Leukemia & Lymphoma, Volume 62, Issue 4 (2021)

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Leukemia & Lymphoma, Volume 62, Issue 4 (2021)

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Commentary

Article Commentary
The importance of immunoparesis in multiple myeloma
Morie A. Gertz
Pages: 769-770
Published online: 25 Dec 2020
CitationforThe importance of immunoparesis in multiple myeloma | Full Text | References | PDF (349.3 KB) | EPUB
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Reviews

Chronic lymphoproliferative disorders and secondary cancers in the era of purine analogues and beyond
Sean Harrop, Aaron Polliack & Constantine S. Tam
Pages: 771-778
Published online: 22 Nov 2020
AbstractforChronic lymphoproliferative disorders and secondary cancers in the era of purine analogues and beyond | Full Text | References | PDF (742.9 KB) | EPUB
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Incorporation of Novel therapies for the treatment of acute myeloid leukemia: a perspective
Julian A. Waksal & Martin S. Tallman
Pages: 779-790
Published online: 04 Feb 2021
AbstractforIncorporation of Novel therapies for the treatment of acute myeloid leukemia: a perspective | Full Text | References | PDF (874.7 KB) | EPUB
  • 295 Views
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Original Articles

Article
Phase 2, multicenter GIBB study of obinutuzumab plus bendamustine in previously untreated patients with chronic lymphocytic leukemia
Jeff P. Sharman, John M. Burke, Habte A. Yimer, Michael A. Boxer, Sunil Babu, Jia Li, Yong Mun, Alexey V. Danilov & on behalf of the GIBB study investigators
Pages: 791-800
Published online: 26 Nov 2020
AbstractforPhase 2, multicenter GIBB study of obinutuzumab plus bendamustine in previously untreated patients with chronic lymphocytic leukemia | Full Text | References | PDF (934.6 KB) | EPUB
  • 1885 Views
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Open Access
Article
Clinical relevance of NKT cells and soluble MIC-A in Hodgkin lymphoma
Jorge Vela-Ojeda, Flor Del Carmen Perez-Retiguin, Ana Cristina Olivas-Bejarano, Miriam America Garcia-Ruiz Esparza, Jaime Garcia-Chavez, Abraham Majluf-Cruz, Elba Reyes-Maldonado & Laura Arcelia Montiel-Cervantes
Pages: 801-809
Published online: 07 Dec 2020
AbstractforClinical relevance of NKT cells and soluble MIC-A in Hodgkin lymphoma | Full Text | References | PDF (995 KB) | EPUB | Supplemental
  • 194 Views
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Article
Safety and efficacy of navitoclax, a BCL-2 and BCL-XL inhibitor, in patients with relapsed or refractory lymphoid malignancies: results from a phase 2a study
Sven de Vos, John P. Leonard, Jonathan W. Friedberg, Jasmine Zain, Kieron Dunleavy, Rod Humerickhouse, John Hayslip, John Pesko & Wyndham H. Wilson
Pages: 810-818
Published online: 25 Nov 2020
AbstractforSafety and efficacy of navitoclax, a BCL-2 and BCL-XL inhibitor, in patients with relapsed or refractory lymphoid malignancies: results from a phase 2a study | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 4384 Views
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Open Access
Article
Comparison of prognostic scores in transplant-ineligible patients with peripheral T-cell lymphoma not otherwise specified and angioimmunoblastic T-cell lymphoma: a retrospective study from the national hospital organization in Japan
Satoshi Yamasaki, Hiroatsu Iida, Isao Yoshida, Takuya Komeno, Morio Sawamura, Morio Matsumoto, Naoshiro Sekiguchi, Terutoshi Hishita, Kazutaka Sunami, Takeshi Shimomura, Hiroshi Takatsuki, Shinichiro Yoshida, Maki Otsuka, Takeharu Kato, Yoshiaki Kuroda, Tadashi Ooyama, Yasuhiro Suzuki, Koichi Ohshima, Hirokazu Nagai & Hiromi Iwasaki
Pages: 819-827
Published online: 09 Nov 2020
AbstractforComparison of prognostic scores in transplant-ineligible patients with peripheral T-cell lymphoma not otherwise specified and angioimmunoblastic T-cell lymphoma: a retrospective study from the national hospital organization in Japan | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 167 Views
