Leukemia & Lymphoma, Volume 62, Issue 11 (2021)

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Leukemia & Lymphoma, Volume 62, Issue 11 (2021)

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Commentary

Article Commentary
Should high risk smoldering myeloma be treated outside a clinical trial: NO
Morie A Gertz & Iuliana Vaxman
Pages: 2565-2567
Published online: 14 Jul 2021
First Page PreviewforShould high risk smoldering myeloma be treated outside a clinical trial: NO | Full Text | References | PDF (450.6 KB) | EPUB | Supplemental
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Review

Review
Targeting CD123 in hematologic malignancies: identifying suitable patients for targeted therapy
Mrinal M. Patnaik, Tariq I. Mughal, Christopher Brooks, Ross Lindsay & Naveen Pemmaraju
Pages: 2568-2586
Published online: 17 May 2021
AbstractforTargeting CD123 in hematologic malignancies: identifying suitable patients for targeted therapy | Full Text | References | PDF (2.4 MB) | EPUB
  • 5477 Views
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Open Access
Review
CAR-T cell persistence in the treatment of leukemia and lymphoma
Arjun Gupta & Saar Gill
Pages: 2587-2599
Published online: 19 Apr 2021
AbstractforCAR-T cell persistence in the treatment of leukemia and lymphoma | Full Text | References | PDF (1.4 MB) | EPUB
  • 1304 Views
  • 8 CrossRef citations
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Review
Toci or not toci: innovations in the diagnosis, prevention, and early management of cytokine release syndrome
Rahul Banerjee, Bita Fakhri & Nina Shah
Pages: 2600-2611
Published online: 21 Jun 2021
AbstractforToci or not toci: innovations in the diagnosis, prevention, and early management of cytokine release syndrome | Full Text | References | PDF (978 KB) | EPUB
  • 790 Views
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Original Articles

Article
Rationale for once-daily or twice-daily dosing of zanubrutinib in patients with mantle cell lymphoma
Ying C. Ou, Zhiyu Tang, William Novotny, Aileen Cohen, Kun Wang, Lucy Liu, Yuying Gao & Srikumar Sahasranaman
Pages: 2612-2624
Published online: 23 Jun 2021
AbstractforRationale for once-daily or twice-daily dosing of zanubrutinib in patients with mantle cell lymphoma | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 5518 Views
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Open Access
Article
A phase 1/2 study of the combination of acalabrutinib and vistusertib in patients with relapsed/refractory B-cell malignancies
Graham P. Collins, Tracy N. Clevenger, Kathleen A. Burke, Buyue Yang, Alex MacDonald, David Cunningham, Christopher P. Fox, Andre Goy, John Gribben, Grzegorz S. Nowakowski, Mark Roschewski, Julie M. Vose, Anusha Vallurupalli, Jean Cheung, Amelia Raymond, Barrett Nuttall, Dan Stetson, Brian A. Dougherty, Stein Schalkwijk, Larissa S. Carnevalli, Brandon Willis, Lin Tao, Elizabeth A. Harrington, Ahmed Hamdy, Raquel Izumi, J. Elizabeth Pease, Melanie M. Frigault & Ian Flinn
Pages: 2625-2636
Published online: 16 Jul 2021
AbstractforA phase 1/2 study of the combination of acalabrutinib and vistusertib in patients with relapsed/refractory B-cell malignancies | Full Text | References | PDF (2 MB) | EPUB
  • 2379 Views
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Open Access
Article
Targeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets
Joana M. Rodrigues, Anna Porwit, May Hassan, Sara Ek & Mats Jerkeman
Pages: 2637-2647
Published online: 03 Jun 2021
AbstractforTargeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 1932 Views
  • 1 CrossRef citations
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Open Access
Article
Hsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma
Qi Chen, Shenglin Liu, Kaoyuan Zhang, Bo Yu, Wei Zhang, Hongyu Zhang & Xiaofan Chen
Pages: 2648-2656
Published online: 03 Jun 2021
