Leukemia & Lymphoma, Volume 62, Issue 1 (2021)

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Leukemia & Lymphoma, Volume 62, Issue 1 (2021)

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Commentaries

Article Commentary
Secondary central nervous system diffuse large cell lymphoma: an opportunity for radiation therapy to improve outcomes
Bouthaina S. Dabaja, Sarah A. Milgrom & Andrew Wirth
Pages: 1-4
Published online: 25 Dec 2020
First Page PreviewforSecondary central nervous system diffuse large cell lymphoma: an opportunity for radiation therapy to improve outcomes | Full Text | References | PDF (872.4 KB) | EPUB
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Article Commentary
FOXes at play in the lymphoma landscape
Sheren Younes & Yasodha Natkunam
Pages: 5-7
Published online: 16 Oct 2020
First Page PreviewforFOXes at play in the lymphoma landscape | Full Text | References | PDF (305.1 KB) | EPUB
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Reviews

Measurable residual disease in hematopoietic stem cell transplantation-eligible patients with acute myeloid leukemia: clinical significance and promising therapeutic strategies
Daria Gaut & Monica Mead
Pages: 8-31
Published online: 02 Nov 2020
AbstractforMeasurable residual disease in hematopoietic stem cell transplantation-eligible patients with acute myeloid leukemia: clinical significance and promising therapeutic strategies | Full Text | References | PDF (1.1 MB) | EPUB
  • 394 Views
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The triptych of mixed histiocytosis: a systematic review of 105 cases and proposed clinical classification
Arturo Bonometti & for Associazione Italiana Ricerca Istiocitosi AIRI ONLUS
Pages: 32-44
Published online: 24 Sep 2020
AbstractforThe triptych of mixed histiocytosis: a systematic review of 105 cases and proposed clinical classification | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 431 Views
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Original Articles

Article
Development of a cell-line model to mimic the pro-survival effect of nurse-like cells in chronic lymphocytic leukemia
Ishaque S. Mohammad, Ke Lin, Melanie Oates, Umair T. Khan, Jan Burger, Andrew R. Pettitt & Jianguo Zhuang
Pages: 45-57
Published online: 28 Aug 2020
AbstractforDevelopment of a cell-line model to mimic the pro-survival effect of nurse-like cells in chronic lymphocytic leukemia | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
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Open Access
Article
Initial report of a phase II study with R-FND followed by ibritumomab tiuxetan radioimmunotherapy and rituximab maintenance in patients with untreated high-risk follicular lymphoma
Felipe Samaniego, Peter McLaughlin, Sattva S. Neelapu, Lei Feng, Michelle Fanale, Loretta Nastoupil, Maria Alma Rodriguez, Barbara Pro, Erin Taylor, Fredrick B. Hagemeister & Nathan Fowler
Pages: 58-67
Published online: 14 Sep 2020
AbstractforInitial report of a phase II study with R-FND followed by ibritumomab tiuxetan radioimmunotherapy and rituximab maintenance in patients with untreated high-risk follicular lymphoma | Full Text | References | PDF (1.9 MB) | EPUB
  • 208 Views
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Article
Consolidative or palliative whole brain radiation for secondary CNS diffuse large B-Cell lymphoma
Tyler Walburn, Natalie S. Grover, Colette J. Shen, Raghuveer Ranganathan, Christopher Dittus, Anne W. Beaven, Andrew Z. Wang & Kyle Wang
Pages: 68-75
Published online: 16 Sep 2020
AbstractforConsolidative or palliative whole brain radiation for secondary CNS diffuse large B-Cell lymphoma | Full Text | References | PDF (1.3 MB) | EPUB
  • 392 Views
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Article
Higher infiltration of intratumoral CD25+ FOXP3+ lymphocytes correlates with a favorable prognosis in patients with diffuse large B-cell lymphoma
Chen Chang, Ya-Ping Chen, L. Jeffrey Medeiros, Tsai-Yun Chen & Kung-Chao Chang
Pages: 76-85
Published online: 23 Sep 2020
AbstractforHigher infiltration of intratumoral CD25+ FOXP3+ lymphocytes correlates with a favorable prognosis in patients with diffuse large B-cell lymphoma | Full Text | References | PDF (2.3 MB) | EPUB
  • 223 Views
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Article
Identification of high-risk monomorphic post-transplant lymphoproliferative disorder following solid organ transplantation
Timothy J. Voorhees, Kavya K. Kannan, Jonathan Galeotti, Natalie Grover, Rakhee Vaidya, Dominic T. Moore, Nathan D. Montgomery, Anne W. Beaven & Christopher Dittus
