Expert Opinion on Therapeutic Targets, Volume 23, Issue 4 (2019)

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Expert Opinion on Therapeutic Targets, Volume 23, Issue 4 (2019)

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Editorial

Article
The emergence of Ephexin5 as a therapeutic target in Alzheimer’s disease
Emily K. Cook, Gabrielle L. Sell, Thomas B. Schaffer & Seth S. Margolis
Pages: 263-265
Published online: 05 Mar 2019
First Page PreviewforThe emergence of Ephexin5 as a therapeutic target in Alzheimer’s disease | Full Text | References | PDF (446.8 KB) | EPUB
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Review

Article
Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview
Tyler S. McCann, Lays M. Sobral, Chelsea Self, Joseph Hsieh, Marybeth Sechler & Paul Jedlicka
Pages: 267-280
Published online: 26 Feb 2019
AbstractforBiology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview | Full Text | References | PDF (1 MB) | EPUB
  • 294 Views
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Article
The NKG2D axis: an emerging target in cancer immunotherapy
Mariya Lazarova & Alexander Steinle
Pages: 281-294
Published online: 22 Feb 2019
AbstractforThe NKG2D axis: an emerging target in cancer immunotherapy | Full Text | References | PDF (1.6 MB) | EPUB
  • 1244 Views
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Review
Tumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target
Juliane Medler & Harald Wajant
Pages: 295-307
Published online: 19 Mar 2019
AbstractforTumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target | Full Text | References | PDF (1.8 MB) | EPUB
  • 3385 Views
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Article
Th17 cells: a promising therapeutic target for Parkinson’s disease?
Iryna Prots & Beate Winner
Pages: 309-314
Published online: 14 Mar 2019
AbstractforTh17 cells: a promising therapeutic target for Parkinson’s disease? | Full Text | References | PDF (522 KB) | EPUB
  • 377 Views
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Article
Current strategies toward safer mu opioid receptor drugs for pain management
Aliza T. Ehrlich, Brigitte L. Kieffer & Emmanuel Darcq
Pages: 315-326
Published online: 15 Mar 2019
AbstractforCurrent strategies toward safer mu opioid receptor drugs for pain management | Full Text | References | PDF (2 MB) | EPUB
  • 1018 Views
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Article
Agmatine as a potential therapeutic intervention in bipolar depression: the preclinical landscape
Devon Watts, Bianca Pfaffenseller, Bianca Wollenhaupt-Aguiar, Luiza Paul Géa, Taiane De Azevedo Cardoso & Flavio Kapczinski
Pages: 327-339
Published online: 22 Feb 2019
AbstractforAgmatine as a potential therapeutic intervention in bipolar depression: the preclinical landscape | Full Text | References | PDF (1.7 MB) | EPUB
  • 381 Views
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Article
Targeting metabotropic glutamate receptors in the treatment of epilepsy: rationale and current status
Roberta Celli, Ines Santolini, Gilles Van Luijtelaar, Richard T Ngomba, Valeria Bruno & Ferdinando Nicoletti
Pages: 341-351
Published online: 21 Mar 2019
AbstractforTargeting metabotropic glutamate receptors in the treatment of epilepsy: rationale and current status | Full Text | References | PDF (977.9 KB) | EPUB
  • 534 Views
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Original Research

Article
The use of LP533401 as a therapeutic option for renal osteodystrophy affects, renal calcium handling, vitamin D metabolism, and bone health in uremic rats
Dariusz Pawlak, Tomasz Domaniewski, Beata Znorko & Krystyna Pawlak
Pages: 353-364
Published online: 12 Mar 2019
AbstractforThe use of LP533401 as a therapeutic option for renal osteodystrophy affects, renal calcium handling, vitamin D metabolism, and bone health in uremic rats | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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