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Article
Relapsed/refractory diffuse large B-cell lymphoma patients. A multicenter retrospective analysis of eligibility criteria for car-T cell therapy
Alice Di Rocco, Antonio Cuneo, Arianna Di Rocco, Francesco Merli, Giulia De Luca, Luigi Petrucci, Michela Ansuinelli, Domenico Penna, Francesco Rotondo, Gian Matteo Rigolin, Mariateresa Giaimo, Francesca Re, Alessio Farcomeni, Maurizio Martelli & Robin Foà
Pages: 828-836
Published online: 04 Dec 2020
AbstractforRelapsed/refractory diffuse large B-cell lymphoma patients. A multicenter retrospective analysis of eligibility criteria for car-T cell therapy | Full Text | References | PDF (1.2 MB) | EPUB
  • 687 Views
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Article
No increased bleeding events in patients with relapsed chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma treated with idelalisib
Jacqueline C. Barrientos, Peter Hillmen, Gilles Salles, Jeff Sharman, Stephan Stilgenbauer, Oksana Gurtovaya, Guan Xing, Bianca Ruzicka, Pankaj Bhargava, Paolo Ghia & John M. Pagel
Pages: 837-845
Published online: 10 Dec 2020
AbstractforNo increased bleeding events in patients with relapsed chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma treated with idelalisib | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1679 Views
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Open Access
Article
Life-threatening complications after high-dose methotrexate and the benefits of glucarpidase as salvage therapy: a cohort study of 468 patients
Chloé Medrano, Lucie Oberic, Florent Puisset, Christian Recher, Delphine Larrieu-Ciron, Loïc Ysebaert, Caroline Protin, Muriel Picard, Sophie Perriat, Etienne Chatelut, Sarah Bertoli, Françoise Huguet, Suzanne Tavitian & Stanislas Faguer
Pages: 846-853
Published online: 12 Nov 2020
AbstractforLife-threatening complications after high-dose methotrexate and the benefits of glucarpidase as salvage therapy: a cohort study of 468 patients | Full Text | References | PDF (854.7 KB) | EPUB | Supplemental
  • 409 Views
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Article
The DEP regimen is superior to the HLH-1994 regimen as first-line therapy for lymphoma-associated haemophagocytic lymphohistiocytosis
Guangqiang Meng, Yini Wang, Jingshi Wang & Zhao Wang
Pages: 854-860
Published online: 21 Nov 2020
AbstractforThe DEP regimen is superior to the HLH-1994 regimen as first-line therapy for lymphoma-associated haemophagocytic lymphohistiocytosis | Full Text | References | PDF (554.5 KB) | EPUB
  • 247 Views
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Article
CD31/PECAM-1 impacts engraftment, growth and spread of mantle cell lymphoma cells and positively correlates with extramedullary involvement
Petra Vockova, Jan Molinsky, Magdalena Klanova, Josef Karban, Martin Spacek, Ondrej Havranek, Kristyna Kupcova, Dmitry Kazantsev, Marek Trneny & Pavel Klener
Pages: 861-867
Published online: 25 Nov 2020
AbstractforCD31/PECAM-1 impacts engraftment, growth and spread of mantle cell lymphoma cells and positively correlates with extramedullary involvement | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 2023 Views
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Open Access
Article
Clinical application of next generation sequencing in lymphoma
Anthony J. Scott, Molly C. Tokaz, Maryann Shango, Sumana Devata, Shannon A. Carty, Mark S. Kaminski, Arul M. Chinnaiyan, Tycel J. Phillips & Ryan A. Wilcox
Pages: 868-873
Published online: 16 Nov 2020
AbstractforClinical application of next generation sequencing in lymphoma | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 415 Views
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Article