Pages: 86-94
Published online: 16 Sep 2020
AbstractforIdentification of high-risk monomorphic post-transplant lymphoproliferative disorder following solid organ transplantation | Full Text | References | PDF (1.8 MB) | EPUB
  • 349 Views
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Article
Frequent mutations in HLA and related genes in extranodal NK/T cell lymphomas
Chantana Polprasert, Yasuhide Takeuchi, Hideki Makishima, Kitsada Wudhikarn, Nobuyuki Kakiuchi, Nichthida Tangnuntachai, Thamathorn Assanasen, Wimonmas Sitthi, Hamidah Muhamad, Panisinee Lawasut, Sunisa Kongkiatkamon, Udomsak Bunworasate, Koji Izutsu, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Seishi Ogawa, Kenichi Yoshida & Ponlapat Rojnuckarin
Pages: 95-103
Published online: 23 Sep 2020
AbstractforFrequent mutations in HLA and related genes in extranodal NK/T cell lymphomas | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 410 Views
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Article
A low lymphocyte-to-monocyte ratio is an independent predictor of poorer survival and higher risk of histological transformation in follicular lymphoma
Pablo Mozas, Andrea Rivero, Alfredo Rivas-Delgado, Ferran Nadeu, Guillem Clot, Juan Gonzalo Correa, Carlos Castillo, Alex Bataller, Tycho Baumann, Eva Giné, Julio Delgado, Neus Villamor, Elías Campo, Patricia Pérez-Galán, Laura Magnano & Armando López-Guillermo
Pages: 104-111
Published online: 19 Sep 2020
AbstractforA low lymphocyte-to-monocyte ratio is an independent predictor of poorer survival and higher risk of histological transformation in follicular lymphoma | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 401 Views
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Article
Excellent outcomes in older patients with primary CNS lymphoma treated with R-MPV/cytarabine without whole brain radiotherapy or autologous stem cell transplantation therapy
Maciej Tatarczuch, Erin Paul, Michael Gilberston, Gareth P. Gregory, Constantine Tam, Hang Quach, Ali Bazargan, Robin Filshie, Matthew Ku, Amanda Tey, Jake Shortt & Stephen Opat
Pages: 112-117
Published online: 27 Sep 2020
AbstractforExcellent outcomes in older patients with primary CNS lymphoma treated with R-MPV/cytarabine without whole brain radiotherapy or autologous stem cell transplantation therapy | Full Text | References | PDF (1.9 MB) | EPUB
  • 542 Views
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Article
Outcome of relapsed/refractory diffuse large B-cell lymphoma patients treated with polatuzumab vedotin-based therapy: real-life experience
Yafit Segman, Elena Ribakovsky, Abraham Avigdor, Yair Goldhecht, Vladimir Vainstein, Neta Goldschmidt, Shimrit Harlev, Netanel Horwitz, Odit Gutwein, Ronit Gurion, Gilad Itchaki, Uri Abadi, Anatoly Nemets, Orit Sofer, Miri Zektser, Tamar Tadmor, Nagib Dally, Kalman Filanovsky, Merav Leiba, Nadav Sarid, Noam Benyamini, Yair Herishanu, Ron Ram, Chava Perry & Irit Avivi
Pages: 118-124
Published online: 27 Sep 2020
AbstractforOutcome of relapsed/refractory diffuse large B-cell lymphoma patients treated with polatuzumab vedotin-based therapy: real-life experience | Full Text | References | PDF (920.4 KB) | EPUB | Supplemental
  • 1938 Views
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Article
Impact of response to treatment in health-related quality of life patient-reported outcomes in elderly patients with relapsed multiple myeloma
Albert Oriol, Gladys Ibarra, Eugènia Abella, Cristina Motlló, Maria-Teresa Cibeira, Antoni Garcia, Lourdes Escoda, Miquel Granell, Randa Ben-Azaiz, Marta Cervera, Elena Cabezudo, Carlos Fernandez, Laura Rosiñol & On behalf of the GEMMAC Study Group
Pages: 125-135
Published online: 15 Sep 2020
AbstractforImpact of response to treatment in health-related quality of life patient-reported outcomes in elderly patients with relapsed multiple myeloma | Full Text | References | PDF (2.5 MB) | EPUB
  • 328 Views
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Article
MiR-181a enhances drug sensitivity of mixed lineage leukemia-rearranged acute myeloid leukemia by increasing poly(ADP-ribose) polymerase1 acetylation
Di Zhou, Peipei Xu, Xuan Zhou, Zhenyu Diao, Jian Ouyang, Guijun Yan & Bing Chen
Pages: 136-146
Published online: 30 Sep 2020
AbstractforMiR-181a enhances drug sensitivity of mixed lineage leukemia-rearranged acute myeloid leukemia by increasing poly(ADP-ribose) polymerase1 acetylation | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 155 Views
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Article
A multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings?
