Expert Opinion on Therapeutic Targets, Volume 27, Issue 4-5 (2023)

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Expert Opinion on Therapeutic Targets, Volume 27, Issue 4-5 (2023)

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Editorial

Editorial
Virus-induced senescence: A therapeutic target to mitigate severe progression of SARS-COV-2
Mani Iyer Prasanth, James Michael Brimson & Tewin Tencomnao
Pages: 263-267
Published online: 27 May 2023
First Page PreviewforVirus-induced senescence: A therapeutic target to mitigate severe progression of SARS-COV-2 | Full Text | References | PDF (4.4 MB) | EPUB
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Review

Review Article
Focusing on oligomeric tau as a therapeutic target in Alzheimer’s disease and other tauopathies
Joseph B. Rayman
Pages: 269-279
Published online: 04 May 2023
AbstractforFocusing on oligomeric tau as a therapeutic target in Alzheimer’s disease and other tauopathies | Full Text | References | PDF (324 KB) | EPUB
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Open Access
Review Article
Emerging therapeutic targets for anorexia nervosa
Andreas Stengel & Katrin Giel
Pages: 281-292
Published online: 28 Apr 2023
AbstractforEmerging therapeutic targets for anorexia nervosa | Full Text | References | PDF (324.3 KB) | EPUB
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Review Article
Toxoplasma gondii infection: novel emerging therapeutic targets
Joachim Müller & Andrew Hemphill
Pages: 293-304
Published online: 24 May 2023
AbstractforToxoplasma gondii infection: novel emerging therapeutic targets | Full Text | References | PDF (12.2 MB) | EPUB
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Review Article
Targeting the EGFR signaling pathway in cancer therapy: What’s new in 2023?
Sushanta Halder, Soumi Basu, Shobhit P. Lall, Apar K. Ganti, Surinder K. Batra & Parthasarathy Seshacharyulu
Pages: 305-324
Published online: 02 Jun 2023
AbstractforTargeting the EGFR signaling pathway in cancer therapy: What’s new in 2023? | Full Text | References | PDF (5.7 MB) | EPUB
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Review Article
Renal ciliopathies: promising drug targets and prospects for clinical trials
Laura Devlin, Praveen Dhondurao Sudhindar & John A. Sayer
Pages: 325-346
Published online: 05 Jun 2023
AbstractforRenal ciliopathies: promising drug targets and prospects for clinical trials | Full Text | References | PDF (2.3 MB) | EPUB
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Open Access
Review Article
Bruton’s tyrosine kinase as a promising therapeutic target for multiple sclerosis
Darius Saberi, Anastasia Geladaris, Sarah Dybowski & Martin S. Weber
Pages: 347-359
Published online: 05 Jun 2023
AbstractforBruton’s tyrosine kinase as a promising therapeutic target for multiple sclerosis | Full Text | References | PDF (1.8 MB) | EPUB
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Original Research

Article
Novel chromobox 2 inhibitory peptide decreases tumor progression
Lindsay W. Brubaker, Donald S. Backos, Vu T. Nguyen, Philip Reigan, Tomomi M Yamamoto, Elizabeth R. Woodruff, Ritsuko Iwanaga, Michael F. Wempe, Vijay Kumar, Christianne Persenaire, Zachary L. Watson & Benjamin G. Bitler
Pages: 361-371
Published online: 27 May 2023
AbstractforNovel chromobox 2 inhibitory peptide decreases tumor progression | Full Text | References | PDF (8.7 MB) | EPUB | Supplemental
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Article
Dapagliflozin modulates neuronal injury via instigation of LKB1/p-AMPK/GABAB R2 signaling pathway and suppression of the inflammatory cascade in an essential tremor rat model
Ahmed S. Kamel, Sama M. Farrag, Heba M. Mansour, Noha N. Nassar & Muhammed A. Saad
Pages: 373-392
Published online: 02 May 2023
AbstractforDapagliflozin modulates neuronal injury via instigation of LKB1/p-AMPK/GABAB R2 signaling pathway and suppression of the inflammatory cascade in an essential tremor rat model | Full Text | References | PDF (10.2 MB) | EPUB
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Article
The lncRNA OIP5-AS1/miR-4500 axis targeting ARG2 modulates oxidative stress-induced premature senescence in endothelial cells: implications for vascular aging
Yajun Wang, Yang Li, Yirong Li, Yue Cui, Yan Zhang, Wenzhen Shi, Jiangxia Wang, Xiaopeng Wu, Rongrong Liang, Xin Wang, Adi Zheng, Yi Yu & Yuyan Xiong
Pages: 393-407
Published online: 26 May 2023
AbstractforThe lncRNA OIP5-AS1/miR-4500 axis targeting ARG2 modulates oxidative stress-induced premature senescence in endothelial cells: implications for vascular aging | Full Text | References | PDF (15.5 MB) | EPUB | Supplemental
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