Leukemia & Lymphoma, Volume 63, Issue 11 (2022)

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Leukemia & Lymphoma, Volume 63, Issue 11 (2022)

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Reviews

Review
Targeting the immune microenvironment in mantle cell lymphoma: implications for current and emerging therapies
David Qualls, Anita Kumar & Zachary D. Epstein-Peterson
Pages: 2515-2527
Published online: 15 Jun 2022
AbstractforTargeting the immune microenvironment in mantle cell lymphoma: implications for current and emerging therapies | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 364 Views
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Review
What constitutes meaningful improvement in myelodysplastic syndromes?
Namrata S. Chandhok & Mikkael A. Sekeres
Pages: 2528-2535
Published online: 14 Jun 2022
AbstractforWhat constitutes meaningful improvement in myelodysplastic syndromes? | Full Text | References | PDF (702.5 KB) | EPUB
  • 256 Views
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Review
Clonal hematopoiesis in clinical practice: walking a tightrope
Francesco Tarantini, Cosimo Cumbo, Luisa Anelli, Antonella Zagaria, Nicoletta Coccaro, Giuseppina Tota, Giorgina Specchia, Pellegrino Musto & Francesco Albano
Pages: 2536-2544
Published online: 13 Jun 2022
AbstractforClonal hematopoiesis in clinical practice: walking a tightrope | Full Text | References | PDF (1.1 MB) | EPUB
  • 272 Views
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Original Articles

Article
Investigating the potential molecular players and therapeutic drug molecules in carfilzomib resistant multiple myeloma by comprehensive bioinformatics analysis
Somnath Ghosal & Subrata Banerjee
Pages: 2545-2556
Published online: 14 Jun 2022
AbstractforInvestigating the potential molecular players and therapeutic drug molecules in carfilzomib resistant multiple myeloma by comprehensive bioinformatics analysis | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 337 Views
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Article
Real-world treatment patterns for patients with newly diagnosed multiple myeloma in Alberta, Canada
Victor H. Jimenez-Zepeda, Guanmin Chen, Eileen Shaw, Megan S. Farris, Tara Cowling & Jason Tay
Pages: 2557-2564
Published online: 05 Jul 2022
AbstractforReal-world treatment patterns for patients with newly diagnosed multiple myeloma in Alberta, Canada | Full Text | References | PDF (935.4 KB) | EPUB | Supplemental
  • 226 Views
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Article
SPAG5 as a novel biomarker and potential therapeutic target via regulating AKT pathway in multiple myeloma
Xinyi Zeng, Wenbin Xu, Jianjing Tong, Jia Liu, Zilu Zhang, Mei Liu, Chao Wu, Qing Yu, Chenjing Ye, Chengyu Wu, Yingli Wu & Hua Yan
Pages: 2565-2572
Published online: 22 Jun 2022
AbstractforSPAG5 as a novel biomarker and potential therapeutic target via regulating AKT pathway in multiple myeloma | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 315 Views
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Article
CD43 is an adverse prognostic factor in newly diagnosed multiple myeloma
Xueqin Ning, Xiaolei Wei, Bingyuan Chen, Zhen Li, Zhongxin Zheng, Zhengshan Yi, Qi Wei, Xutao Guo, Qiaoxi Kang, Ru Feng & Yongqiang Wei
Pages: 2573-2578
Published online: 12 Jul 2022
AbstractforCD43 is an adverse prognostic factor in newly diagnosed multiple myeloma | Full Text | References | PDF (635.8 KB) | EPUB
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Article
NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980–2017: a nationwide cohort study
