Leukemia & Lymphoma, Volume 54, Issue 3 (2013)

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Leukemia & Lymphoma, Volume 54, Issue 3 (2013)

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Commentaries on selected articles in this issue

Article Commentary
“Primum non nocere”: the addition of granulocyte-macrophage colony stimulating factor to alemtuzumab in chronic lymphocytic leukemia
Daphne R. Friedman
Pages: 441-442
Published online: 28 Sep 2012
Citationfor“Primum non nocere”: the addition of granulocyte-macrophage colony stimulating factor to alemtuzumab in chronic lymphocytic leukemia | Full Text | References | PDF (131.6 KB) | Supplemental
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Commentary

Article Commentary
Tackling Burkitt lymphoma in older patients: novel strategies and the promise of targeted agents
Catherine Lai & Kieron Dunleavy
Pages: 443-444
Published online: 02 Jan 2013
CitationforTackling Burkitt lymphoma in older patients: novel strategies and the promise of targeted agents | Full Text | References | PDF (131.8 KB) | Supplemental
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Article Commentary
Radiotherapy in orbital lymphoma: optimizing the backbone to build upon
Hang Quach & Sidney Davis
Pages: 445-446
Published online: 01 Oct 2012
CitationforRadiotherapy in orbital lymphoma: optimizing the backbone to build upon | Full Text | References | PDF (135.8 KB) | Supplemental
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Article Commentary
Searching for clarity in therapy-related myelodysplastic syndrome/acute myeloid leukemia prognostication
Sarah E. Fordham, Helen Marr & James M. Allan
Pages: 447-448
Published online: 28 Sep 2012
CitationforSearching for clarity in therapy-related myelodysplastic syndrome/acute myeloid leukemia prognostication | Full Text | References | PDF (132.4 KB) | Supplemental
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Article Commentary
Cryptococcosis, lymphoproliferative disorders and modern day chemotherapy regimens
Monica A. Slavin & Sharon C.-A. Chen
Pages: 449-450
Published online: 02 Jan 2013
CitationforCryptococcosis, lymphoproliferative disorders and modern day chemotherapy regimens | Full Text | References | PDF (135.8 KB) | Supplemental
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Reviews

Review Article
Evolving therapeutic paradigms for multiple myeloma: back to the future
Benjamin M. Cherry, Neha Korde, Mary Kwok, Mark Roschewski & Ola Landgren
Pages: 451-463
Published online: 14 Sep 2012
AbstractforEvolving therapeutic paradigms for multiple myeloma: back to the future | Full Text | References | PDF (332.9 KB) | Supplemental
  • 688 Views
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Review Article

Review Article
Waldenström macroglobulinemia: my way
Morie Gertz
Pages: 464-471
Published online: 25 Aug 2012
AbstractforWaldenström macroglobulinemia: my way | Full Text | References | PDF (326.8 KB) | Supplemental
  • 1106 Views
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Review Article
Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group
Arjan A. van de Loosdrecht, Robin Ireland, Wolfgang Kern, Matteo G. Della Porta, Canan Alhan, Jan Sebastian Balleisen, Peter Bettelheim, David T. Bowen, Kate Burbury, Lisa Eidenschink, Mario Cazzola, Spencer S. C. Chu, Matthew Cullen, Jevon A. Cutler, Angelika M. Dräger, Jean Feuillard, Pierre Fenaux, Patricia Font, Ulrich Germing, Detlef Haase, Eva Hellström-Lindberg, Ulrika Johansson, Shahram Kordasti, Michael R. Loken, Luca Malcovati, Jeroen G. te Marvelde, Sergio Matarraz, Timothy Milne, Bijan Moshaver, Ghulam J. Mufti, Veselka Nikolova, Kiyoyuki Ogata, Uta Oelschlaegel, Alberto Orfao, Gert J. Ossenkoppele, Anna Porwit, Uwe Platzbecker, Frank Preijers, Katherina Psarra, Stephen J. Richards, Dolores Subirá, John F. Seymour, Vicky Tindell, Teresa Vallespi, Peter Valent, Vincent H. J. van der Velden, Denise A. Wells, Theo M. de Witte, Florian Zettl, Marie C. Béné & Theresia M. Westers
Pages: 472-475
Published online: 14 Sep 2012
AbstractforRationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group | Full Text | References | PDF (165.2 KB) | Supplemental
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Original Articles: Clinical