Douglas R. A. Silveira, Juan L. Coelho-Silva, Wellington F. Silva, Grant Vallance, Diego A. Pereira-Martins, Maria I. A. Madeira, Lorena L. Figueredo-Pontes, Elvira D. R. P. Velloso, Belinda P. Simões, Andy Peniket, Robert Danby, Eduardo M. Rego, Paresh Vyas, Fabiola Traina, Israel Bendit, Lynn Quek & Vanderson Rocha
Pages: 147-157
Published online: 30 Sep 2020
AbstractforA multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings? | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 225 Views
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Article
Comparison of salvage chemotherapy regimens and prognostic significance of minimal residual disease in relapsed/refractory acute myeloid leukemia
Muhammad Umair Mushtaq, Alexandra M. Harrington, Sibgha Gull Chaudhary, Laura C. Michaelis, Karen-Sue B. Carlson, Sameem Abedin, Lyndsey Runass, Natalie S. Callander, Michael J. Fallon, Mark Juckett, Aric C. Hall, Peiman Hematti, Ryan J. Mattison, Ehab L. Atallah & Guru Subramanian Guru Murthy
Pages: 158-166
Published online: 19 Sep 2020
AbstractforComparison of salvage chemotherapy regimens and prognostic significance of minimal residual disease in relapsed/refractory acute myeloid leukemia | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 846 Views
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Article
The expression of MDM2, MDM4, p53 and p21 in myeloid neoplasms and the effect of MDM2/MDM4 dual inhibitor
Mohammad Eskandari, Yang Shi, John Liu, Joseph Albanese, Swati Goel, Amit Verma & Yanhua Wang
Pages: 167-175
Published online: 14 Sep 2020
AbstractforThe expression of MDM2, MDM4, p53 and p21 in myeloid neoplasms and the effect of MDM2/MDM4 dual inhibitor | Full Text | References | PDF (1.7 MB) | EPUB
  • 563 Views
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Article
Tolerability and toxicity of pegaspargase in adults 40 years and older with acute lymphoblastic leukemia
Ryan J. Daley, Sridevi Rajeeve, Charlene C. Kabel, Jeremy J. Pappacena, Sarah E. Stump, Jessica A. Lavery, Martin S. Tallman, Mark B. Geyer & Jae H. Park
Pages: 176-184
Published online: 26 Sep 2020
AbstractforTolerability and toxicity of pegaspargase in adults 40 years and older with acute lymphoblastic leukemia | Full Text | References | PDF (1.2 MB) | EPUB
  • 605 Views
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Article
High PRDM16 expression predicts poor outcomes in adult acute myeloid leukemia patients with intermediate cytogenetic risk: a comprehensive cohort study from a single Chinese center
Feng-Ting Dao, Wen-Min Chen, Ling-Yu Long, Ling-Di Li, Lu Yang, Jun Wang, Yan-Rong Liu, Hao Jiang, Xiao-Hui Zhang, Qian Jiang & Ya-Zhen Qin
Pages: 185-193
Published online: 09 Sep 2020
AbstractforHigh PRDM16 expression predicts poor outcomes in adult acute myeloid leukemia patients with intermediate cytogenetic risk: a comprehensive cohort study from a single Chinese center | Full Text | References | PDF (1.2 MB) | EPUB
  • 238 Views
  • 3 CrossRef citations
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Article
Dasatinib treatment long-term results among imatinib-resistant/intolerant patients with chronic phase chronic myeloid leukemia are favorable in daily clinical practice
Daniela Zackova, Hana Klamova, Petra Belohlavkova, Lukas Stejskal, Tereza Necasova, Lukas Semerad, Barbora Weinbergerova, Dana Srbova, Jaroslava Voglova, Petra Cicatkova, Zuzana Sustkova, Tomas Hornak, Jana Baranova, Jirina Prochazkova & Jiri Mayer