Patrick R. G. Eriksen, Erik Clasen-Linde, Peter de Nully Brown, Laura Haunstrup, Mette Christoffersen, Peter Asdahl, Troels Møller Thomsen, Christian von Buchwald & Steffen Heegaard
Pages: 2579-2588
Published online: 14 Jun 2022
AbstractforNK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980–2017: a nationwide cohort study | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 175 Views
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Article
Role of high acquisition flow cytometry in the detection of marrow involvement in patients with extramedullary B cell non-Hodgkins lymphoma: a comparison with marrow aspirate cytology, trephine biopsy, and PET
Thulasi Raman Ramalingam, Anurekha Muthu, Archana Lakshmanan, Swetha Narla, Annapurneswari Subramanyan, Shelley Simon, Jayaraj Govindaraj, Lakshman Vaidhyanathan, Jose Easow & Thirumalairaj Raja
Pages: 2589-2596
Published online: 12 Jul 2022
AbstractforRole of high acquisition flow cytometry in the detection of marrow involvement in patients with extramedullary B cell non-Hodgkins lymphoma: a comparison with marrow aspirate cytology, trephine biopsy, and PET | Full Text | References | PDF (1.6 MB) | EPUB
  • 182 Views
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Article
Rituximab or rituximab plus chlorambucil for translocation (11;18)-negative gastric mucosa-associated lymphoid tissue lymphoma: a monocentric non-randomized observational study
Michaël Lévy, Jehan Dupuis, Cecile Charpy, Antoine Martin, Emmanuel Itti, Iradj Sobhani, Corinne Haioun & Aurelien Amiot
Pages: 2597-2603
Published online: 10 Jun 2022
AbstractforRituximab or rituximab plus chlorambucil for translocation (11;18)-negative gastric mucosa-associated lymphoid tissue lymphoma: a monocentric non-randomized observational study | Full Text | References | PDF (758.6 KB) | EPUB
  • 124 Views
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Article
Single-cell RNA sequencing to explore composition of peripheral blood NK cells in patients with chronic myeloid leukemia in treatment-free remission
Guopan Yu, Weixiang Lu, Xiaofan Chen, Yanlin Li, Jiaxin Long, Zhongxin Zheng, Changxin Yin & Dan Xu
Pages: 2604-2615
Published online: 11 Jun 2022
AbstractforSingle-cell RNA sequencing to explore composition of peripheral blood NK cells in patients with chronic myeloid leukemia in treatment-free remission | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
  • 414 Views
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Article
The prognostic role of NKG2A expression for patients with chronic myeloid leukemia after treatment discontinuation
Ziyao Xu, Jinyu Yin, Qian Sun, Jinhua Hu, Ming Hong, Sixuan Qian & Wenjie Liu
Pages: 2616-2626
Published online: 25 Jun 2022
AbstractforThe prognostic role of NKG2A expression for patients with chronic myeloid leukemia after treatment discontinuation | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 215 Views
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Article
Association of insurance types and outcomes in acute promyelocytic leukemia
Prajwal Dhakal, Utsav Joshi, Elizabeth Lyden, Avantika Pyakuryal, Krishna Gundabolu & Vijaya Raj Bhatt
Pages: 2627-2635
Published online: 23 Jun 2022
AbstractforAssociation of insurance types and outcomes in acute promyelocytic leukemia | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 131 Views
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Article
Effectiveness and safety of leukapheresis in hyperleukocytic leukemias: a retrospective multicenter study
Xiang Zhang, Yuqing Tu, Juan Shen, Yufeng Feng, Houshi Ma, Lian Bai, Xiaoli Li, Zhihong Lin, Lijun Dai, Feiran Gong, Tianyu Lu, Jiazi Zhou, Hanqing Chen, Quansheng Lv, Ziling Zhu & Changgeng Ruan
Pages: 2636-2644
Published online: 22 Jun 2022
