Expert Opinion on Therapeutic Targets, Volume 13, Issue 3 (2009)

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Expert Opinion on Therapeutic Targets, Volume 13, Issue 3 (2009)

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Original Research

Article
Aortic stiffness in diabetes mellitus – association with glutamine and heat shock protein 70 expression: a pilot study based on an experimental rodent model
Murat Ugurlucan, Dilek Erer, Yusuf Kalko, Funda Gungor, Aptullah Haholu, Murat Basaran, Maciej Banach, Jacek Rysz, Dimitri P Mikhailidis, Emin Tireli, Enver Dayioglu & Ufuk Alpagut
Pages: 267-274
Published online: 08 May 2009
AbstractforAortic stiffness in diabetes mellitus – association with glutamine and heat shock protein 70 expression: a pilot study based on an experimental rodent model | Full Text | References | PDF (2 MB)
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  • 8 CrossRef citations
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Article
Chronic β-AR activation-induced calpain activation and impaired eNOS–Akt signaling mediates cardiac injury in ovariectomized female rats
Md. Shenuarin Bhuiyan, Norifumi Shioda & Kohji Fukunaga
Pages: 275-286
Published online: 08 May 2009
AbstractforChronic β-AR activation-induced calpain activation and impaired eNOS–Akt signaling mediates cardiac injury in ovariectomized female rats | Full Text | References | PDF (1.1 MB)
  • 103 Views
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Reviews

Article
Macrophage metalloelastase (MMP-12) as a target for inflammatory respiratory diseases
Vincent Lagente, Catherine Le Quement & Elisabeth Boichot
Pages: 287-295
Published online: 08 May 2009
AbstractforMacrophage metalloelastase (MMP-12) as a target for inflammatory respiratory diseases | Full Text | References | PDF (286.8 KB)
  • 889 Views
  • 90 CrossRef citations
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Article
CCR9 and inflammatory bowel disease
Christian Koenecke MD & Reinhold Förster PhD
Pages: 297-306
Published online: 08 May 2009
AbstractforCCR9 and inflammatory bowel disease | Full Text | References | PDF (343.2 KB)
  • 744 Views
  • 33 CrossRef citations
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Article
HSP 70 and atherosclerosis – protector or activator?
Agata Bielecka-Dabrowa, Marcin Barylski, Dimitri P Mikhailidis, Jacek Rysz & Maciej Banach MD PhD FESC FASA FSGC
Pages: 307-317
Published online: 08 May 2009
AbstractforHSP 70 and atherosclerosis – protector or activator? | Full Text | References | PDF (364 KB)
  • 258 Views
  • 38 CrossRef citations
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Article
The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease
Antonio Cuadrado, Paz Moreno-Murciano & José Pedraza-Chaverri
Pages: 319-329
Published online: 08 May 2009
AbstractforThe transcription factor Nrf2 as a new therapeutic target in Parkinson's disease | Full Text | References | PDF (343.2 KB)
  • 596 Views
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Article
Lipid metabolism and Alzheimer's disease: pathways and possibilities
Uday Saxena PhD
Pages: 331-338
Published online: 08 May 2009
AbstractforLipid metabolism and Alzheimer's disease: pathways and possibilities | Full Text | References | PDF (331.2 KB)
  • 188 Views
  • 7 CrossRef citations
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Article
Mechanisms of tumor resistance to EGFR-targeted therapies
Elizabeth A Hopper-Borge, Rochelle E Nasto, Vladimir Ratushny, Louis M Weiner, Erica A Golemis & Igor Astsaturov
Pages: 339-362
Published online: 08 May 2009
AbstractforMechanisms of tumor resistance to EGFR-targeted therapies | Full Text | References | PDF (1.3 MB)
  • 276 Views
  • 67 CrossRef citations
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Article
Targeting the extracellular signature of metastatic colorectal cancers
Serena Marchiò, Wadih Arap & Renata Pasqualini
Pages: 363-379
Published online: 08 May 2009
AbstractforTargeting the extracellular signature of metastatic colorectal cancers | Full Text | References | PDF (656.5 KB)
  • 145 Views
  • 6 CrossRef citations
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Key Paper Evaluation

Article
Targeting platelet-derived growth factor with imatinib in idiopathic pulmonary arterial hypertension
Evaluation of: Perros F, Montani D, Dorfmuller P, et al. Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med 2008;178(1):81-8
Sabina A Antoniu
Pages: 381-383
Published online: 08 May 2009
AbstractforTargeting platelet-derived growth factor with imatinib in idiopathic pulmonary arterial hypertension | Full Text | References | PDF (218.3 KB)
  • 62 Views
  • 2 CrossRef citations
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