Pages: 194-202
Published online: 06 Oct 2020
AbstractforDasatinib treatment long-term results among imatinib-resistant/intolerant patients with chronic phase chronic myeloid leukemia are favorable in daily clinical practice | Full Text | References | PDF (860.5 KB) | EPUB | Supplemental
  • 391 Views
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Article
The prognostic implications of tetraploidy/near-Tetraploidy in acute myeloid leukemia: a case series and systematic review of the literature
John Xie, Adeem Nachabe, Lindsey J. Hathaway, Bachir Farah, Bachir Berbari, Yuwen Li, Theresa C. Brown, Janet L. Schmid, Francisco Socola, Nakhle S. Saba & Hana Safah
Pages: 203-210
Published online: 29 Sep 2020
AbstractforThe prognostic implications of tetraploidy/near-Tetraploidy in acute myeloid leukemia: a case series and systematic review of the literature | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 573 Views
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Article
Highly increased risk of fracture in patients with myeloproliferative neoplasm
Peter Johansson, Hallgerdur Lind Kristjansdottir, Helena Johansson, Ana Jakir, Dan Mellström & Cataharina Lewerin
Pages: 211-217
Published online: 10 Sep 2020
AbstractforHighly increased risk of fracture in patients with myeloproliferative neoplasm | Full Text | References | PDF (599.2 KB) | EPUB
  • 240 Views
  • 1 CrossRef citations
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Article
Increased myeloid-derived suppressor cells in patients with myelodysplastic syndromes suppress CD8+ T lymphocyte function through the STAT3-ARG1 pathway
Xiao Qi, Huijuan Jiang, Pei Liu, Ning Xie, Rong Fu, Huaquan Wang, Chunyan Liu, Tian Zhang, Huaqing Wang & Zonghong Shao
Pages: 218-223
Published online: 26 Sep 2020
AbstractforIncreased myeloid-derived suppressor cells in patients with myelodysplastic syndromes suppress CD8+ T lymphocyte function through the STAT3-ARG1 pathway | Full Text | References | PDF (1.2 MB) | EPUB
  • 301 Views
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Article
Translocation t(1;19)(q23;p13) in adult acute lymphoblastic leukemia – a distinct subtype with favorable prognosis
Musa Yilmaz, Hagop M. Kantarjian, Gokce Toruner, C. Cameron Yin, Rashmi Kanagal-Shamanna, Jorge E. Cortes, Ghayyas Issa, Nicholas J. Short, Joseph D. Khoury, Guillermo Garcia-Manero, Farhad Ravandi, Tapan Kadia, Marina Konopleva, William G. Wierda, Nitin Jain, Zeev Estrov, Koji Sasaki, Sherry Pierce, Susan M. O'Brien & Elias J. Jabbour
Pages: 224-228
Published online: 21 Sep 2020
AbstractforTranslocation t(1;19)(q23;p13) in adult acute lymphoblastic leukemia – a distinct subtype with favorable prognosis | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 548 Views
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Letters to the Editor

Letter
Prognostic impact of serum CXC chemokine ligands 4 and 7 on myelodysplastic syndromes post allogeneic hematopoietic cell transplant
Binod Dhakal, Tao Wang, Michelle Kuxhausen, Fenlu Zhu, Carolyn Taylor, Stephen R. Spellman, Michael R. Verneris, Katharine Hsu, Katharina Fleischhauer, Stephanie J. Lee, Yung-Tsi Bolon, Karen-Sue Carlson, Aziz Nazha & Wael Saber
Pages: 229-233
Published online: 13 Sep 2020
First Page PreviewforPrognostic impact of serum CXC chemokine ligands 4 and 7 on myelodysplastic syndromes post allogeneic hematopoietic cell transplant | Full Text | References | PDF (544.1 KB) | EPUB | Supplemental
