Expert Opinion on Therapeutic Targets, Volume 21, Issue 4 (2017)

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Expert Opinion on Therapeutic Targets, Volume 21, Issue 4 (2017)

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Editorial

Editorial
The identification of TNFR5 as a therapeutic target in diabetes
Mark D. Turner
Pages: 349-351
Published online: 02 Mar 2017
First Page PreviewforThe identification of TNFR5 as a therapeutic target in diabetes | Full Text | References | PDF (405.9 KB)
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Editorial
The emergence of TNIK as a therapeutic target for colorectal cancer
Mari Masuda & Tesshi Yamada
Pages: 353-355
Published online: 28 Feb 2017
First Page PreviewforThe emergence of TNIK as a therapeutic target for colorectal cancer | Full Text | References | PDF (588.2 KB)
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Original Research

Article
Patients with acute myeloid leukemia can be subclassified based on the constitutive cytokine release of the leukemic cells; the possible clinical relevance and the importance of cellular iron metabolism
Annette K. Brenner, Tor Henrik Anderson Tvedt, Ina Nepstad, Kristin P. Rye, Karen M. Hagen, Håkon Reikvam & Øystein Bruserud
Pages: 357-369
Published online: 03 Mar 2017
AbstractforPatients with acute myeloid leukemia can be subclassified based on the constitutive cytokine release of the leukemic cells; the possible clinical relevance and the importance of cellular iron metabolism | Full Text | References | PDF (1.6 MB) | Supplemental
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Review

Review
Nutrient sensing pathways as therapeutic targets for healthy ageing
Anna Aiello, Giulia Accardi, Giuseppina Candore, Caterina Maria Gambino, Mario Mirisola, Giusi Taormina, Claudia Virruso & Calogero Caruso
Pages: 371-380
Published online: 17 Feb 2017
AbstractforNutrient sensing pathways as therapeutic targets for healthy ageing | Full Text | References | PDF (853 KB)
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Review
Genetic risk variants as therapeutic targets for Crohn’s disease
Tommaso Gabbani, Simona Deiana, Margherita Marocchi & Vito Annese
Pages: 381-390
Published online: 01 Mar 2017
AbstractforGenetic risk variants as therapeutic targets for Crohn’s disease | Full Text | References | PDF (717.9 KB)
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Review
Targeting CPS1 in the treatment of Carbamoyl phosphate synthetase 1 (CPS1) deficiency, a urea cycle disorder
Carmen Diez-Fernandez & Johannes Häberle
Pages: 391-399
Published online: 20 Feb 2017
AbstractforTargeting CPS1 in the treatment of Carbamoyl phosphate synthetase 1 (CPS1) deficiency, a urea cycle disorder | Full Text | References | PDF (996 KB)
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Review
Tp53 and its potential therapeutic role as a target in bladder cancer
Chiara Ciccarese, Francesco Massari, Ana Blanca, Giampaolo Tortora, Rodolfo Montironi, Liang Cheng, Marina Scarpelli, Maria R Raspollini, Nuno Vau, Jorge Fonseca & Antonio Lopez-Beltran
Pages: 401-414
Published online: 01 Mar 2017
AbstractforTp53 and its potential therapeutic role as a target in bladder cancer | Full Text | References | PDF (1.3 MB)
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Review
Implications of Toll-like receptors in Ebola infection
Amene Saghazadeh & Nima Rezaei
Pages: 415-425
Published online: 01 Mar 2017
AbstractforImplications of Toll-like receptors in Ebola infection | Full Text | References | PDF (1.5 MB)
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Review
TSHR as a therapeutic target in Graves’ disease
Terry J. Smith
Pages: 427-432
Published online: 06 Feb 2017
AbstractforTSHR as a therapeutic target in Graves’ disease | Full Text | References | PDF (456.5 KB)
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Review
PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis
Sindhu Koushik, Nivedita Joshi, Shruthi Nagaraju, Sameer Mahmood, Krishna Mudeenahally, Ramya Padmavathy, Sooriya Kumar Jegatheesan, Ramesh Mullangi & Sriram Rajagopal
Pages: 433-447
Published online: 22 Feb 2017
AbstractforPAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis | Full Text | References | PDF (1.7 MB)
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Letter to the Editor

Letter
Utilities of AAV vectors in in vivo phenotypic screening and functional studies
Ki Jeong Lee & Yang Li
Pages: 449-450
Published online: 28 Feb 2017
CitationforUtilities of AAV vectors in in vivo phenotypic screening and functional studies | Full Text | References | PDF (232.5 KB)
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