Posttreatment dFLC less than 10 mg/L predicts superior organ response and longer time to next treatment in newly diagnosed light-chain amyloidosis patients treated with bortezomib
Kai-ni Shen, Hui-lei Miao, Cong-li Zhang, Jun Feng, Lu Zhang, Xin-xin Cao, Dao-bin Zhou, Su Wei & Jian Li
Pages: 874-882
Published online: 20 Nov 2020
AbstractforPosttreatment dFLC less than 10 mg/L predicts superior organ response and longer time to next treatment in newly diagnosed light-chain amyloidosis patients treated with bortezomib | Full Text | References | PDF (1.7 MB) | EPUB
  • 198 Views
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Article
Deep and partial immunoparesis is a poor prognostic factor for newly diagnosed multiple myeloma patients
Chuanying Geng, Guangzhong Yang, Huijuan Wang, Yin Wu, Yun Leng, Huixing Zhou, Zhiyao Zhang, Yuan Jian & Wenming Chen
Pages: 883-890
Published online: 04 Dec 2020
AbstractforDeep and partial immunoparesis is a poor prognostic factor for newly diagnosed multiple myeloma patients | Full Text | References | PDF (1 MB) | EPUB
  • 259 Views
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Article
Interdisciplinary approach to multiple myeloma – time to diagnosis and warning signs
Georg W. Herget, Felix Kälberer, Gabriele Ihorst, Giulia Graziani, Lukas Klein, Michael Rassner, Christian Gehler, Johannes Jung, Hagen Schmal, Ralph Wäsch & Monika Engelhardt
Pages: 891-898
Published online: 21 Nov 2020
AbstractforInterdisciplinary approach to multiple myeloma – time to diagnosis and warning signs | Full Text | References | PDF (728.4 KB) | EPUB | Supplemental
  • 616 Views
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Article
Quantifying the difference in risk of adverse events by induction treatment regimen in pediatric acute lymphoblastic leukemia
Zachary E. West, Sharon M. Castellino, Caitlin Monroe, Amanda S. Thomas, Courtney McCracken & Tamara P. Miller
Pages: 899-908
Published online: 01 Dec 2020
AbstractforQuantifying the difference in risk of adverse events by induction treatment regimen in pediatric acute lymphoblastic leukemia | Full Text | References | PDF (1.3 MB) | EPUB
  • 219 Views
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Article
Management of chronic myeloid leukemia during pregnancy among patients treated with a tyrosine kinase inhibitor: a single-Center experience
Rita Assi, Hagop Kantarjian, Michael Keating, Naveen Pemmaraju, Srdan Verstovsek, Guillermo Garcia-Manero, Farhad Ravandi, Gautam Borthakur, Jenny Dahl, Elias Jabbour & Jorge E. Cortes
Pages: 909-917
Published online: 07 Dec 2020
AbstractforManagement of chronic myeloid leukemia during pregnancy among patients treated with a tyrosine kinase inhibitor: a single-Center experience | Full Text | References | PDF (1.4 MB) | EPUB
  • 587 Views
  • 8 CrossRef citations
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Article
Analysis of predictors of response to ruxolitinib in patients with myelofibrosis in the phase 3b expanded-access JUMP study
Vikas Gupta, Martin Griesshammer, Bruno Martino, Lynda Foltz, Renato Tavares, Haifa Kathrin Al-Ali, Pilar Giraldo, Paola Guglielmelli, Elza Lomaia, Catherine Bouard, Carole Paley, Ranjan Tiwari, Evren Zor & Pia Raanani
Pages: 918-926
Published online: 19 Nov 2020
AbstractforAnalysis of predictors of response to ruxolitinib in patients with myelofibrosis in the phase 3b expanded-access JUMP study | Full Text | References | PDF (1.6 MB) | EPUB
  • 5245 Views
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Open Access
Article
Investigating the gut microbial community and genes in children with differing levels of change in serum asparaginase activity during pegaspargase treatment for acute lymphoblastic leukemia
Katherine A. Dunn, Jessica Connors, Joseph P. Bielawski, Jacob T. Nearing, Morgan G. I. Langille, Johan Van Limbergen, Conrad V. Fernandez, Tamara MacDonald & Ketan Kulkarni
Pages: 927-936
Published online: 01 Dec 2020