Article
Addition of granulocyte macrophage colony stimulating factor does not improve response to early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab
Clive S. Zent, Wenting Wu, Deborah A. Bowen, Curtis A. Hanson, Adam M. Pettinger, Tait D. Shanafelt, Neil E. Kay, Jose F. Leis & Timothy G. Call
Pages: 476-482
Published online: 22 Aug 2012
AbstractforAddition of granulocyte macrophage colony stimulating factor does not improve response to early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab | Full Text | References | PDF (273.2 KB) | Supplemental
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Research Article

Article
Brief intensive therapy for older adults with newly diagnosed Burkitt or atypical Burkitt lymphoma/leukemia
Yvette L. Kasamon, Robert A. Brodsky, Michael J. Borowitz, Richard F. Ambinder, Pamela A. Crilley, Steve Y. Cho, Hua-ling Tsai, B. Douglas Smith, Douglas E. Gladstone, Hetty E. Carraway, Carol Ann Huff, William H. Matsui, Javier Bolaños-Meade, Richard J. Jones & Lode J. Swinnen
Pages: 483-490
Published online: 17 Aug 2012
AbstractforBrief intensive therapy for older adults with newly diagnosed Burkitt or atypical Burkitt lymphoma/leukemia | Full Text | References | PDF (265.3 KB) | Supplemental
  • 528 Views
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Article
Efficacy of low dose radiotherapy for primary orbital marginal zone lymphoma
Krystel H. Tran, Belinda A. Campbell, Tsien Fua, Michael MacManus, Gail Ryan, Brent Chesson & Andrew Wirth
Pages: 491-496
Published online: 28 Sep 2012
AbstractforEfficacy of low dose radiotherapy for primary orbital marginal zone lymphoma | Full Text | References | PDF (250.7 KB) | Supplemental
  • 586 Views
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Article
Bortezomib may be safely combined with Y-90-ibritumomab tiuxetan in patients with relapsed/refractory follicular non-Hodgkin lymphoma: a phase I trial of combined induction therapy and bortezomib consolidation
Rupali Roy, Andrew M. Evens, David Patton, Lillia Gallot, Annette Larson, Alfred Rademaker, Jeffrey Cilley, Stewart Spies, Daina Variakojis, Leo I. Gordon & Jane N. Winter
Pages: 497-502
Published online: 11 Sep 2012
AbstractforBortezomib may be safely combined with Y-90-ibritumomab tiuxetan in patients with relapsed/refractory follicular non-Hodgkin lymphoma: a phase I trial of combined induction therapy and bortezomib consolidation | Full Text | References | PDF (213.3 KB) | Supplemental
  • 261 Views
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Article
Intrathecal therapy with rituximab in central nervous system involvement of post-transplant lymphoproliferative disorder
Krzysztof Czyzewski, Jan Styczynski, Anna Krenska, Robert Debski, Olga Zajac-Spychala, Jacek Wachowiak & Mariusz Wysocki
Pages: 503-506
Published online: 31 Aug 2012
AbstractforIntrathecal therapy with rituximab in central nervous system involvement of post-transplant lymphoproliferative disorder | Full Text | References | PDF (180.4 KB) | Supplemental
  • 1327 Views
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Article
Treatment response and overall outcome of patients with relapsed and refractory peripheral T-cell lymphoma compared to diffuse large B-cell lymphoma
Noemi Puig, Lisa Wang, Tara Seshadri, Khalil al-Farsi, Armand Keating, Michael Crump & John Kuruvilla
Pages: 507-513
Published online: 08 Sep 2012
AbstractforTreatment response and overall outcome of patients with relapsed and refractory peripheral T-cell lymphoma compared to diffuse large B-cell lymphoma | Full Text | References | PDF (256.4 KB) | Supplemental
  • 429 Views
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Article
Efficacy and safety of denileukin diftitox retreatment in patients with relapsed cutaneous T-cell lymphoma
