Expert Opinion on Therapeutic Targets, Volume 26, Issue 4 (2022)

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Expert Opinion on Therapeutic Targets, Volume 26, Issue 4 (2022)

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Review

Targeting calcium-mediated inter-organellar crosstalk in cardiac diseases
Mohit M. Hulsurkar, Satadru K. Lahiri, Jason Karch, Meng C. Wang & Xander H.T. Wehrens
Pages: 303-317
Published online: 25 Apr 2022
AbstractforTargeting calcium-mediated inter-organellar crosstalk in cardiac diseases | Full Text | References | PDF (3.7 MB) | EPUB
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Targeting SHP2 phosphatase in hematological malignancies
Rahul Kanumuri, Santhosh Kumar Pasupuleti, Sarah S Burns, Baskar Ramdas & Reuben Kapur
Pages: 319-332
Published online: 03 May 2022
AbstractforTargeting SHP2 phosphatase in hematological malignancies | Full Text | References | PDF (5.4 MB) | EPUB
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Open Access
Tenosynovial giant cell tumors (TGCT): molecular biology, drug targets and non-surgical pharmacological approaches
Geert Spierenburg, Lizz van der Heijden, Kirsten van Langevelde, Karoly Szuhai, Judith V.G.M. Bovée, Michiel A.J. van de Sande & Hans Gelderblom
Pages: 333-345
Published online: 27 Apr 2022
AbstractforTenosynovial giant cell tumors (TGCT): molecular biology, drug targets and non-surgical pharmacological approaches | Full Text | References | PDF (3.3 MB) | EPUB
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Open Access
Targeting fetal hemoglobin expression to treat β hemoglobinopathies
Martin H Steinberg
Pages: 347-359
Published online: 26 Apr 2022
AbstractforTargeting fetal hemoglobin expression to treat β hemoglobinopathies | Full Text | References | PDF (1.9 MB) | EPUB
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The brain heme oxygenase/biliverdin reductase system as a target in drug research and development
Cesare Mancuso
Pages: 361-374
Published online: 16 Mar 2022
AbstractforThe brain heme oxygenase/biliverdin reductase system as a target in drug research and development | Full Text | References | PDF (1.1 MB) | EPUB
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Original Research

Article
Curcumin analog, GO-Y078, induces HO-1 transactivation-mediated apoptotic cell death of oral cancer cells by triggering MAPK pathways and AP-1 DNA-binding activity
Ming-Hsien Chien, Pei-Chun Shih, Yi-Fang Ding, Li-Hsin Chen, Feng-Koo Hsieh, Meng-Ying Tsai, Pei-Yi Li, Chiao-Wen Lin & Shun-Fa Yang
Pages: 375-388
Published online: 05 Apr 2022
AbstractforCurcumin analog, GO-Y078, induces HO-1 transactivation-mediated apoptotic cell death of oral cancer cells by triggering MAPK pathways and AP-1 DNA-binding activity | Full Text | References | PDF (5.8 MB) | EPUB | Supplemental
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