforPreclinical formulations for discovery and toxicology: physicochemical challenges | Full Text | References | PDF (386.8 KB)

4080 Views
124 CrossRef citations
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Article

Enhancement of drug absorption by noncharged detergents through membrane and P-glycoprotein binding

Anna Seelig & Grégori Gerebtzoff

Pages: 733-752

Published online: 03 Oct 2006

AbstractforEnhancement of drug absorption by noncharged detergents through membrane and P-glycoprotein binding | Full Text | References | PDF (249.1 KB)

272 Views
61 CrossRef citations
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Article

Therapeutic resistance in lung cancer

Aalok Nadkar, Chirag Pungaliya, Kenneth Drake, Ewa Zajac, Sharad S Singhal & Sanjay Awasthi

Pages: 753-777

Published online: 03 Oct 2006

AbstractforTherapeutic resistance in lung cancer | Full Text | References | PDF (270 KB)

139 Views
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Drug Evaluation

Article

Inhaled human insulin ((insulin human [rDNA origin]) Inhalation Powder) in diabetes mellitus

Chantal Mathieu

Pages: 779-791

Published online: 03 Oct 2006

AbstractforInhaled human insulin ((insulin human [rDNA origin]) Inhalation Powder) in diabetes mellitus | Full Text | References | PDF (146.2 KB)

82 Views
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Article

Insulin aspart: a review

David Owens & Jiten Vora

Pages: 793-804

Published online: 03 Oct 2006

AbstractforInsulin aspart: a review | Full Text | References | PDF (146 KB)

347 Views
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Technology Evaluation

Article

A hierarchical screening methodology for physicochemical/ADME/Tox profiling

Robert S DeWitte & Russell H Robins

Pages: 805-817

Published online: 03 Oct 2006

AbstractforA hierarchical screening methodology for physicochemical/ADME/Tox profiling | Full Text | References | PDF (121.2 KB)

85 Views
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