AbstractforInvestigating the gut microbial community and genes in children with differing levels of change in serum asparaginase activity during pegaspargase treatment for acute lymphoblastic leukemia | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 317 Views
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Article
AML1-ETO inhibits acute myeloid leukemia immune escape by CD48
Zhiding Wang, Wei Guan, Mengzhen Wang, Jinghong Chen, Linlin Zhang, Yang Xiao, Lixin Wang, Yonghui Li & Li Yu
Pages: 937-943
Published online: 21 Nov 2020
AbstractforAML1-ETO inhibits acute myeloid leukemia immune escape by CD48 | Full Text | References | PDF (1.4 MB) | EPUB
  • 332 Views
  • 9 CrossRef citations
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Article
Comparison of fixed dose reduced-intensity conditioning with fludarabine and busulfan to PK-guided busulfan AUC (FluBu4K) in hematopoietic stem cell transplant for AML/MDS
Brendan Rasor, Tyler Dickerson, Qiuhong Zhao, Patrick Elder, Jonathan E. Brammer, Karilyn Larkin, Samantha Jaglowski, Alice Mims, Sam Penza, Sumithira Vasu, Sarah A. Wall, Basem William, Ayman Saad, Julianna V. F. Roddy, Hannah Choe & Marcin Puto
Pages: 944-951
Published online: 24 Nov 2020
AbstractforComparison of fixed dose reduced-intensity conditioning with fludarabine and busulfan to PK-guided busulfan AUC (FluBu4K) in hematopoietic stem cell transplant for AML/MDS | Full Text | References | PDF (1.2 MB) | EPUB
  • 216 Views
  • 1 CrossRef citations
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Article
Value of pre-transplant consolidation chemotherapy in adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation without minimal residual disease in first complete remission
Weijia Fu, Aijie Huang, Guihua Lu, Xiong Ni, Lei Gao, Li Chen, Jie Chen, Weiping Zhang & Jianmin Yang
Pages: 952-959
Published online: 11 Nov 2020
AbstractforValue of pre-transplant consolidation chemotherapy in adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation without minimal residual disease in first complete remission | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 201 Views
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Article
Distance to the pediatric oncology center does not affect survival in children with acute lymphoblastic leukemia: a report from CYP-C
Daphné Lemieux-Sarrasin, Marie-Claude Pelland-Marcotte, David Simonyan, Émilie Martineau, Barbara Desbiens & Bruno Michon
Pages: 960-966
Published online: 24 Nov 2020
AbstractforDistance to the pediatric oncology center does not affect survival in children with acute lymphoblastic leukemia: a report from CYP-C | Full Text | References | PDF (738.7 KB) | EPUB | Supplemental
  • 216 Views
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Article
The regulation of bcr-abl in hypoxia is through the mTOR pathway
Erin Clapper, Giovanna Di Trapani & Kathryn F. Tonissen
Pages: 967-978
Published online: 29 Nov 2020
AbstractforThe regulation of bcr-abl in hypoxia is through the mTOR pathway | Full Text | References | PDF (2.8 MB) | EPUB
  • 236 Views
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Letters to the Editor

Letter
Daratumumab is safe and induces a rapid hematological response in light-chain amyloidosis with severe cardiac impairment
Romain Gounot, Fabien Le Bras, Jehan Dupuis, Silvia Oghina, Diane Bodez, Louise Roulin, Alizee Maarek, Amandine Ladaique, Asma Beldi-Ferchiou, Elsa Poullot, Valerie Molinier-Frenkel, Corinne Haioun, Thibaud Damy, Karim Belhadj & François Lemonnier
Pages: 979-983
Published online: 29 Nov 2020
First Page PreviewforDaratumumab is safe and induces a rapid hematological response in light-chain amyloidosis with severe cardiac impairment | Full Text | References | PDF (513.8 KB) | EPUB | Supplemental
  • 282 Views
  • 3 CrossRef citations
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Letter
Severe ulcerative gastrointestinal toxicity following ibrutinib therapy: two case studies
Lucas Pacoureau, Mathilde De Menthon, Isabelle Boytchev, Thierry Lazure, Laurence Rocher, Olivier Lambotte & Nicolas Noël