Madeleine Duvic, Ann G. Martin, Elise A. Olsen, David P. Fivenson & H. Miles Prince
Pages: 514-519
Published online: 03 Sep 2012
AbstractforEfficacy and safety of denileukin diftitox retreatment in patients with relapsed cutaneous T-cell lymphoma | Full Text | References | PDF (223.4 KB) | Supplemental
  • 376 Views
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Article
Combination of skin-directed therapy and oral etoposide for smoldering adult T-cell leukemia/lymphoma with skin involvement
Yu Sawada, Takatoshi Shimauchi, Takashi Yamaguchi, Risa Okura, Kayo Hama-Yamamoto, Haruna Fueki-Yoshioka, Shun Ohmori, Shigenori Yamada, Mayuko Yoshizawa, Kana Hiromasa, Makiko Tajiri, Rieko Kabashima-Kubo, Manabu Yoshioka, Kazunari Sugita, Ryutaro Yoshiki, Ryosuke Hino, Miwa Kobayashi, Kunio Izu, Motonobu Nakamura & Yoshiki Tokura
Pages: 520-527
Published online: 21 Aug 2012
AbstractforCombination of skin-directed therapy and oral etoposide for smoldering adult T-cell leukemia/lymphoma with skin involvement | Full Text | References | PDF (380.5 KB) | Supplemental
  • 218 Views
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Article
Correlation of the microculture-kinetic drug-induced apoptosis assay with patient outcomes in initial treatment of adult acute myelocytic leukemia
Stephen A. Strickland, Anastasios Raptis, Allan Hallquist, James Rutledge, Michael Chernick, Mathieu Perree, Mahsa S. Talbott & Cary A. Presant
Pages: 528-534
Published online: 17 Sep 2012
AbstractforCorrelation of the microculture-kinetic drug-induced apoptosis assay with patient outcomes in initial treatment of adult acute myelocytic leukemia | Full Text | References | PDF (244.3 KB) | Supplemental
  • 176 Views
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Article
Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia
Kevin R. Krull, Marilyn J. Hockenberry, Petra Miketova, Marissa Carey & Ida M. Moore
Pages: 535-540
Published online: 30 Aug 2012
AbstractforChemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia | Full Text | References | PDF (233.5 KB) | Supplemental
  • 385 Views
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Article
Influence of obesity on efficacy and toxicity of induction chemotherapy in patients with newly diagnosed acute myeloid leukemia
Andrew Lin, Megan Othus, Amy McQuary, Mary Chi & Elihu Estey
Pages: 541-546
Published online: 22 Aug 2012
AbstractforInfluence of obesity on efficacy and toxicity of induction chemotherapy in patients with newly diagnosed acute myeloid leukemia | Full Text | References | PDF (265 KB) | Supplemental
  • 452 Views
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Article
Outcome of risk adapted therapy for relapsed/refractory acute lymphoblastic leukemia in children
Asim F. Belgaumi, Amal Al-Seraihy, Khawar S. Siddiqui, Mouhab Ayas, Asem Bukhari, Abdulrahman Al-Musa, Ali Al-Ahmari & Hassan El-Solh
Pages: 547-554
Published online: 18 Oct 2012
AbstractforOutcome of risk adapted therapy for relapsed/refractory acute lymphoblastic leukemia in children | Full Text | References | PDF (338.8 KB) | Supplemental
  • 296 Views
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Article
Lenalidomide (Revlimid), bortezomib (Velcade) and dexamethasone for heavily pretreated relapsed or refractory multiple myeloma
Victor H. Jimenez-Zepeda, Donna E. Reece, Suzanne Trudel, Christine Chen, Rodger Tiedemann & Vishal Kukreti
Pages: 555-560
Published online: 02 Jan 2013
AbstractforLenalidomide (Revlimid), bortezomib (Velcade) and dexamethasone for heavily pretreated relapsed or refractory multiple myeloma | Full Text | References | PDF (257.5 KB) | Supplemental
  • 1555 Views
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Original Articles: Research

