Expert Opinion on Therapeutic Targets, Volume 24, Issue 4 (2020)

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Expert Opinion on Therapeutic Targets, Volume 24, Issue 4 (2020)

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Editorial

Editorial
Desmoplastic small round cell tumor (DSRCT): emerging therapeutic targets and future directions for potential therapies
Anastasia Loktev & Janet M. Shipley
Pages: 281-285
Published online: 11 Mar 2020
First Page PreviewforDesmoplastic small round cell tumor (DSRCT): emerging therapeutic targets and future directions for potential therapies | Full Text | References | PDF (795 KB) | EPUB
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Review

Review
Glucocerebrosidase as a therapeutic target for Parkinson’s disease
Yu Chen, Richard Sam, Pankaj Sharma, Lu Chen, Jenny Do & Ellen Sidransky
Pages: 287-294
Published online: 27 Feb 2020
AbstractforGlucocerebrosidase as a therapeutic target for Parkinson’s disease | Full Text | References | PDF (1,019.3 KB) | EPUB
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Review
Silence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS)
Elena Abati, Nereo Bresolin, Giacomo Comi & Stefania Corti
Pages: 295-310
Published online: 14 Mar 2020
AbstractforSilence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS) | Full Text | References | PDF (1.4 MB) | EPUB
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Review
FGF2: a novel druggable target for glioblastoma?
Ana Jimenez-Pascual, Kelly Mitchell, Florian A Siebzehnrubl & Justin D Lathia
Pages: 311-318
Published online: 16 Mar 2020
AbstractforFGF2: a novel druggable target for glioblastoma? | Full Text | References | PDF (1,003.5 KB) | EPUB
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Review
Alzheimer’s disease: phenotypic approaches using disease models and the targeting of tau protein
Elisabetta Lauretti & Domenico Praticò
Pages: 319-330
Published online: 06 Mar 2020
AbstractforAlzheimer’s disease: phenotypic approaches using disease models and the targeting of tau protein | Full Text | References | PDF (1.2 MB) | EPUB
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Review
Alzheimer’s disease: microglia targets and their modulation to promote amyloid phagocytosis and mitigate neuroinflammation
Shehata Anwar & Serge Rivest
Pages: 331-344
Published online: 12 Mar 2020
AbstractforAlzheimer’s disease: microglia targets and their modulation to promote amyloid phagocytosis and mitigate neuroinflammation | Full Text | References | PDF (1.2 MB) | EPUB
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Review
Cholangiocarcinoma: novel therapeutic targets
Keisaku Sato, Shannon Glaser, Domenico Alvaro, Fanyin Meng, Heather Francis & Gianfranco Alpini
Pages: 345-357
Published online: 26 Feb 2020
AbstractforCholangiocarcinoma: novel therapeutic targets | Full Text | References | PDF (1.3 MB) | EPUB
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Review
Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment
Saeed Mehrzadi, Karim Hemati, Russel J. Reiter & Azam Hosseinzadeh
Pages: 359-378
Published online: 02 Mar 2020
AbstractforMitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment | Full Text | References | PDF (1.8 MB) | EPUB
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Original Research

Article
Prevention of DMBA-induced mammary gland tumors in mice by a dual-function inhibitor of JAK3 and EGF receptor tyrosine kinases
Kazim Sahin, Mehmet Yabas, Cemal Orhan, Mehmet Tuzcu, Taha K. Sahin, Ibrahim H. Ozercan, Sanjive Qazi & Fatih M. Uckun
Pages: 379-387
Published online: 02 Mar 2020
AbstractforPrevention of DMBA-induced mammary gland tumors in mice by a dual-function inhibitor of JAK3 and EGF receptor tyrosine kinases | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Cepharanthine hydrochloride induces mitophagy targeting GPR30 in hepatocellular carcinoma (HCC)
Yao Wang, Gui-Feng Su, Ze-Xiu Huang, Zhen-Guang Wang, Peng-Jun Zhou, Jiang-Lin Fan & Yi-Fei Wang
Pages: 389-402
Published online: 14 Mar 2020
AbstractforCepharanthine hydrochloride induces mitophagy targeting GPR30 in hepatocellular carcinoma (HCC) | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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