AbstractforEffectiveness and safety of leukapheresis in hyperleukocytic leukemias: a retrospective multicenter study | Full Text | References | PDF (1.2 MB) | EPUB
  • 192 Views
  • 1 CrossRef citations
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Article
Retrospective analysis of three induction chemotherapy regimens in acute myeloid leukemia including CPX-351, cytarabine/daunorubicin with and without the addition of cladribine
Felix Klingler, Winfried H. Alsdorf, Susanne Ghandili, Christine Wolschke, Franziska Brauneck, Carsten Bokemeyer, Walter Fiedler, Franziska Modemann & Panagiotis Karagiannis
Pages: 2645-2651
Published online: 05 Jul 2022
AbstractforRetrospective analysis of three induction chemotherapy regimens in acute myeloid leukemia including CPX-351, cytarabine/daunorubicin with and without the addition of cladribine | Full Text | References | PDF (1.4 MB) | EPUB
  • 188 Views
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Article
Treatments of Ph-like acute lymphoblastic leukemia: a real-world retrospective analysis from a single large center in China
Guo-fa Xu, Li-min Liu, Man Wang, Zhi-bo Zhang, Jun-dan Xie, Hui-ying Qiu & Su-ning Chen
Pages: 2652-2662
Published online: 24 Jun 2022
AbstractforTreatments of Ph-like acute lymphoblastic leukemia: a real-world retrospective analysis from a single large center in China | Full Text | References | PDF (1.6 MB) | EPUB
  • 331 Views
  • 2 CrossRef citations
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Article
Solving coagulation conundrums: comparing prophylaxis strategies in adult patients receiving PEG-asparaginase
YeeAnn Chen, Kaitlyn Buhlinger, Anthony J. Perissinotti, Allison J. Schepers, Lydia Benitez, Jessica Auten, Sheh-Li Chen, Dale L. Bixby, Patrick W. Burke, Kristen M. Pettit & Bernard L. Marini
Pages: 2663-2670
Published online: 14 Jun 2022
AbstractforSolving coagulation conundrums: comparing prophylaxis strategies in adult patients receiving PEG-asparaginase | Full Text | References | PDF (725.1 KB) | EPUB
  • 294 Views
  • 1 CrossRef citations
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Article
Outcomes after venetoclax with hypomethylating agents in myelodysplastic syndromes: a systematic review and meta-analysis
Razwana Khanam, Moazzam Shahzad, Sibgha Gull Chaudhary, Fatima Ali, Zunairah Shah, Pranali S. Pachika, Zahoor Ahmed, Asmi Chattaraj, Adeel Masood, Nausheen Ahmed, Rajat Bansal, Ramesh Balusu, Leyla Shune, Faiz Anwar, Peiman Hematti, Joseph P. McGuirk, Abdulraheem Yacoub & Muhammad Umair Mushtaq
Pages: 2671-2678
Published online: 10 Jun 2022
AbstractforOutcomes after venetoclax with hypomethylating agents in myelodysplastic syndromes: a systematic review and meta-analysis | Full Text | References | PDF (1.8 MB) | EPUB
  • 556 Views
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Article
Post-transplant cyclophosphamide pharmacokinetics and haploidentical hematopoietic cell transplantation outcomes: an exploratory study
Kripa Shanker Kasudhan, Amol N. Patil, Aditya Jandial, Alka Khadwal, Gaurav Prakash, Arihant Jain, Dinesh Bhurani, Rayaz Ahmed, Narendra Agrawal, Reema Singh, Man Updesh Singh Sachdeva, Neelam Varma, Reena Das, Savita Verma Attri, Samir Malhotra, Navneet S. Majhail, Pankaj Malhotra & Deepesh P. Lad
Pages: 2679-2685
Published online: 14 Jun 2022
AbstractforPost-transplant cyclophosphamide pharmacokinetics and haploidentical hematopoietic cell transplantation outcomes: an exploratory study | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 674 Views
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Letters to the Editor

Letter
Characteristics of SARS-CoV-2 infection in lymphoma/chronic lymphocytic leukemia patients during the Omicron outbreak