Article
Telomerase inhibition by non-nucleosidic compound BIBR1532 causes rapid cell death in pre-B acute lymphoblastic leukemia cells
Davood Bashash, Seyed H. Ghaffari, Rooholah Mirzaee, Kamran Alimoghaddam & Ardeshir Ghavamzadeh
Pages: 561-568
Published online: 28 Sep 2012
AbstractforTelomerase inhibition by non-nucleosidic compound BIBR1532 causes rapid cell death in pre-B acute lymphoblastic leukemia cells | Full Text | References | PDF (392.4 KB) | Supplemental
  • 418 Views
  • 27 CrossRef citations
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Research Article

Article
Degree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2
Laura N. Eadie, Verity A. Saunders, Timothy P. Hughes & Deborah L. White
Pages: 569-578
Published online: 21 Aug 2012
AbstractforDegree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2 | Full Text | References | PDF (753.9 KB) | Supplemental
  • 312 Views
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Article
Quantitative detection of zeta-chain-associated protein 70 expression in chronic lymphocytic leukemia
Peixuan Zhu, Heba A. Degheidy, Gerald E. Marti, Shuhong Li, Fatima Abbasi, Adrian Wiestner, Platte Amstutz & Cha-Mei Tang
Pages: 579-586
Published online: 14 Aug 2012
AbstractforQuantitative detection of zeta-chain-associated protein 70 expression in chronic lymphocytic leukemia | Full Text | References | PDF (572.4 KB) | Supplemental
  • 113 Views
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Article
Interleukin-24 mediates apoptosis in human B-cells through early activation of cell cycle arrest followed by late induction of the mitochondrial apoptosis pathway
Nader Hadife, Christophe Nemos, Jean-Pol Frippiat, Tala Hamadé, Aurore Perrot & Ali Dalloul
Pages: 587-597
Published online: 30 Aug 2012
AbstractforInterleukin-24 mediates apoptosis in human B-cells through early activation of cell cycle arrest followed by late induction of the mitochondrial apoptosis pathway | Full Text | References | PDF (619.1 KB) | Supplemental
  • 293 Views
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Article
Early detection and quantification of mutations in the tyrosine kinase domain of chimerical BCR–ABL1 gene combining high-resolution melting analysis and mutant-allele specific quantitative polymerase chain reaction
Cristian Ferri, Michele Bianchini, Gustavo Icardi, Carolina Belli, Raquel Bengió & Irene Larripa
Pages: 598-606
Published online: 31 Aug 2012
AbstractforEarly detection and quantification of mutations in the tyrosine kinase domain of chimerical BCR–ABL1 gene combining high-resolution melting analysis and mutant-allele specific quantitative polymerase chain reaction | Full Text | References | PDF (2 MB) | Supplemental
  • 239 Views
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Article
Norcantharidin enhances bortezomib-antimyeloma activity in multiple myeloma cells in vitro and in nude mouse xenografts
Heng-Fei Du, Lu-Jia Yu, Yan-Feng Meng, Hong-Yan Lv, Jianbo Meng, Xiao-Ning Song & Jin-Qiao Zhang
Pages: 607-618
Published online: 03 Sep 2012
AbstractforNorcantharidin enhances bortezomib-antimyeloma activity in multiple myeloma cells in vitro and in nude mouse xenografts | Full Text | References | PDF (4.8 MB) | Supplemental
  • 208 Views
  • 6 CrossRef citations
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Article
Fas-associated phosphatase 1 mediates Fas resistance in myeloid progenitor cells expressing the Bcr–abl oncogene
Weiqi Huang, Ling Bei & Elizabeth A. Eklund
Pages: 619-630
Published online: 05 Sep 2012
AbstractforFas-associated phosphatase 1 mediates Fas resistance in myeloid progenitor cells expressing the Bcr–abl oncogene | Full Text | References | PDF (798.6 KB) | Supplemental
  • 158 Views
  • 11 CrossRef citations
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Article
Synergism between fibronectin and transforming growth factor-β1 in the production of substance P in monocytes of patients with myelofibrosis
Victor T. Chang, Clara Yook & Pranela Rameshwar
Pages: 631-638
Published online: 11 Sep 2012
AbstractforSynergism between fibronectin and transforming growth factor-β1 in the production of substance P in monocytes of patients with myelofibrosis | Full Text | References | PDF (362.5 KB) | Supplemental
  • 249 Views
  • 9 CrossRef citations
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Letters to the Editor

