Hemoglobin, Volume 32, Issue 6 (2008)

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Hemoglobin, Volume 32, Issue 6 (2008)

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Original Article

Article
Prenatal Diagnosis of Sickle Cell Anemia and β-Thalassemia in Southern Turkey
M. Akif Çürük, Filiz Zeren, Ahmet Genç, Sezen Ozavci-Aygün, Yurdanur Kilinç & Kiymet Aksoy
Pages: 525-530
Published online: 07 Jul 2009
AbstractforPrenatal Diagnosis of Sickle Cell Anemia and β-Thalassemia in Southern Turkey | Full Text | References | PDF (127.1 KB)
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Article
Knowledge and Attitude Toward the Hemoglobinopathies Premarital Screening Program in Saudi Arabia: Population-Based Survey
Ayman Al Sulaiman, Ahmed Suliman, May Al Mishari, Aziza Al Sawadi & Tarek M. Owaidah
Pages: 531-538
Published online: 07 Jul 2009
AbstractforKnowledge and Attitude Toward the Hemoglobinopathies Premarital Screening Program in Saudi Arabia: Population-Based Survey | Full Text | References | PDF (70.4 KB)
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Article
Prenatal Diagnosis for β-Thalassemia Major in the Iranian Province of Hormozgan
Pooneh Nikuei, Valeh Hadavi, Minoo Rajaei, Mozhgan Saberi, Fozieh Hajizade & Hossein Najmabadi
Pages: 539-545
Published online: 07 Jul 2009
AbstractforPrenatal Diagnosis for β-Thalassemia Major in the Iranian Province of Hormozgan | Full Text | References | PDF (67.6 KB)
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Article
α-Thalassemia Mutations in Khuzestan Province, Southwest Iran
Khodamorad Zandian, Jamal Nateghi, Bijan Keikhaie, Mohammad Pedram, Nima Hafezi-Nejad, Valeh Hadavi, Christian Oberkanins, Azita Azarkeivan, Hai-Yang Law & Hossein Najmabadi
Pages: 546-552
Published online: 07 Jul 2009
Abstractforα-Thalassemia Mutations in Khuzestan Province, Southwest Iran | Full Text | References | PDF (77.5 KB)
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Article
Molecular Prenatal Diagnosis of α-Thalassemia Using Real-Time and Multiplex Polymerase Chain Reaction Methods
Jing-Zhong Liu, Mei Yan, Li-Rong Wang, Zhan-Yong Wang, Yin-Ping Fan, Bai Xiao & Yan Zhou
Pages: 553-560
Published online: 07 Jul 2009
AbstractforMolecular Prenatal Diagnosis of α-Thalassemia Using Real-Time and Multiplex Polymerase Chain Reaction Methods | Full Text | References | PDF (1.3 MB)
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Article
Detection of α-Thalassemia in China by Using Multiplex Ligation-Dependent Probe Amplification
Jing-Zhong Liu, Han Han, Jan P. Schouten, Li-Rong Wang, Xin-Ping Fan, Helena B. Duarte, Chun-Jiang Zhu, Ren Cai, Bai Xiao & Qing-Tao Wang
Pages: 561-571
Published online: 07 Jul 2009
AbstractforDetection of α-Thalassemia in China by Using Multiplex Ligation-Dependent Probe Amplification | Full Text | References | PDF (1.2 MB)
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Article
The 5′ Regulatory Region of the Human Fetal Globin Genes is a Gene Conversion Hotspot
Angelos Kalamaras, Christos Chassanidis, Maria Samara, Ioanna Chiotoglou, Nikolaos K. Vamvakopoulos, Manoussos N. Papadakis, Panagoula Kollia*George P. Patrinos
Pages: 572-581
Published online: 07 Jul 2009
AbstractforThe 5′ Regulatory Region of the Human Fetal Globin Genes is a Gene Conversion Hotspot | Full Text | References | PDF (506.4 KB)
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Short Communications