Milena Kohn, Tamim Alsuliman, Sylvain Lamure, Morgane Cheminant, Jéremy Delage, Corinne Merle De Boever, Jean Jacques Tudesq, Zora Marjanovic, Zoé Van de Wyngaert, Florent Malard, Eolia Brissot, Sophie Rigaudeau, Stéphanie Marque-Juillet, Audrey Therby, Guillaume Cartron, Philippe Rousselot, Olivier Hermine, Rémy Duléry & Caroline Besson
Pages: 2686-2690
Published online: 18 Jun 2022
First Page PreviewforCharacteristics of SARS-CoV-2 infection in lymphoma/chronic lymphocytic leukemia patients during the Omicron outbreak | Full Text | References | PDF (755.7 KB) | EPUB | Supplemental
  • 253 Views
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Letter
Poor clinical outcome of elderly patients with primary plasma cell leukemia treated with novel agents: real-world experience
Masuho Saburi, Masanori Sakata, Hiroyuki Takata, Yasuhiko Miyazaki, Katsuya Kawano, Hitohiro Sasaki, Miyuki Abe, Kazuhiro Kohno, Yasuhiro Soga, Kentaro Nagamatsu, Keiji Ono, Toshiyuki Nakayama & Eiichi Ohtsuka
Pages: 2691-2695
Published online: 10 Jun 2022
First Page PreviewforPoor clinical outcome of elderly patients with primary plasma cell leukemia treated with novel agents: real-world experience | Full Text | References | PDF (721.2 KB) | EPUB
  • 105 Views
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Letter
The clinical outcomes of mixed engraftment patients treated with haploidentical stem cells combined with umbilical cord blood transplantation
Yujie Liu, Lijuan Qi, Tanzhen Wang, Biqi Zhou, Jia Chen, Jinyan Xiao, Yanglan Fang, Qiannan Yang, Yufeng Feng, Depei Wu & Yang Xu
Pages: 2696-2700
Published online: 18 Jun 2022
First Page PreviewforThe clinical outcomes of mixed engraftment patients treated with haploidentical stem cells combined with umbilical cord blood transplantation | Full Text | References | PDF (983 KB) | EPUB | Supplemental
  • 69 Views
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Letter
Impact of SF3B1 mutation in myelofibrosis
Jayastu Senapati, Srdan Verstovsek, Lucia Masarova, Naveen Pemmaraju, Keyur P. Patel, Guillermo Montalban-Bravo, Sherry A. Pierce, Lingsha Zhou, Guillermo Garcia-Manero, Hagop M. Kantarjian & Prithviraj Bose
Pages: 2701-2705
Published online: 05 Jul 2022
First Page PreviewforImpact of SF3B1 mutation in myelofibrosis | Full Text | References | PDF (1.2 MB) | EPUB
  • 242 Views
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Letter
Profound response to venetoclax monotherapy in a patient with BCL-2 positive relapsed multiple myeloma and extramedullary CNS manifestations
David M. Cordas dos Santos, Tanja Paul, Wolfgang G. Kunz, Martina Rudelius & Sebastian Theurich
Pages: 2706-2710
Published online: 06 Jul 2022
First Page PreviewforProfound response to venetoclax monotherapy in a patient with BCL-2 positive relapsed multiple myeloma and extramedullary CNS manifestations | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 199 Views
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Letter
Phase 1b, open-label study evaluating the safety and pharmacokinetics of atezolizumab (anti–PD-L1 antibody) administered in combination with Hu5F9-G4 to patients with relapsed and/or refractory acute myeloid leukemia
Naval Daver, Brian A. Jonas, Bruno C. Medeiros, Upen Patil & Mark Yan
Pages: 2711-2714
Published online: 14 Jul 2022
First Page PreviewforPhase 1b, open-label study evaluating the safety and pharmacokinetics of atezolizumab (anti–PD-L1 antibody) administered in combination with Hu5F9-G4 to patients with relapsed and/or refractory acute myeloid leukemia | Full Text | References | PDF (630 KB) | EPUB | Supplemental
  • 300 Views
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Letter