Letter
Patients with therapy-related myelodysplastic syndromes and acute myeloid leukemia share genetic features but can be separated by blast counts and cytogenetic risk profiles into prognostically relevant subgroups
Ulrike Bacher, Claudia Haferlach, Tamara Alpermann, Susanne Schnittger, Wolfgang Kern & Torsten Haferlach
Pages: 639-642
Published online: 21 Aug 2012
First Page PreviewforPatients with therapy-related myelodysplastic syndromes and acute myeloid leukemia share genetic features but can be separated by blast counts and cytogenetic risk profiles into prognostically relevant subgroups | Full Text | References | PDF (191.8 KB) | Supplemental
  • 269 Views
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Letter

Letter
Early cryptococcal meningitis following treatment with rituximab, fludarabine and cyclophosphamide in a patient with chronic lymphocytic leukemia
Tony Marchand, Matthieu Revest, Pierre Tattevin, Sylviane Chevrier, Elsa Poullot, Thierry Lamy & Roch Houot
Pages: 643-645
Published online: 02 Jan 2013
First Page PreviewforEarly cryptococcal meningitis following treatment with rituximab, fludarabine and cyclophosphamide in a patient with chronic lymphocytic leukemia | Full Text | References | PDF (141.4 KB) | Supplemental
  • 314 Views
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Letter
Use of plerixafor in patients with Hodgkin lymphoma with poor mobilization of peripheral blood stem cells
Shan Yuan, Auayporn Nademanee, Stephen J. Forman & Shirong Wang
Pages: 646-648
Published online: 09 Aug 2012
First Page PreviewforUse of plerixafor in patients with Hodgkin lymphoma with poor mobilization of peripheral blood stem cells | Full Text | References | PDF (138.9 KB) | Supplemental
  • 289 Views
  • 2 CrossRef citations
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Letter
An aggressive B-cell lymphoma with rearrangements of MYC and CCND1 genes: a rare subtype of double-hit lymphoma
Eric Durot, Martine Patey, Isabelle Luquet, Baptiste Gaillard, Brigitte Kolb & Alain Delmer
Pages: 649-652
Published online: 10 Sep 2012
First Page PreviewforAn aggressive B-cell lymphoma with rearrangements of MYC and CCND1 genes: a rare subtype of double-hit lymphoma | Full Text | References | PDF (242.4 KB) | Supplemental
  • 353 Views
  • 6 CrossRef citations
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Letter
Loss of BCL7A expression correlates with poor disease prognosis in patients with early-stage cutaneous T-cell lymphoma
Ivan V. Litvinov, Youwen Zhou, Thomas S. Kupper & Denis Sasseville
Pages: 653-654
Published online: 28 Aug 2012
CitationforLoss of BCL7A expression correlates with poor disease prognosis in patients with early-stage cutaneous T-cell lymphoma | Full Text | References | PDF (182.7 KB) | Supplemental
  • 279 Views
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Letter
Human leukocyte antigen-haploidentical hematopoietic stem cell transplant for a patient with histiocytic sarcoma
Amer Zeidan, Javier Bolaños-Meade, Yvette Kasamon, Joseph Aoki, Michael Borowitz, Lode Swinnen, Heather Symons, Leo Luznik, Ephraim Fuchs, Richard Jones & Richard Ambinder
Pages: 655-657
Published online: 27 Aug 2012
First Page PreviewforHuman leukocyte antigen-haploidentical hematopoietic stem cell transplant for a patient with histiocytic sarcoma | Full Text | References | PDF (292.1 KB) | Supplemental
