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Expert Opinion on Therapeutic Targets
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Volume 12, Issue 12

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 12, Issue 12 (2008)

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Expert Opinion on Therapeutic Targets, Volume 12, Issue 12 (2008)

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Original Research

Article

A novel IKK inhibitor suppresses heart failure and chronic remodeling after myocardial ischemia via MMP alteration

Shin Wakatsuki, Jun-ichi Suzuki, Masahito Ogawa, Mayumi Masumura, Susumu Muto, Tomoko Shimizu, Kiyoshi Takayama, Akiko Itai & Mitsuaki Isobe

Pages: 1469-1476

Published online: 13 Nov 2008

AbstractforA novel IKK inhibitor suppresses heart failure and chronic remodeling after myocardial ischemia via MMP alteration | Full Text | References | PDF (3.1 MB)

155 Views
15 CrossRef citations
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Original research

Article

Plasma levels of osteopontin before and 24 h after percutaneous coronary intervention

P Georgiadou, EK Iliodromitis, F Kolokathis, M Mavroidis, I Andreadou, M Demopoulou, Ch Varounis, Y Capetanaki, H Boudoulas & D Th Kremastinos

Pages: 1477-1480

Published online: 13 Nov 2008

AbstractforPlasma levels of osteopontin before and 24 h after percutaneous coronary intervention | Full Text | References | PDF (235.7 KB)

51 Views
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Reviews

Article

Toll-like receptors as therapeutic targets in cystic fibrosis

Catherine M Greene BA PhD, Peter Branagan MB BCh BAO & Noel G McElvaney MB BCh BAO FRCPI, FRCPC

Pages: 1481-1495

Published online: 13 Nov 2008

AbstractforToll-like receptors as therapeutic targets in cystic fibrosis | Full Text | References | PDF (339.1 KB)

179 Views
25 CrossRef citations
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Review

Article

Inflammation and the glutamate system in schizophrenia: implications for therapeutic targets and drug development

Norbert Müller

Pages: 1497-1507

Published online: 13 Nov 2008

AbstractforInflammation and the glutamate system in schizophrenia: implications for therapeutic targets and drug development | Full Text | References | PDF (1 MB)

346 Views
29 CrossRef citations
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Article

Autophagy: a target for therapeutic interventions in myocardial pathophysiology

Antonis Halapas, Athanasios Armakolas & Michael Koutsilieris

Pages: 1509-1522

Published online: 13 Nov 2008

AbstractforAutophagy: a target for therapeutic interventions in myocardial pathophysiology | Full Text | References | PDF (352.8 KB)

135 Views
8 CrossRef citations
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Article

Current and emerging paradigms in the therapeutic management of atherosclerosis

Atul Tiwari PhD

Pages: 1523-1546

Published online: 13 Nov 2008

AbstractforCurrent and emerging paradigms in the therapeutic management of atherosclerosis | Full Text | References | PDF (474.4 KB)

83 Views
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Article

Targeting cerebrovascular Rho-kinase in stroke

Hwa Kyoung Shin PhD, Salvatore Salomone MD PhD & Cenk Ayata MD

Pages: 1547-1564

Published online: 13 Nov 2008

AbstractforTargeting cerebrovascular Rho-kinase in stroke | Full Text | References | PDF (1.2 MB)

244 Views
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Article

Targeting PPAR as a therapy to treat multiple sclerosis

John J Bright, Crystal C Walline, Sarvanan Kanakasabai & Sharmistha Chakraborty

Pages: 1565-1575

Published online: 13 Nov 2008

AbstractforTargeting PPAR as a therapy to treat multiple sclerosis | Full Text | References | PDF (313.3 KB)

146 Views
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Article

The role of matrix metalloproteinases in the pathophysiology and progression of human nervous system malignancies: a chance for the development of targeted therapeutic approaches?

Ioannis Koutroulis, Apostolos Zarros & Stamatios Theocharis

Pages: 1577-1586

Published online: 13 Nov 2008

AbstractforThe role of matrix metalloproteinases in the pathophysiology and progression of human nervous system malignancies: a chance for the development of targeted therapeutic approaches? | Full Text | References | PDF (248.6 KB)

99 Views
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Key Paper Evaluation

Article

Targeting the angiotensin pathway in idiopathic pulmonary fibrosis

Evaluation of: Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice. Respir Res 2008;9:43

Sabina A Antoniu MD PhD

Pages: 1587-1590

Published online: 13 Nov 2008

AbstractforTargeting the angiotensin pathway in idiopathic pulmonary fibrosis | Full Text | References | PDF (209.5 KB)

85 Views
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Meeting Highlights

Article

Mast cells in health and disease: from basic science to clinical application

4 – 5 July 2008, Stuttgart, Germany

Dennis Kirchhoff, Stephan C Bischoff, Marcus Maurer & Thomas M Zollner

Pages: 1591-1594

Published online: 13 Nov 2008

AbstractforMast cells in health and disease: from basic science to clinical application | Full Text | References | PDF (200.4 KB)

54 Views
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