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Expert Opinion on Drug Metabolism & Toxicology
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Volume 5, Issue 10

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 5, Issue 10 (2009)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 5, Issue 10 (2009)

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Reviews

Article

Liver tissue engineering in the evaluation of drug safety

Ajit Dash, Walker Inman, Keith Hoffmaster, Samantha Sevidal, Joan Kelly, R Scott Obach, Linda G Griffith & Steven R Tannenbaum PhD

Pages: 1159-1174

Published online: 29 Jul 2009

AbstractforLiver tissue engineering in the evaluation of drug safety | Full Text | References | PDF (1.3 MB)

844 Views
127 CrossRef citations
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Article

Identification of interspecies difference in hepatobiliary transporters to improve extrapolation of human biliary secretion

Yurong Lai PhD

Pages: 1175-1187

Published online: 17 Jul 2009

AbstractforIdentification of interspecies difference in hepatobiliary transporters to improve extrapolation of human biliary secretion | Full Text | References | PDF (408 KB)

670 Views
49 CrossRef citations
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Article

Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem

Maria A Croyle PhD

Pages: 1189-1211

Published online: 07 Sep 2009

AbstractforLong-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem | Full Text | References | PDF (909.5 KB)

118 Views
12 CrossRef citations
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Article

Phenylalanine 4-monooxygenase and the role of endobiotic metabolism enzymes in xenobiotic biotransformation

Glyn B Steventon & Stephen C Mitchell

Pages: 1213-1221

Published online: 04 Aug 2009

AbstractforPhenylalanine 4-monooxygenase and the role of endobiotic metabolism enzymes in xenobiotic biotransformation | Full Text | References | PDF (1.7 MB)

100 Views
7 CrossRef citations
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Article

Nrf2 and antioxidant defense against CYP2E1 toxicity

Arthur Cederbaum

Pages: 1223-1244

Published online: 11 Aug 2009

AbstractforNrf2 and antioxidant defense against CYP2E1 toxicity | Full Text | References | PDF (1.2 MB)

555 Views
46 CrossRef citations
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Article

QSAR of cytochrome inhibitors

Kunal Roy & Partha Pratim Roy

Pages: 1245-1266

Published online: 27 Aug 2009

AbstractforQSAR of cytochrome inhibitors | Full Text | References | PDF (476.6 KB)

193 Views
32 CrossRef citations
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Article

Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations

Ralph Clinckers PhD, Ilse Smolders PhD, Katia Vermoesen, Yvette Michotte PhD, Meindert Danhof PhD, Rob Voskuyl PhD & Oscar Della Pasqua PhD

Pages: 1267-1277

Published online: 17 Jul 2009

AbstractforPrediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations | Full Text | References | PDF (270.3 KB)

176 Views
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Drug Evaluations

Article

Balsalazide: a novel 5-aminosalicylate prodrug for the treatment of active ulcerative colitis

Jon Brendan Wiggins MD & Ramona Rajapakse MD

Pages: 1279-1284

Published online: 10 Sep 2009

AbstractforBalsalazide: a novel 5-aminosalicylate prodrug for the treatment of active ulcerative colitis | Full Text | References | PDF (204.5 KB)

306 Views
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Article

Clinical experience in treating hypertension with fixed-dose combination therapy: angiotensin II receptor blocker losartan plus hydrochlorothiazide

Masanori Abe MD, Kazuyoshi Okada & Koichi Matsumoto

Pages: 1285-1303

Published online: 17 Sep 2009

AbstractforClinical experience in treating hypertension with fixed-dose combination therapy: angiotensin II receptor blocker losartan plus hydrochlorothiazide | Full Text | References | PDF (504.3 KB)

304 Views
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Article

Neridronic acid for the treatment of bone metabolic diseases

Davide Gatti, Ombretta Viapiana, Luca Idolazzi, Elena Fracassi & Silvano Adami

Pages: 1305-1311

Published online: 17 Sep 2009

AbstractforNeridronic acid for the treatment of bone metabolic diseases | Full Text | References | PDF (256.2 KB)

305 Views
17 CrossRef citations
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Article

Saquinavir, the pioneer antiretroviral protease inhibitor

Charles JL la Porte PharmD PhD

Pages: 1313-1322

Published online: 08 Sep 2009

AbstractforSaquinavir, the pioneer antiretroviral protease inhibitor | Full Text | References | PDF (265.9 KB)

255 Views
27 CrossRef citations
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Article

GnRH antagonist, cetrorelix, for pituitary suppression in modern, patient-friendly assisted reproductive technology

Ilan Tur-Kaspa MD & Diego Ezcurra DVM MSc

Pages: 1323-1336

Published online: 17 Sep 2009

AbstractforGnRH antagonist, cetrorelix, for pituitary suppression in modern, patient-friendly assisted reproductive technology | Full Text | References | PDF (443.9 KB)

410 Views
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Article

Quinaprilat: a review of its pharmacokinetics, pharmacodynamics, toxicological data and clinical application

Arne Georg Kieback MD, Stephan B Felix MD & Thorsten Reffelmann MD

Pages: 1337-1347

Published online: 17 Sep 2009

AbstractforQuinaprilat: a review of its pharmacokinetics, pharmacodynamics, toxicological data and clinical application | Full Text | References | PDF (293.2 KB)

368 Views
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Expert Opinion on Drug Metabolism & Toxicology (Vol.5, Iss.10, 2009)

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