AbstractforHsa-miR-372-5p regulates the NIMA related kinase 7 and IL-1β release in NK/T-cell lymphoma | Full Text | References | PDF (1.5 MB) | EPUB
  • 168 Views
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Article
Treatment and outcome patterns of patients with Waldenström’s macroglobulinemia: a large, multicenter retrospective review in China
Xin-xin Cao, Shu-hua Yi, Zhong-xing Jiang, Jing-song He, Wei Yang, Juan Du, Chun-yan Sun, Yu Wu, Wen-ming Chen, Xiao-jun Liu, Bing-zong Li, Chun-rui Li, Wei Sang, Qin-hua Liu, Xiao-xia Chu, Fei Li, Ou Bai, Min Mao, Rong Fu, Wei Wang, Li-hong Liu, Lu-qun Wang, Yu-jun Dong, Jun Luo, Zhen-ling Li, Yong-qiang Wei, Qi-ke Zhang, Jing Liu, Kai-yang Ding, Liang Zou, Bi-yun Chen, Luo-ming Hua, Hong-mei Jing, Juan He, Liang Wang, Jian Li & Lu-gui Qiu
Pages: 2657-2664
Published online: 09 Jun 2021
AbstractforTreatment and outcome patterns of patients with Waldenström’s macroglobulinemia: a large, multicenter retrospective review in China | Full Text | References | PDF (1.5 MB) | EPUB
  • 470 Views
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Article
Waldenström macroglobulinemia and relationship to immune deficiency
Anthony Levy, Stéphanie Guidez, Céline Debiais, Isabelle Princet, Sabrina Bouyer, Elodie Dindinaud, Vincent Delwail, Thomas Systchenko, Niels Moya, Cécile Gruchet, Florence Sabirou, Arthur Bobin, Hélène Gardeney, Laly Nsiala, Laura Cailly, Gaëlle Olivier, Carine Motard, Emmanuel Fleck, Anne Corby, Christophe Roul, Guillaume Denis, Céline Dieval, Xavier Leleu & Cécile Tomowiak
Pages: 2665-2670
Published online: 04 Jun 2021
AbstractforWaldenström macroglobulinemia and relationship to immune deficiency | Full Text | References | PDF (886.1 KB) | EPUB
  • 187 Views
  • 1 CrossRef citations
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Article
Body mass index and survival of patients with lymphoma
Dai Chihara, Melissa C. Larson, Dennis P. Robinson, Carrie A. Thompson, Matthew J. Maurer, Carla Casulo, Priyanka Pophali, Brian K. Link, Thomas M. Habermann, Andrew L. Feldman, Christopher R. Flowers, James R. Cerhan & Lindsay M. Morton
Pages: 2671-2678
Published online: 14 Jun 2021
AbstractforBody mass index and survival of patients with lymphoma | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 633 Views
  • 3 CrossRef citations
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Article
Immune modulatory effects of Idelalisib in stromal cells of chronic lymphocytic leukemia
Sarah Handl, Franziska von Heydebrand, Simon Voelkl, Robert A. J. Oostendorp, Jochen Wilke, Anita N. Kremer, Andreas Mackensen & Gloria Lutzny-Geier
Pages: 2679-2689
Published online: 17 May 2021
AbstractforImmune modulatory effects of Idelalisib in stromal cells of chronic lymphocytic leukemia | Full Text | References | PDF (2 MB) | EPUB
  • 1708 Views
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Open Access
Article
Pan-PI3Ki targets multiple B-ALL microenvironment interactions that fuel systemic and CNS relapse
Sarah M. Ridge, Andrew E. Whiteley, Hisayuki Yao, Trevor T. Price, Maegan L. Brockman, Andrew S. Murray, Brennan G. Simon, Prioty Islam & Dorothy A. Sipkins
Pages: 2690-2702
Published online: 06 Aug 2021
AbstractforPan-PI3Ki targets multiple B-ALL microenvironment interactions that fuel systemic and CNS relapse | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
  • 366 Views
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Article
Variables associated with patient-reported outcomes in patients with myeloproliferative neoplasms
Dayu Shi, Hongxia Shi, Xiaoli Liu, Minghui Duan, Junling Zhuang, Xin Du, Ling Qin, Wuhan Hui, Rong Liang, Meifang Wang, Ye Chen, Dongyun Li, Wei Yang, Gusheng Tang, Weihua Zhang, Xia Kuang, Wei Su, Yanqiu Han, Limei Chen, Jihong Xu, Zhuogang Liu, Jian Huang, Chunting Zhao, Hongyan Tong, Jianda Hu, Chunyan Chen, Xiequn Chen, Zhijian Xiao & Qian Jiang
Pages: 2703-2715