Pages: 984-987
Published online: 12 Nov 2020
First Page PreviewforSevere ulcerative gastrointestinal toxicity following ibrutinib therapy: two case studies | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 171 Views
  • 2 CrossRef citations
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Letter
Mutational analysis in different foci revealing the clonal evolution of blastic plasmacytoid dendritic cell neoplasm
Xiang Zhang, Yanan Zhu, Min Yang, Lei Wang, Jie Jin & Wenjuan Yu
Pages: 988-991
Published online: 11 Nov 2020
First Page PreviewforMutational analysis in different foci revealing the clonal evolution of blastic plasmacytoid dendritic cell neoplasm | Full Text | References | PDF (1.1 MB) | EPUB
  • 179 Views
  • 1 CrossRef citations
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Letter
Severe treatment-resistant autoimmune haemolytic anaemia following ipilimumab in a patient with metastatic melanoma and CLL
Dale Jobson, Christopher J. McCormack, Emma Hiscutt & Constantine Tam
Pages: 992-994
Published online: 21 Nov 2020
First Page PreviewforSevere treatment-resistant autoimmune haemolytic anaemia following ipilimumab in a patient with metastatic melanoma and CLL | Full Text | References | PDF (493.1 KB) | EPUB
  • 160 Views
  • 3 CrossRef citations
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Letter
Allogeneic hematopoietic stem cell transplantation could improve survival for pure CBF-AML patients with minimal residual disease positive after the second consolidation
Tanzhen Wang, Biqi Zhou, Jubin Zhang, Xinyue Zhang, Tianhui Liu, Huiying Qiu, Aining Sun, Suning Chen, Depei Wu & Yang Xu
Pages: 995-998
Published online: 16 Nov 2020
AbstractforAllogeneic hematopoietic stem cell transplantation could improve survival for pure CBF-AML patients with minimal residual disease positive after the second consolidation | Full Text | References | PDF (695.2 KB) | EPUB
  • 287 Views
  • 5 CrossRef citations
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Evaluation of the effect of prospective biomarker testing on progression-free survival in diffuse large B-cell lymphoma
Edith Szafer-Glusman, Juan Liu, Arijit Sinha, Franklin V. Peale Jr, Jill Ray, Carsten Horn, Mikkel Z. Oestergaard, Martin Kornacker, Laurie H. Sehn, Umberto Vitolo, Andrea Knapp, Jeffrey Venstrom, Michelle Byrtek & Elizabeth Punnoose
Pages: 999-1002
Published online: 16 Dec 2020
First Page PreviewforEvaluation of the effect of prospective biomarker testing on progression-free survival in diffuse large B-cell lymphoma | Full Text | References | PDF (660.4 KB) | EPUB
  • 1018 Views
  • 0 CrossRef citations
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Open Access
Letter
Incidence, management and outcomes of arterial and venous thrombosis after chimeric antigen receptor modified T cells for B cell lymphoma and multiple myeloma
Anna L. Parks, Swetha Kambhampati, Bita Fakhri, Charalambos Andreadis, Lissa Gray, Sandy W. Wong, Nina Shah & Margaret C. Fang
Pages: 1003-1006
Published online: 01 Dec 2020
First Page PreviewforIncidence, management and outcomes of arterial and venous thrombosis after chimeric antigen receptor modified T cells for B cell lymphoma and multiple myeloma | Full Text | References | PDF (621.7 KB) | EPUB | Supplemental
  • 297 Views
  • 4 CrossRef citations
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Letter
Successful stem cell harvest and autologous transplantation in a patient with cold agglutinin syndrome and aggressive lymphoma
Alice Morigi, Beatrice Casadei, Lisa Argnani, Vittorio Stefoni, Emanuela Sergio, Michele Cavo & Pier Luigi Zinzani
Pages: 1007-1009
Published online: 04 Dec 2020
First Page PreviewforSuccessful stem cell harvest and autologous transplantation in a patient with cold agglutinin syndrome and aggressive lymphoma | Full Text | References | PDF (577.8 KB) | EPUB
  • 158 Views
  • 3 CrossRef citations
