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Volume 19, Issue 12

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 12 (2015)

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 12 (2015)

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Editorial

CD44 as a drug delivery target in human cancers: where are we now?

Ibrahim H Sahin & Jim Klostergaard

Pages: 1587-1591

Published online: 16 Sep 2015

AbstractforCD44 as a drug delivery target in human cancers: where are we now? | Full Text | References | PDF (218.7 KB)

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Free Access

Original Research

Article

Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment

Francesca Perut PhD, Fabrizio Carta, Gloria Bonuccelli, Giulia Grisendi, Gemma Di Pompo, Sofia Avnet, Francesca Vittoria Sbrana, Shigekuni Hosogi, Massimo Dominici, Katsuyuki Kusuzaki, Claudiu T Supuran & Nicola Baldini

Pages: 1593-1605

Published online: 10 Sep 2015

AbstractforCarbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment | Full Text | References | PDF (893.4 KB)

277 Views
24 CrossRef citations
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Article

Potential effects of vildagliptin on biomarkers associated with prothrombosis in diabetes mellitus

Sana Khan B. Pharm, Saba Khan, Bibhu Prasad Panda (Assistant Professor) , Mohd Akhtar & Abul Kalam Najmi (Assistant Professor)

Pages: 1607-1616

Published online: 11 Sep 2015

AbstractforPotential effects of vildagliptin on biomarkers associated with prothrombosis in diabetes mellitus | Full Text | References | PDF (406.2 KB)

272 Views
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Article

Endothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes

Elisabetta Mandosi, Elisa Giannetta, Tiziana Filardi, Manuela Lococo, Camilla Bertolini, Mara Fallarino, Daniele Gianfrilli, Mary Anna Venneri, Luisa Lenti, Andrea Lenzi & Susanna Morano

Pages: 1617-1622

Published online: 15 Jul 2015

AbstractforEndothelial dysfunction markers as a therapeutic target for Sildenafil treatment and effects on metabolic control in type 2 diabetes | Full Text | References | PDF (256.7 KB)

325 Views
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Reviews

Hepatocellular carcinoma treatment over sorafenib: epigenetics, microRNAs and microenvironment. Is there a light at the end of the tunnel?

Antonio Gnoni, Daniele Santini, Mario Scartozzi, Antonio Russo, Antonella Licchetta, Vincenzo Palmieri, Luigi Lupo, Luca Faloppi, Giuseppe Palasciano, Vincenzo Memeo, Gioacchino Angarano, Oronzo Brunetti, Attilio Guarini, Salvatore Pisconti, Vito Lorusso & Nicola Silvestris MD

Pages: 1623-1635

Published online: 27 Jul 2015

AbstractforHepatocellular carcinoma treatment over sorafenib: epigenetics, microRNAs and microenvironment. Is there a light at the end of the tunnel? | Full Text | References | PDF (409 KB)

716 Views
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Effect of bacterial and host factors on Helicobacter pylori eradication therapy

Takahiro Uotani, Muhammad Miftahussurur & Yoshio Yamaoka

Pages: 1637-1650

Published online: 06 Aug 2015

AbstractforEffect of bacterial and host factors on Helicobacter pylori eradication therapy | Full Text | References | PDF (423.4 KB)

155 Views
22 CrossRef citations
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Therapeutic targeting of Toll-like receptors in cutaneous disorders

Nassim Matin MD-MPH, Omidreza Tabatabaie MD-MPH, Payam Mohammadinejad MD & Nima Rezaei MD PhD

Pages: 1651-1663

Published online: 18 Jul 2015

AbstractforTherapeutic targeting of Toll-like receptors in cutaneous disorders | Full Text | References | PDF (459.6 KB)

190 Views
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Galanin receptors as a potential target for neurological disease

Krista Freimann (PhD student) , Kaido Kurrikoff (Senior Researcher) & Ülo Langel (Professor) (Professor)

Pages: 1665-1676

Published online: 28 Jul 2015

AbstractforGalanin receptors as a potential target for neurological disease | Full Text | References | PDF (371.9 KB)

652 Views
19 CrossRef citations
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Dupuytren’s disease therapy: targeting the vicious cycle of myofibroblasts?

Maria Musumeci PhD, Gianluca Vadalà MD PhD, Fabrizio Russo MD, Federica Pelacchi PhD, Angela Lanotte MD & Vincenzo Denaro MD

Pages: 1677-1687

Published online: 26 Aug 2015

AbstractforDupuytren’s disease therapy: targeting the vicious cycle of myofibroblasts? | Full Text | References | PDF (490.5 KB)

267 Views
6 CrossRef citations
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Bacterial, fungal and protozoan carbonic anhydrases as drug targets

Clemente Capasso & Claudiu T Supuran

Pages: 1689-1704

Published online: 01 Aug 2015

AbstractforBacterial, fungal and protozoan carbonic anhydrases as drug targets | Full Text | References | PDF (740.7 KB)

370 Views
165 CrossRef citations
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MicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer

Mohammad Alam Jafri, Syed Kashif Zaidi, Shakeel Ahmed Ansari, Mohammed Hussein Al-Qahtani & Jerry W Shay

Pages: 1705-1723

Published online: 18 Jul 2015

AbstractforMicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer | Full Text | References | PDF (769 KB)

385 Views
11 CrossRef citations
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Role of sphingomyelinases in neurological disorders

Wei-Yi Ong, Deron R Herr, Tahira Farooqui, Eng-Ang Ling & Akhlaq A Farooqui

Pages: 1725-1742

Published online: 04 Aug 2015

AbstractforRole of sphingomyelinases in neurological disorders | Full Text | References | PDF (543.8 KB)

971 Views
30 CrossRef citations
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