  • 139 Views
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Letter
Comparison of outpatient care following intensive induction versus post-remission chemotherapy for adults with acute myeloid leukemia and other high-grade myeloid neoplasms
Anna B. Halpern, Megan Othus, Nicholas P. Howard, Paul C. Hendrie, Mary-Elizabeth M. Percival, Bart L. Scott, Terry B. Gernsheimer, Nikita V. Baclig, Sarah A. Buckley, Ryan D. Cassaday, Garrett A. Hartley, Verna L. Welch, Elihu H. Estey & Roland B. Walter
Pages: 234-238
Published online: 13 Sep 2020
First Page PreviewforComparison of outpatient care following intensive induction versus post-remission chemotherapy for adults with acute myeloid leukemia and other high-grade myeloid neoplasms | Full Text | References | PDF (691 KB) | EPUB | Supplemental
  • 188 Views
  • 3 CrossRef citations
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Letter
PECAM is an effective and safe anthracycline-containing third-line regimen for patients with relapsed or refractory non-Hodgkin lymphoma
Fumi Nakamura, Honoka Arai, Katsuya Tokita, Shiho Furuichi, Fusako Sugita-Nagasawa, Wataru Takahashi, Tomoyuki Handa, Hisako Iso, Jiro Tadokoro, Shigeharu Tsurumi, Yuko Nakamura, Yuka Nakamura, Ko Sasaki, Sachiko Seo, Motoshi Ichikawa & Kinuko Mitani
Pages: 239-242
Published online: 11 Sep 2020
First Page PreviewforPECAM is an effective and safe anthracycline-containing third-line regimen for patients with relapsed or refractory non-Hodgkin lymphoma | Full Text | References | PDF (530.1 KB) | EPUB
  • 143 Views
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Letter
Lymphoma-like double-hit genetic abnormalities (MYC/IGH and IGH/BCL2) in a case of non-secretory multiple myeloma
Erin A. Kaya, Linda B. Baughn, Truc Pham, Rhett P. Ketterling, Shaji K. Kumar & Dragan Jevremovic
Pages: 243-246
Published online: 21 Sep 2020
First Page PreviewforLymphoma-like double-hit genetic abnormalities (MYC/IGH and IGH/BCL2) in a case of non-secretory multiple myeloma | Full Text | References | PDF (1.8 MB) | EPUB
  • 1439 Views
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Open Access
Effect of antibiotic use on outcomes in patients with Hodgkin lymphoma treated with immune checkpoint inhibitors
Steven R. Hwang, Alexandra Higgins, Natalia E. Castillo Almeida, Betsy LaPlant, Matthew J. Maurer, Stephen M. Ansell, Thomas E. Witzig, Gita Thanarajasingam & N. Nora Bennani
Pages: 247-251
Published online: 06 Oct 2020
First Page PreviewforEffect of antibiotic use on outcomes in patients with Hodgkin lymphoma treated with immune checkpoint inhibitors | Full Text | References | PDF (1.4 MB) | EPUB
  • 358 Views
  • 7 CrossRef citations
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Letter
Does early chimerism testing predict outcomes after allogeneic hematopoietic stem cell transplantation?
Luke Mountjoy, Jeanne Palmer, Katie L. Kunze, Nandita Khera, Lisa Z. Sproat, Jose F. Leis, Pierre Noel, James L. Slack & Tania Jain
Pages: 252-254
Published online: 04 Oct 2020
First Page PreviewforDoes early chimerism testing predict outcomes after allogeneic hematopoietic stem cell transplantation? | Full Text | References | PDF (304.6 KB) | EPUB | Supplemental
  • 3270 Views
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Open Access

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