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Letter
Utility of 18F-FDG-PET/CT in lymphoblastic lymphoma
Thomas A Fox, Ben Carpenter, Mary Taj, Martha Perisoglou, Emma Nicholson, Anna Castleton, Johnathon Elliot, Ben Uttenthal, Callum Wright, Richard Halsey, Asim Khwaja, Victoria Grandage, Marc R Mansour, Adele K Fielding & Rachael Hough
Pages: 1010-1012
Published online: 04 Dec 2020
First Page PreviewforUtility of 18F-FDG-PET/CT in lymphoblastic lymphoma | Full Text | References | PDF (326.2 KB) | EPUB
  • 247 Views
  • 2 CrossRef citations
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Letter
Long-term outcomes of ocular adnexal lymphomas: case series from two lymphoma centers in Brazil
Mariana de Oliveira Marques, Paulo Goes Manso, Raphael L. C. Araujo, Fábio do Nascimento Brito, Jamille Elita de Castro Cunha Herculani, Giovanna Garzon Dias Lemos, Milena Almendra Rodrigues, Luiz Fernando Teixeira, Kleber Simões do Espirito Santo, Yara de Menezes, Karin Zattar Cecyn, Gisele W. Braga Colleoni & Otavio C. G. Baiocchi
Pages: 1013-1015
Published online: 18 Jan 2021
First Page PreviewforLong-term outcomes of ocular adnexal lymphomas: case series from two lymphoma centers in Brazil | Full Text | References | PDF (498 KB) | EPUB
  • 123 Views
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Letter
Response assessment and salvage indication for idiopathic multicentric Castleman disease
Chen Wang
Pages: 1016-1017
Published online: 20 Nov 2020
CitationforResponse assessment and salvage indication for idiopathic multicentric Castleman disease | Full Text | References | PDF (338 KB) | EPUB
  • 60 Views
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Letter
Restricted mean survival time in patients with chronic lymphocytic leukemia treated with chemotherapy-free regimens as first line
Andrea Messori & Laura Bartoli
Page: 1018
Published online: 09 Nov 2020
CitationforRestricted mean survival time in patients with chronic lymphocytic leukemia treated with chemotherapy-free regimens as first line | Full Text | References | PDF (388.7 KB) | EPUB
  • 110 Views
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Letter
Effect of polymorphism in base excision repair genes on outcomes in adults following myeloablative single-unit cord blood transplantation
Takaaki Konuma, Maki Oiwa-Monna, Masamichi Isobe, Seiko Kato, Kazuaki Yokoyama, Nozomi Yusa, Satoshi Takahashi & Arinobu Tojo
Pages: 1019-1021
Published online: 05 Nov 2019
First Page PreviewforEffect of polymorphism in base excision repair genes on outcomes in adults following myeloablative single-unit cord blood transplantation | Full Text | References | PDF (686.6 KB) | EPUB
  • 121 Views
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Letter
Very late acute myeloid leukemia relapse: clinical features, treatment and outcome
Sabrina Mariani, Silvia Maria Trisolini, Clara Minotti, Massimo Breccia, Claudio Cartoni, Maria Stefania De Propris, Giovanna Loglisci, Roberto Latagliata, Maria Zaira Limongi, Anna Maria Testi, Robin Foà & Saveria Capria
Pages: 1022-1025
Published online: 16 Jan 2020
First Page PreviewforVery late acute myeloid leukemia relapse: clinical features, treatment and outcome | Full Text | References | PDF (435.8 KB) | EPUB
  • 207 Views
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Letter
Real-life evaluation of potential candidates for treatment discontinuation in chronic myeloid leukemia: the impact of age and long-term follow-up
Emilia Scalzulli, Gioia Colafigli, Sara Pepe, Giulia De Luca, Alessio Di Prima, Fabio Efficace, Daniela Diverio, Roberto Latagliata, Maurizio Martelli, Robin Foà & Massimo Breccia
Pages: 1026-1027
Published online: 16 Aug 2020
CitationforReal-life evaluation of potential candidates for treatment discontinuation in chronic myeloid leukemia: the impact of age and long-term follow-up | Full Text | References | PDF (239.7 KB) | EPUB
  • 153 Views
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