Published online: 08 Jun 2021
AbstractforVariables associated with patient-reported outcomes in patients with myeloproliferative neoplasms | Full Text | References | PDF (1.7 MB) | EPUB
  • 440 Views
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Article
Quantitative analyses of CD7, CD33, CD34, CD56, and CD123 within the FLT3-ITD/NPM1-MUT myeloblastic/monocytic bulk AML blastic populations
Dan-Sebastian Soare, Eugen Radu, Ion Dumitru, Ana Maria Vlădăreanu & Horia Bumbea
Pages: 2716-2726
Published online: 26 May 2021
AbstractforQuantitative analyses of CD7, CD33, CD34, CD56, and CD123 within the FLT3-ITD/NPM1-MUT myeloblastic/monocytic bulk AML blastic populations | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 368 Views
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Article
Evolving patterns of care and outcomes in relapsed/refractory FLT3 mutated acute myeloid leukemia adult patients
Blanca Boluda, David Martínez-Cuadrón, Lorenzo Algarra, Isabel Cano, María J. Sayas, Evelyn Acuña-Cruz, Albert Blanco, Javier Marco-Ayala, Rosalía DeLapuerta, Álvaro Díaz-González, Mar Tormo, Rebeca Rodríguez-Veiga, Raimundo García, José L. Piñana, María López-Pavía, Eva Barragán, María L. Amigo, Claudia Sargas, Aurelio López, Antonio Solana-Altabella, Cristina Gil, Juan Eduardo Megías-Vericat, Miguel A. Sanz & Pau Montesinos
Pages: 2727-2736
Published online: 14 Jun 2021
AbstractforEvolving patterns of care and outcomes in relapsed/refractory FLT3 mutated acute myeloid leukemia adult patients | Full Text | References | PDF (2.5 MB) | EPUB
  • 424 Views
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Article
Combined impact of HLA-allele matching and the CD34-positive cell dose on optimal unit selection for single-unit cord blood transplantation in adults
Toshio Yabe, Masahiro Satake, Takeshi Odajima, Naoko Watanabe-Okochi, Fumihiro Azuma, Koichi Kashiwase, Kayoko Matsumoto, Takeshi Orihara, Hiromasa Yabe, Shunichi Kato, Koji Kato, Shunro Kai, Tetsuo Mori, Satoko Morishima, Minoko Takanashi, Kazunori Nakajima, Makoto Murata, Yasuo Morishima & on behalf of Japanese Cord Blood Transplantation Histocompatibility Research Group
Pages: 2737-2746
Published online: 15 Jun 2021
AbstractforCombined impact of HLA-allele matching and the CD34-positive cell dose on optimal unit selection for single-unit cord blood transplantation in adults | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 187 Views
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Article
Eltrombopag for enhancement of platelet engraftment in patients undergoing allogeneic cord blood transplantation
Oren Pasvolsky, Liat Shargian, Uri Rozovski, Ofir Wolach, Ron Ram, Michael Y. Shapira, Batia Avni, Polina Stepensky, Moshe Israeli, Liat Vidal-Fisher, Ofer Shpilberg, Pia Raanani & Moshe Yeshurun
Pages: 2747-2754
Published online: 20 May 2021
AbstractforEltrombopag for enhancement of platelet engraftment in patients undergoing allogeneic cord blood transplantation | Full Text | References | PDF (1 MB) | EPUB
  • 263 Views
  • 3 CrossRef citations
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Article
Mean platelet volume is a predictive and prognostic marker for patients with acute myeloid leukemia: a two-center retrospective analysis
Mesut Tığlıoğlu, Murat Albayrak, Servihan Doğan, Fatma Yılmaz, Pınar Akyol, Buğra Sağlam, Merih Reis Aras, Abdulkerim Yıldız, Hacer Berna Afacan Öztürk & İmdat Dilek
Pages: 2755-2761
Published online: 20 May 2021
AbstractforMean platelet volume is a predictive and prognostic marker for patients with acute myeloid leukemia: a two-center retrospective analysis | Full Text | References | PDF (851.4 KB) | EPUB
  • 206 Views
  • 2 CrossRef citations
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Article
What is the optimal time to initiate hypomethylating agents (HMAs) in higher risk myelodysplastic syndromes (MDSs)?
