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Volume 6, Issue 7

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 6, Issue 7 (2010)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 6, Issue 7 (2010)

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Computational Sciences in Drug Metabolism and Toxicology: Editorial

Article

Computational science in drug metabolism and toxicology

Luis G Valerio Jr (Science and Research Staff) PhD

Pages: 781-784

Published online: 14 May 2010

AbstractforComputational science in drug metabolism and toxicology | Full Text | References | PDF (169.9 KB)

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Free Access

Computational Sciences in Drug Metabolism and Toxicology: Perspectives

Article

Computational toxicology at the European Commission's Joint Research Centre

Aleksandra Mostrag-Szlichtyng, José-Manuel Zaldívar Comenges & Andrew P Worth

Pages: 785-792

Published online: 06 May 2010

AbstractforComputational toxicology at the European Commission's Joint Research Centre | Full Text | References | PDF (244.9 KB)

168 Views
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Article

Regulatory use of computational toxicology tools and databases at the United States Food and Drug Administration's Office of Food Additive Safety

Kirk B Arvidson, Ronald Chanderbhan, Kristi Muldoon-Jacobs, Julie Mayer & Adejoke Ogungbesan

Pages: 793-796

Published online: 21 May 2010

AbstractforRegulatory use of computational toxicology tools and databases at the United States Food and Drug Administration's Office of Food Additive Safety | Full Text | References | PDF (167.8 KB)

318 Views
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Computational Sciences in Drug Metabolism and Toxicology: Reviews

Article

The computational prediction of genotoxicity

Russell T Naven (Principal Scientist) PhD, Shirley Louise-May (Principal Scientist) PhD & Nigel Greene (Associate Research Fellow) PhD

Pages: 797-807

Published online: 09 Jun 2010

AbstractforThe computational prediction of genotoxicity | Full Text | References | PDF (342.4 KB)

326 Views
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Article

Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays

Romualdo Benigni, Cecilia Bossa, Olga Tcheremenskaia & Alessandro Giuliani

Pages: 809-819

Published online: 03 May 2010

AbstractforAlternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays | Full Text | References | PDF (265 KB)

315 Views
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Article

Machine learning algorithms for the prediction of hERG and CYP450 binding in drug development

Anthony E Klon (Senior Scientist) PhD

Pages: 821-833

Published online: 14 May 2010

AbstractforMachine learning algorithms for the prediction of hERG and CYP450 binding in drug development | Full Text | References | PDF (282.6 KB)

249 Views
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Article

Structural ensemble in computational drug screening

Yoshifumi Fukunishi

Pages: 835-849

Published online: 14 May 2010

AbstractforStructural ensemble in computational drug screening | Full Text | References | PDF (420.4 KB)

160 Views
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Article

The challenges of in silico contributions to drug metabolism in lead optimization

Roy J Vaz, Ismael Zamora, Yi Li, Stephan Reiling, Jian Shen & Gabriele Cruciani

Pages: 851-861

Published online: 22 Jun 2010

AbstractforThe challenges of in silico contributions to drug metabolism in lead optimization | Full Text | References | PDF (473.3 KB)

342 Views
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Drug Evaluations

Article

Telmisartan: a review of its pharmacodynamic and pharmacokinetic properties

Sylvia Deppe, Rainer H Böger, Johanna Weiss & Ralf A Benndorf (Professor) MD

Pages: 863-871

Published online: 29 May 2010

AbstractforTelmisartan: a review of its pharmacodynamic and pharmacokinetic properties | Full Text | References | PDF (243.6 KB)

900 Views
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Article

Finasteride

Uzair B Chaudhary (Chief of Hematology/Oncology, Associate Professor of Clinical Medicine) MD & Jeffrey S Turner MD

Pages: 873-881

Published online: 11 Jun 2010

AbstractforFinasteride | Full Text | References | PDF (248.8 KB)

431 Views
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Foreword

Article

Foreword

Joris Roulleau (Senior Editor)

Page: i

Published online: 22 Jun 2010

CitationforForeword | Full Text | PDF (160.1 KB)

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Expert Opinion on Drug Metabolism & Toxicology (Vol.6, Iss.7, 2010)

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