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Volume 8, Issue 12

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 12 (2012)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 12 (2012)

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Research Article

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Page: 1

Published online: 16 Nov 2012

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Original Research

Article

Validated in vitro/in vivo correlation of prolonged-release oxycodone/naloxone with differing dissolution rates in relation to gastrointestinal transit times

Gill E Mundin, Kevin J Smith, Jana Mysicka, Gerhard Heun, Mathias Krämer, Udo Hahn & Christian Leuner

Pages: 1495-1503

Published online: 01 Oct 2012

AbstractforValidated in vitro/in vivo correlation of prolonged-release oxycodone/naloxone with differing dissolution rates in relation to gastrointestinal transit times | Full Text | References | PDF (430.2 KB)

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Reviews

Review Article

The effects of gastric bypass surgery on drug absorption and pharmacokinetics

Dion R Brocks (Professor and Associate Dean) , Mohamed Ben-Eltriki, Raniah Q Gabr & Raj S Padwal

Pages: 1505-1519

Published online: 24 Sep 2012

AbstractforThe effects of gastric bypass surgery on drug absorption and pharmacokinetics | Full Text | References | PDF (492.3 KB)

3371 Views
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Review Article

Latest advances in predicting DILI in human subjects: focus on biomarkers

Maiyen Tran Hawkins & James H Lewis

Pages: 1521-1530

Published online: 24 Sep 2012

AbstractforLatest advances in predicting DILI in human subjects: focus on biomarkers | Full Text | References | PDF (233.2 KB)

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Review Article

The metabolic and toxicological considerations for immunosuppressive drugs used during pancreas transplantation

Erika B Rangel

Pages: 1531-1548

Published online: 17 Sep 2012

AbstractforThe metabolic and toxicological considerations for immunosuppressive drugs used during pancreas transplantation | Full Text | References | PDF (311.5 KB)

281 Views
15 CrossRef citations
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Review Article

CYP2C metabolism of oral antidiabetic drugs - impact on pharmacokinetics, drug interactions and pharmacogenetic aspects

Andreas Holstein, Winfried Beil & Peter Kovacs

Pages: 1549-1563

Published online: 16 Nov 2012

AbstractforCYP2C metabolism of oral antidiabetic drugs - impact on pharmacokinetics, drug interactions and pharmacogenetic aspects | Full Text | References | PDF (258.6 KB)

788 Views
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Review Article

Multidrug and toxin extrusion proteins as transporters of antimicrobial drugs

Anne T Nies, Katja Damme, Elke Schaeffeler & Matthias Schwab

Pages: 1565-1577

Published online: 13 Sep 2012

AbstractforMultidrug and toxin extrusion proteins as transporters of antimicrobial drugs | Full Text | References | PDF (412.4 KB)

739 Views
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Review Article

Latest advances in computational genotoxicity prediction

Russell T Naven, Nigel Greene & Richard V Williams

Pages: 1579-1587

Published online: 24 Sep 2012

AbstractforLatest advances in computational genotoxicity prediction | Full Text | References | PDF (411.8 KB)

395 Views
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Drug Evaluations

Article

Is there a role for tirapazamine in the treatment of cervical cancer?

Prafull Ghatage & Hassan Sabagh

Pages: 1589-1597

Published online: 04 Oct 2012

AbstractforIs there a role for tirapazamine in the treatment of cervical cancer? | Full Text | References | PDF (314.8 KB)

204 Views
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Article

Etoricoxib and the treatment of ankylosing spondylitis

Rik J Lories (KU Leuven Research Professor) MD PhD

Pages: 1599-1608

Published online: 06 Nov 2012

Abstractfor Etoricoxib and the treatment of ankylosing spondylitis | Full Text | References | PDF (408.2 KB)

457 Views
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Article

Pharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications

David J Greenblatt & Gary K Zammit

Pages: 1609-1618

Published online: 06 Nov 2012

AbstractforPharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications | Full Text | References | PDF (551.3 KB)

559 Views
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Expert Opinion on Drug Metabolism & Toxicology (Vol.8, Iss.12, 2012)

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