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Expert Opinion on Therapeutic Targets
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Volume 18, Issue 12

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 18, Issue 12 (2014)

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Expert Opinion on Therapeutic Targets, Volume 18, Issue 12 (2014)

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Original Research

Article

MicroRNA-34a regulates cardiac fibrosis after myocardial infarction by targeting Smad4

Ying Huang, Yuan Qi, Jian-Qing Du & Dai-fu Zhang

Pages: 1355-1365

Published online: 17 Oct 2014

AbstractforMicroRNA-34a regulates cardiac fibrosis after myocardial infarction by targeting Smad4 | Full Text | References | PDF (730.9 KB) | Supplemental

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Article

Hepatotoxicity induced by neonatal exposure to diethylstilbestrol is maintained throughout adulthood via the nuclear receptor SHP

Aurélie Vega, Marine Baptissart, Emmanuelle Martinot, Jean-Paul Saru, Silvère Baron, Kristina Schoonjans & David H Volle

Pages: 1367-1376

Published online: 29 Sep 2014

AbstractforHepatotoxicity induced by neonatal exposure to diethylstilbestrol is maintained throughout adulthood via the nuclear receptor SHP | Full Text | References | PDF (752.7 KB) | Supplemental

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Reviews

Review Article

Aurora kinase A inhibitors: promising agents in antitumoral therapy

Marcos Malumbres PhD & Ignacio Pérez de Castro PhD

Pages: 1377-1393

Published online: 09 Sep 2014

AbstractforAurora kinase A inhibitors: promising agents in antitumoral therapy | Full Text | References | PDF (572.6 KB) | Supplemental

817 Views
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Review Article

Multi-targeted molecular therapeutic approach in aggressive neuroblastoma: the effect of Focal Adhesion Kinase–Src–Paxillin system

Panagiotis Kratimenos MD, Ioannis Koutroulis, Dante Marconi, Vasiliki Syriopoulou, Maria Delivoria-Papadopoulos, George P Chrousos & Stamatios Theocharis

Pages: 1395-1406

Published online: 05 Sep 2014

AbstractforMulti-targeted molecular therapeutic approach in aggressive neuroblastoma: the effect of Focal Adhesion Kinase–Src–Paxillin system | Full Text | References | PDF (346.4 KB)

392 Views
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Review Article

The PD-1 pathway as a therapeutic target to overcome immune escape mechanisms in cancer

Brian S Henick MD, Roy S Herbst MD PhD & Sarah B Goldberg MD MPH

Pages: 1407-1420

Published online: 21 Oct 2014

AbstractforThe PD-1 pathway as a therapeutic target to overcome immune escape mechanisms in cancer | Full Text | References | PDF (401.5 KB)

949 Views
17 CrossRef citations
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Review Article

The potential for targeting HER2 therapeutically in esophageal cancer – a grasp at straws?

Faik G Uzunoglu MD, Alexandra M Koenig MD & Jakob R Izbicki MD

Pages: 1421-1426

Published online: 26 Sep 2014

AbstractforThe potential for targeting HER2 therapeutically in esophageal cancer – a grasp at straws? | Full Text | References | PDF (185.9 KB)

181 Views
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Review Article

Antithrombotic therapy: new areas to understand efficacy and bleeding

James W Wisler MD & Richard C Becker MD

Pages: 1427-1434

Published online: 27 Oct 2014

AbstractforAntithrombotic therapy: new areas to understand efficacy and bleeding | Full Text | References | PDF (195.1 KB)

243 Views
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Review Article

Filamin A interacting protein 1-like as a therapeutic target in cancer

Mijung Kwon PhD & Steven K Libutti MD

Pages: 1435-1447

Published online: 09 Sep 2014

AbstractforFilamin A interacting protein 1-like as a therapeutic target in cancer | Full Text | References | PDF (674.6 KB)

303 Views
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Review Article

Targeting FXR in cholestasis: hype or hope

Stefano Fiorucci, Eleonora Distrutti, Patrizia Ricci, Vittorio Giuliano, Annibale Donini & Franco Baldelli

Pages: 1449-1459

Published online: 09 Sep 2014

AbstractforTargeting FXR in cholestasis: hype or hope | Full Text | References | PDF (394.2 KB)

801 Views
3 CrossRef citations
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Review Article

Sigma-1 receptor chaperones in neurodegenerative and psychiatric disorders

Shang-Yi A Tsai, Michael J Pokrass, Neal R Klauer, Nicole E De Credico & Tsung-Ping Su

Pages: 1461-1476

Published online: 21 Oct 2014

AbstractforSigma-1 receptor chaperones in neurodegenerative and psychiatric disorders | Full Text | References | PDF (462 KB)

612 Views
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Research Article

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