TCF1 and Tox define different subsets of CD4 T cells in patients with Sézary syndrome
Maria Wysocka, Neha Jariwala, Kevin Zhang, Bernice Benoit & Alain H. Rook
Pages: 2715-2718
Published online: 09 Jun 2022
First Page PreviewforTCF1 and Tox define different subsets of CD4 T cells in patients with Sézary syndrome | Full Text | References | PDF (724.2 KB) | EPUB
  • 273 Views
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Letter
Classic Hodgkin lymphoma cloaked in an intense sarcoid-like reaction
Hamza Tariq
Pages: 2719-2722
Published online: 27 May 2022
First Page PreviewforClassic Hodgkin lymphoma cloaked in an intense sarcoid-like reaction | Full Text | References | PDF (1 MB) | EPUB
  • 87 Views
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Letter
Clinicopathological factors affecting prognosis in marginal zone lymphoma in Asian patients: a cohort study
Yao Hao Teo, Yao Neng Teo, Lay Poh Khoo, Esther Wei Yin Chang, Ya Hwee Tan, Jianbang Chiang, Valerie Shiwen Yang, Eileen Poon, Nagavalli Somasundaram, Mohamad Farid, Miriam Tao, Soon Thye Lim & Jason Yongsheng Chan
Pages: 2723-2726
Published online: 10 Jun 2022
First Page PreviewforClinicopathological factors affecting prognosis in marginal zone lymphoma in Asian patients: a cohort study | Full Text | References | PDF (642.8 KB) | EPUB | Supplemental
  • 114 Views
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Letter
Optimizing pegaspargase therapy in patients with hypersensitivity reactions
Divya Subburaj, Ketan Kulkarni & Tamara MacDonald
Pages: 2727-2730
Published online: 21 Jun 2022
First Page PreviewforOptimizing pegaspargase therapy in patients with hypersensitivity reactions | Full Text | References | PDF (527.2 KB) | EPUB | Supplemental
  • 167 Views
  • 1 CrossRef citations
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Letter
Hyperleukocytosis associated with delayed presentation among patients with acute leukemia during the COVID-19 pandemic
Aditya Tedjaseputra, James A. Kuzich, Nisha Thiagarajah, Tse-Chieh Teh, Julia McClelland, Marzia Rahman, Rowena Brook, Chong Chyn Chua, Doen Ming Ong, Shuh-Ying Tan, Robin Filshie, Chun Yew Fong, Pasquale Fedele, Ashish Bajel, Jake Shortt & Andrew H. Wei
Pages: 2731-2734
Published online: 21 Jun 2022
First Page PreviewforHyperleukocytosis associated with delayed presentation among patients with acute leukemia during the COVID-19 pandemic | Full Text | References | PDF (1,005.4 KB) | EPUB | Supplemental
  • 146 Views
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Letter
TP53/PLCG2-mutated diffuse large B-cell lymphoma richter transformation (DLBCL-RT) of CLL with unusual CD2 and PD-1 expression
Emily Symes, Peng Wang, Angela M. Lager, Michael R. Bishop, Barina Aqil & Girish Venkataraman
Pages: 2735-2738
Published online: 18 Jun 2022
First Page PreviewforTP53/PLCG2-mutated diffuse large B-cell lymphoma richter transformation (DLBCL-RT) of CLL with unusual CD2 and PD-1 expression | Full Text | References | PDF (1.1 MB) | EPUB
  • 360 Views
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Letter
Outcomes after initial refusal of curative treatment in patients with classic Hodgkin lymphoma
Manik Chahal, Anna Hayden, Kerry J. Savage, Diego Villa, David W. Scott, Alina S. Gerrie, Andrea Lo, Matthew Chan, Tom Pickles, Joseph M. Connors, Laurie Helen Sehn & Ciara L. Freeman
Pages: 2739-2742
Published online: 24 Jun 2022
First Page PreviewforOutcomes after initial refusal of curative treatment in patients with classic Hodgkin lymphoma | Full Text | References | PDF (1.3 MB) | EPUB
  • 81 Views
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Letter