  • 230 Views
  • 7 CrossRef citations
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Letter
High rate of remissions in chronic myelomonocytic leukemia treated with 5-azacytidine: results of an Italian retrospective study
Luana Fianchi, Marianna Criscuolo, Massimo Breccia, Luca Maurillo, Flavia Salvi, Pellegrino Musto, Giovanna Mansueto, Gianluca Gaidano, Carlo Finelli, Antonietta Aloe-Spiriti, Valeria Santini, Mariangelo Greco, Stefan Hohaus, Giuseppe Leone & Maria Teresa Voso
Pages: 658-661
Published online: 30 Aug 2012
First Page PreviewforHigh rate of remissions in chronic myelomonocytic leukemia treated with 5-azacytidine: results of an Italian retrospective study | Full Text | References | PDF (153.4 KB) | Supplemental
  • 632 Views
  • 45 CrossRef citations
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Letter
Successful disease control with l-asparaginase monotherapy for aggressive natural killer cell leukemia with severe hepatic failure
Hiroyuki Takahashi, Rika Sakai, Yukako Hattori, Rika Ohshima, Hideyuki Kuwabara, Maki Hagihara, Makiko Enaka, Akinori Nozawa, Naoto Tomita, Yoshiaki Ishigatsubo & Shin Fujisawa
Pages: 662-664
Published online: 03 Sep 2012
First Page PreviewforSuccessful disease control with l-asparaginase monotherapy for aggressive natural killer cell leukemia with severe hepatic failure | Full Text | References | PDF (204.1 KB) | Supplemental
  • 207 Views
  • 7 CrossRef citations
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Letter
Extramedullary relapse following reduced intensity allogeneic hematopoietic cell transplant for adult acute myelogenous leukemia
Neil Kogut, Ni-Chun Tsai, Sandra H. Thomas, Joycelynne Palmer, Tanya Paris, Joyce Murata-Collins & Stephen J. Forman
Pages: 665-668
Published online: 12 Sep 2012
First Page PreviewforExtramedullary relapse following reduced intensity allogeneic hematopoietic cell transplant for adult acute myelogenous leukemia | Full Text | References | PDF (219.3 KB) | Supplemental
  • 120 Views
  • 16 CrossRef citations
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Letter
The limit for chronic myeloid leukemia relapse after allogeneic hematopoietic stem cell transplant moves ever forward: when can you safely talk about healing?
Anna Paola Iori, Massimo Breccia, Corrado Girmenia, Salvatore Perrone, Veronica Valle, Fiammetta Natalino, Walter Barberi, Emilia Scalzulli, Giovanni Fernando Torelli, Maria Cristina Puzzolo & Robin Foà
Pages: 669-670
Published online: 04 Oct 2012
CitationforThe limit for chronic myeloid leukemia relapse after allogeneic hematopoietic stem cell transplant moves ever forward: when can you safely talk about healing? | Full Text | References | PDF (130.5 KB) | Supplemental
  • 110 Views
  • 1 CrossRef citations
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Letter
Somatic mutations of PHF6 in patients with chronic myeloid leukemia in blast crisis
Xianmin Li, Hong Yao, Zixing Chen, Qinrong Wang, Yun Zhao & Suning Chen
Pages: 671-672
Published online: 28 Sep 2012
CitationforSomatic mutations of PHF6 in patients with chronic myeloid leukemia in blast crisis | Full Text | References | PDF (232.9 KB) | Supplemental
  • 440 Views
  • 7 CrossRef citations
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