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Expert Opinion on Therapeutic Targets
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Volume 19, Issue 8

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 8 (2015)

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 8 (2015)

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Vol 28, 2024 Vol 27, 2023 Vol 26, 2022 Vol 25, 2021 Vol 24, 2020 Vol 23, 2019 Vol 22, 2018 Vol 21, 2017 Vol 20, 2016 Volume 19, 2015 Vol 18, 2014 Vol 17, 2013 Vol 16, 2012 Vol 15, 2011 Vol 14, 2010 Vol 13, 2009 Vol 12, 2008 Vol 11, 2007 Vol 10, 2006 Vol 9, 2005 Vol 8, 2004 Vol 7, 2003 Vol 6, 2002 Vol 5, 2001 Vol 5, 2001 Vol 4, 2000 Vol 3, 1999 Vol 2, 1998 Vol 1, 1997

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Editorial

The potential of sestrins as therapeutic targets for diabetes

Xiaocheng Charlie Dong PhD

Pages: 1011-1015

Published online: 05 May 2015

AbstractforThe potential of sestrins as therapeutic targets for diabetes | Full Text | References | PDF (573.4 KB)

2106 Views
17 CrossRef citations
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Free Access

Original Research

Article

MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1

Paula Mussnich, Roberta Rosa, Roberto Bianco, Alfredo Fusco & Daniela D’Angelo

Pages: 1017-1026

Published online: 24 Jun 2015

AbstractforMiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1 | Full Text | References | PDF (690.7 KB)

340 Views
58 CrossRef citations
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Article

MicroRNA expression in BRAF-mutated and wild-type metastatic melanoma and its correlation with response duration to BRAF inhibitors

Rosamaria Pinto, Sabino Strippoli, Simona De Summa, Anna Albano, Amalia Azzariti, Gabriella Guida, Ondina Popescu, Vito Lorusso, Michele Guida & Stefania Tommasi

Pages: 1027-1035

Published online: 09 Jul 2015

AbstractforMicroRNA expression in BRAF-mutated and wild-type metastatic melanoma and its correlation with response duration to BRAF inhibitors | Full Text | References | PDF (482.3 KB)

314 Views
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Review

Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes

Lara Bellini, Mélanie Campana, Rana Mahfouz, Aurélie Carlier, Julien Véret, Christophe Magnan, Eric Hajduch & Hervé Le Stunff

Pages: 1037-1050

Published online: 26 Mar 2015

AbstractforTargeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes | Full Text | References | PDF (601.3 KB)

851 Views
40 CrossRef citations
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Regulation of extracellular Zn²⁺ homeostasis in the hippocampus as a therapeutic target for Alzheimer’s disease

Atsushi Takeda & Haruna Tamano

Pages: 1051-1058

Published online: 27 Mar 2015

AbstractforRegulation of extracellular Zn²⁺ homeostasis in the hippocampus as a therapeutic target for Alzheimer’s disease | Full Text | References | PDF (365.2 KB)

162 Views
9 CrossRef citations
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Blood–brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery

William M Pardridge

Pages: 1059-1072

Published online: 02 May 2015

AbstractforBlood–brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery | Full Text | References | PDF (628 KB)

1671 Views
98 CrossRef citations
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Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight

Ying Gao, Dolores D Mruk & C Yan Cheng

Pages: 1073-1090

Published online: 26 Apr 2015

AbstractforSertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight | Full Text | References | PDF (693 KB)

292 Views
76 CrossRef citations
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The therapeutic potential of regulatory T cells for the treatment of autoimmune disease

Jeffrey A Bluestone (A.W. and Mary Margaret Clausen Distinguished Professor) PhD, Eleonora Trotta PhD & Daqi Xu PhD

Pages: 1091-1103

Published online: 16 Apr 2015

AbstractforThe therapeutic potential of regulatory T cells for the treatment of autoimmune disease | Full Text | References | PDF (627.7 KB)

1178 Views
67 CrossRef citations
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Adiponectin and its receptor signaling: an anti-cancer therapeutic target and its implications for anti-tumor immunity

Arnav Katira & Peng H Tan

Pages: 1105-1125

Published online: 07 May 2015

AbstractforAdiponectin and its receptor signaling: an anti-cancer therapeutic target and its implications for anti-tumor immunity | Full Text | References | PDF (827.3 KB)

427 Views
10 CrossRef citations
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The role of probiotics on each component of the metabolic syndrome and other cardiovascular risks

Bruna Miglioranza Scavuzzi MSc, Lucia Helena da Silva Miglioranza PhD, Fernanda Carla Henrique MSc, Thanise Pitelli Paroschi MSc, Marcell Alysson Batisti Lozovoy PhD, Andréa Name Colado Simão PhD & Isaias Dichi MD PhD

Pages: 1127-1138

Published online: 15 Apr 2015

AbstractforThe role of probiotics on each component of the metabolic syndrome and other cardiovascular risks | Full Text | References | PDF (398.1 KB)

473 Views
33 CrossRef citations
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The potential of LINGO-1 as a therapeutic target for essential tremor

José AG Agúndez MD PhD, Félix Javier Jiménez-Jimenez MD PhD, Hortensia Alonso-Navarro MD PhD & Elena García-Martín MD PhD

Pages: 1139-1148

Published online: 10 Apr 2015

AbstractforThe potential of LINGO-1 as a therapeutic target for essential tremor | Full Text | References | PDF (322.9 KB)

329 Views
9 CrossRef citations
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