Article
Hb Hinwil [β38(C4)Thr→Asn, ACC>AAC] Associated with β0-Thalassemia in a Sicilian Child
Liana Cuccia, Laura Saieva, Zelia Borsellino, Maria R. Marocco, Giovan B. Ruffo, Jean Riou & Marcello Capra
Pages: 582-587
Published online: 07 Jul 2009
AbstractforHb Hinwil [β38(C4)Thr→Asn, ACC>AAC] Associated with β0-Thalassemia in a Sicilian Child | Full Text | References | PDF (446.3 KB)
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Article
Two New Hemoglobin Variants: Hb Sinai-Greenspring [β34(B16)Val→Ile, GTC > ATC] and Hb Sinai-Bel Air [β53(D4)Ala→Asp, GCT > GAT]
Erin Dainer, Robert E. Wenk, Ruth Luddy, Dedrey Elam, Leslie Holley, Abdullah Kutlar & Ferdane Kutlar
Pages: 588-591
Published online: 07 Jul 2009
AbstractforTwo New Hemoglobin Variants: Hb Sinai-Greenspring [β34(B16)Val→Ile, GTC > ATC] and Hb Sinai-Bel Air [β53(D4)Ala→Asp, GCT > GAT] | Full Text | References | PDF (278.9 KB)
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Article
Association of Mild and Severely Unstable α Chain Variants: The First Observation of a Compound Heterozygote with Hb Setif [α94(G1)Asp→Tyr (α2)] and Hb Agrinio [α29(B10)Leu→Pro (α2)] in a Greek Family
Varvara Douna, Ioannis Papassotiriou, Alexandra Stamoulakatou, Anna Metaxotou-Mavrommati, Emmanuel Kanavakis & Joanne Traeger-Synodinos
Pages: 592-595
Published online: 07 Jul 2009
AbstractforAssociation of Mild and Severely Unstable α Chain Variants: The First Observation of a Compound Heterozygote with Hb Setif [α94(G1)Asp→Tyr (α2)] and Hb Agrinio [α29(B10)Leu→Pro (α2)] in a Greek Family | Full Text | References | PDF (64.1 KB)
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Article
Neonatal Cyanosis Due to a Novel Fetal Hemoglobin: Hb F-Circleville [Gγ63(E7)His→Leu, CAT>CTT]
Erin Dainer, Richard Shell, Randy Miller, Joan F. Atkin, Matt Pastore, Abdullah Kutlar, Lina Zhuang, Leslie Holley, Debra H. Davis & Ferdane Kutlar
Pages: 596-600
Published online: 07 Jul 2009
AbstractforNeonatal Cyanosis Due to a Novel Fetal Hemoglobin: Hb F-Circleville [Gγ63(E7)His→Leu, CAT>CTT] | Full Text | References | PDF (124.3 KB)
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Letter to the Editor

Letter
Ethical Issues and Risk/Benefit Assessment of Iron Chelation Therapy: Advances with Deferiprone/deferoxamine Combinations and Concerns about the Safety, Efficacy and Costs of Deferasirox [Kontoghiorghes GJ, Hemoglobin 2008; 32(1–2):1–15.]
John B. Porter, Ali T. Taher, Maria D. Cappellini & Elliott P. Vichinsky
Pages: 601-607
Published online: 07 Jul 2009
First Page PreviewforEthical Issues and Risk/Benefit Assessment of Iron Chelation Therapy: Advances with Deferiprone/deferoxamine Combinations and Concerns about the Safety, Efficacy and Costs of Deferasirox [Kontoghiorghes GJ, Hemoglobin 2008; 32(1–2):1–15.] | Full Text | References | PDF (69.4 KB)
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Free Access

Response to the Letter to the Editor

Letter
Transparency and Access to Full Information for the Fatal or Serious Toxicity Risks, Low Efficacy and High Price of Deferasirox, Could Increase the Prospect of Improved Iron Chelation Therapy Worldwide
George J. Kontoghiorghes
Pages: 608-615
Published online: 07 Jul 2009
First Page PreviewforTransparency and Access to Full Information for the Fatal or Serious Toxicity Risks, Low Efficacy and High Price of Deferasirox, Could Increase the Prospect of Improved Iron Chelation Therapy Worldwide | Full Text | References | PDF (321.6 KB)
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