Rami Komrokji, Najla Al Ali, Eric Padron, Jeffrey Lancet, Aziz Nazha, David Steensma, Amy DeZern, Gail Roboz, Guillermo Garcia-Manero, Mikkael A. Sekeres & David Sallman
Pages: 2762-2767
Published online: 11 Jun 2021
AbstractforWhat is the optimal time to initiate hypomethylating agents (HMAs) in higher risk myelodysplastic syndromes (MDSs)? | Full Text | References | PDF (811.5 KB) | EPUB
  • 194 Views
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Article
microRNAs as the biomarkers of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma
Karolina Łuczkowska, Dorota Rogińska, Zofia Ulańczyk, Krzysztof Safranow, Edyta Paczkowska, Bartłomiej Baumert, Sławomir Milczarek, Bogumiła Osękowska, Martyna Górska, Ewa Borowiecka, Krzysztof Sommerfeld, Piotr Zawodny, Aneta Szudy-Szczyrek, Marek Hus & Bogusław Machaliński
Pages: 2768-2776
Published online: 07 Jun 2021
AbstractformicroRNAs as the biomarkers of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma | Full Text | References | PDF (907 KB) | EPUB | Supplemental
  • 1919 Views
  • 3 CrossRef citations
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Open Access
Article
Cost-effectiveness of once-weekly selinexor, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma
Kishan K. Patel, Terri Parker, Mengyang Di, Noffar Bar, Scott F. Huntington & Smith Giri
Pages: 2777-2784
Published online: 21 Jun 2021
AbstractforCost-effectiveness of once-weekly selinexor, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 333 Views
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Article
Diabetes, but not pre-diabetes, is associated with shorter time to second-line therapy and worse outcomes in patients with multiple myeloma
Irit Avivi, Naama Yekutiel, Inbar Cohen, Yael C. Cohen, Gabriel Chodick & Clara Weil
Pages: 2785-2792
Published online: 08 Jun 2021
AbstractforDiabetes, but not pre-diabetes, is associated with shorter time to second-line therapy and worse outcomes in patients with multiple myeloma | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 117 Views
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Letters to the Editor

Letter
The landscape of trials for smoldering multiple myeloma: endpoints, trial design, and lessons learnt
Ghulam Rehman Mohyuddin, Evguenia Ouchveridze, Aaron Goodman & Vinay Prasad
Pages: 2793-2795
Published online: 11 Jun 2021
First Page PreviewforThe landscape of trials for smoldering multiple myeloma: endpoints, trial design, and lessons learnt | Full Text | References | PDF (347.8 KB) | EPUB
  • 308 Views
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Letter
Primary thyroid lymphoma: survival analysis of SEER database (1995–2016)
Jorge A. Florindez, Juan Pablo Alderuccio, Isildinha M. Reis & Izidore S. Lossos
Pages: 2796-2799
Published online: 27 May 2021
First Page PreviewforPrimary thyroid lymphoma: survival analysis of SEER database (1995–2016) | Full Text | References | PDF (766.9 KB) | EPUB
  • 295 Views
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Letter
Reliable IGHV status assessment by next generation sequencing in routine practice for chronic lymphocytic leukemia
Marie-Laure Boulland, Samuel Vic, Florian Thonier, Michel Ganard, Thierry Lamy, Thierry Fest, Sophie de Guibert & Cédric Pastoret
Pages: 2800-2803
Published online: 01 Jun 2021
First Page PreviewforReliable IGHV status assessment by next generation sequencing in routine practice for chronic lymphocytic leukemia | Full Text | References | PDF (623.4 KB) | EPUB
  • 385 Views
  • 1 CrossRef citations
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Letter
Comorbidities and socioeconomic status are predictors of survival in children and young adults with Burkitt lymphoma
Elysia Alvarez, Thuy Le, Justine Kahn, Lena Winestone, Qian Li & Theresa Keegan
Pages: 2804-2807
Published online: 01 Jun 2021
First Page PreviewforComorbidities and socioeconomic status are predictors of survival in children and young adults with Burkitt lymphoma | Full Text | References | PDF (683.6 KB) | EPUB
  • 188 Views
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Letter
Mutations known from B-cell lymphoid malignancies are not found in CD34+ stem cells from patients with lymphoma
Simon Husby, Francesco Favero, Francisco G. Rodriguez-Gonzalez, Lesley A. Sutton, Eva K. Haastrup, Andreas Due Ørskov, Jakob W. Hansen, Bente Arboe, Derya Aslan, Erik Clasen-Linde, Lise Mette Rahbek Gjerdrum, Jette Sønderskov Gørlev, Peter Brown, Anne Fischer-Nielsen, Richard Rosenquist, Joachim Weischenfeldt & Kirsten Grønbæk
Pages: 2808-2811
Published online: 21 Jun 2021
First Page PreviewforMutations known from B-cell lymphoid malignancies are not found in CD34+ stem cells from patients with lymphoma | Full Text | References | PDF (539.6 KB) | EPUB | Supplemental
  • 202 Views
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Letter
Moxetumomab pasudotox as re-treatment for heavily-pretreated relapsed hairy cell leukemia
Ilana R. Yurkiewicz, Steve Coutre, Herve Ghesquieres, Ira Pastan & Robert J. Kreitman
Pages: 2812-2814
Published online: 25 May 2021
First Page PreviewforMoxetumomab pasudotox as re-treatment for heavily-pretreated relapsed hairy cell leukemia | Full Text | References | PDF (405.2 KB) | EPUB
  • 161 Views
  • 6 CrossRef citations
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