Expert Opinion on Therapeutic Targets, Volume 22, Issue 7 (2018)

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Expert Opinion on Therapeutic Targets, Volume 22, Issue 7 (2018)

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Editorial

Editorial
Targeted therapy to annihilate the immune-evading phenotype in cancer evolution
Ariel Fernández
Pages: 559-562
Published online: 13 Mar 2018
First Page PreviewforTargeted therapy to annihilate the immune-evading phenotype in cancer evolution | Full Text | References | PDF (560.7 KB)
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Editorial
How to say NO to vascular disruption and stem cell mobilization
Diana Passaro & Dominique Bonnet
Pages: 563-565
Published online: 17 Jun 2018
First Page PreviewforHow to say NO to vascular disruption and stem cell mobilization | Full Text | References | PDF (436.5 KB)
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Review

Review
Roles of macrophage migration inhibitory factor in Guillain-Barré syndrome and experimental autoimmune neuritis: beneficial or harmful?
Donghui Shen, Yue Lang, Fengna Chu, Xiujuan Wu, Ying Wang, Xiangyu Zheng, Hong-Liang Zhang, Jie Zhu & Kangding Liu
Pages: 567-577
Published online: 11 Jun 2018
AbstractforRoles of macrophage migration inhibitory factor in Guillain-Barré syndrome and experimental autoimmune neuritis: beneficial or harmful? | Full Text | References | PDF (1.2 MB)
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Review
Progranulin as a therapeutic target for dementia
Daniela Galimberti, Chiara Fenoglio & Elio Scarpini
Pages: 579-585
Published online: 22 Jun 2018
AbstractforProgranulin as a therapeutic target for dementia | Full Text | References | PDF (891.4 KB)
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Review
Triggering receptor expressed on myeloid cells 2 (TREM2): a potential therapeutic target for Alzheimer disease?
Yuetiva Deming, Zeran Li, Bruno A. Benitez & Carlos Cruchaga
Pages: 587-598
Published online: 20 Jun 2018
AbstractforTriggering receptor expressed on myeloid cells 2 (TREM2): a potential therapeutic target for Alzheimer disease? | Full Text | References | PDF (1.7 MB)
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Review
Mutant ATRX: uncovering a new therapeutic target for glioma
Santiago Haase, María Belén Garcia-Fabiani, Stephen Carney, David Altshuler, Felipe J. Núñez, Flor M. Méndez, Fernando Núñez, Pedro R. Lowenstein & Maria G. Castro
Pages: 599-613
Published online: 20 Jun 2018
AbstractforMutant ATRX: uncovering a new therapeutic target for glioma | Full Text | References | PDF (1.8 MB)
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Review
Targeting glucose-dependent insulinotropic polypeptide receptor for neurodegenerative disorders
Mahip K. Verma, Rajan Goel, Nandakumar Krishnadas & Kumar V. S. Nemmani
Pages: 615-628
Published online: 22 Jun 2018
AbstractforTargeting glucose-dependent insulinotropic polypeptide receptor for neurodegenerative disorders | Full Text | References | PDF (1.4 MB)
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Review
Trabecular meshwork ECM remodeling in glaucoma: could RAS be a target?
Puneet Agarwal & Renu Agarwal
Pages: 629-638
Published online: 14 Jun 2018
AbstractforTrabecular meshwork ECM remodeling in glaucoma: could RAS be a target? | Full Text | References | PDF (976.2 KB)
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Original Research

Article
Two acute myeloid leukemia patient subsets are identified based on the constitutive PI3K-Akt-mTOR signaling of their leukemic cells; a functional, proteomic, and transcriptomic comparison
Ina Nepstad, Kimberley J. Hatfield, Elise Aasebø, Maria Hernandez-Valladares, Annette K. Brenner, Sushma Bartaula-Brevik, Frode Berven, Frode Selheim, Jørn Skavland, Bjørn Tore Gjertsen, Håkon Reikvam & Øystein Bruserud
Pages: 639-653
Published online: 22 Jun 2018
AbstractforTwo acute myeloid leukemia patient subsets are identified based on the constitutive PI3K-Akt-mTOR signaling of their leukemic cells; a functional, proteomic, and transcriptomic comparison | Full Text | References | PDF (2 MB) | Supplemental
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