Off-label venetoclax in combination with hypomethylating agents for post-allogeneic stem cell transplant acute myeloid leukemia relapse
Fabio Serpenti, Mariarita Sciumè, Giulia Galassi, Giorgia Saporiti, Federica Grifoni, Nicolò Rampi, Francesca Cavallaro, Kordelia Barbullushi, Elena Tagliaferri, Maria Goldaniga, Luca Baldini, Nicola Stefano Fracchiolla & Francesco Onida
Pages: 2743-2746
Published online: 22 Jun 2022
First Page PreviewforOff-label venetoclax in combination with hypomethylating agents for post-allogeneic stem cell transplant acute myeloid leukemia relapse | Full Text | References | PDF (634 KB) | EPUB
  • 186 Views
  • 1 CrossRef citations
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Letter
First report of bilateral breast-implant associated anaplastic large cell lymphoma caused by identical T-cell clone
Robert Stuver, Natasha E. Lewis, Mark D. Ewalt, Ahmet Dogan, Benjamin H. Durham, George Plitas, Colleen McCarthy & Steven M. Horwitz
Pages: 2747-2750
Published online: 25 Jun 2022
First Page PreviewforFirst report of bilateral breast-implant associated anaplastic large cell lymphoma caused by identical T-cell clone | Full Text | References | PDF (1 MB) | EPUB
  • 147 Views
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Letter
Sequential occurrence of chronic myeloproliferative and lymphoproliferative neoplasms: a collaborative retrospective study by pH-negative MPN latial group
Massimo Breccia, Luca Petriccione, Caterina Tatarelli, Marianna De Muro, Malgorzata Monica Trawinska, Michelina Santopietro, Antonio Spadea, Ambra Di Veroli, Emilia Scalzulli, Katia Paciaroni, Agostino Tafuri, Roberto Latagliata, Alessandro Andriani & Arianna Di Napoli
Pages: 2751-2753
Published online: 25 Jun 2022
First Page PreviewforSequential occurrence of chronic myeloproliferative and lymphoproliferative neoplasms: a collaborative retrospective study by pH-negative MPN latial group | Full Text | References | PDF (515.8 KB) | EPUB
  • 61 Views
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Letter
The safety of concurrent intrathecal chemotherapy during blinatumomab in adults with acute lymphoblastic leukemia
Dat Ngo, Salman Otoukesh, Anthony S. Stein, Stephen Forman, Vinod Pullarkat & Ibrahim Aldoss
Pages: 2754-2756
Published online: 21 Jun 2022
First Page PreviewforThe safety of concurrent intrathecal chemotherapy during blinatumomab in adults with acute lymphoblastic leukemia | Full Text | References | PDF (618 KB) | EPUB
  • 366 Views
  • 2 CrossRef citations
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Letter
Treatment patterns and outcomes of patients with CNS involvement of blastic plasmacytoid dendritic cell neoplasm (BPDCN)
James A. Davis, David A. Rizzieri, Andrew A. Lane, Justin Taylor, Muhammad Salman Faisal, Sumithira Vasu, Deborah Soong, Hong Li, Amanda Herbst & I. Brian Greenwell
Pages: 2757-2759
Published online: 21 Jun 2022
First Page PreviewforTreatment patterns and outcomes of patients with CNS involvement of blastic plasmacytoid dendritic cell neoplasm (BPDCN) | Full Text | References | PDF (471.2 KB) | EPUB
  • 345 Views
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Letter
Ixazomib and dexamethasone in high risk smoldering multiple myeloma: a clinical and correlative pilot study
Sham Mailankody, Meghan Salcedo, Elizabet Tavitian, Miranda Burge, Neha Korde, Hani Hassoun, Alexander Lesokhin, Oscar Lahoud, Eric Smith, Malin Hultcrantz, Carlyn Tan, Urvi Shah, Sean Devlin & Ola Landgren
Pages: 2760-2761
Published online: 15 Jul 2022
CitationforIxazomib and dexamethasone in high risk smoldering multiple myeloma: a clinical and correlative pilot study | Full Text | References | PDF (1.1 MB) | EPUB
  • 188 Views
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