Pharmaceutical Development and Technology, Volume 27, Issue 10 (2022)

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Pharmaceutical Development and Technology, Volume 27, Issue 10 (2022)

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Research Articles

Article
Development of ezetimibe eutectic with improved biopharmaceutical and mechanical properties to design an optimized oral solid dosage formulation
Parag Roy, Nimmy Kumari, Noopur Pandey, Abhishek Gour, Amit Raj, B. Srividya, Utpal Nandi & Animesh Ghosh
Pages: 989-998
Published online: 08 Nov 2022
AbstractforDevelopment of ezetimibe eutectic with improved biopharmaceutical and mechanical properties to design an optimized oral solid dosage formulation | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
Supercritical CO2 versus water as an antisolvent in the crystallization process to enhance dissolution rate of curcumin
Fatemeh Sadeghi, Hossein Kamali, Sepideh Kouhestanian, Farzin Hadizadeh, Ali Nokhodchi & Hadi Afrasiabi Garekani
Pages: 999-1008
Published online: 10 Nov 2022
AbstractforSupercritical CO2 versus water as an antisolvent in the crystallization process to enhance dissolution rate of curcumin | Full Text | References | PDF (2.7 MB) | EPUB
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Open Access
Article
In-line monitoring of solid dispersion preparation in small scale extrusion based on UV–vis spectroscopy
Judith Winck, Marvin Daalmann, Andreas Berghaus & Markus Thommes
Pages: 1009-1015
Published online: 12 Nov 2022
AbstractforIn-line monitoring of solid dispersion preparation in small scale extrusion based on UV–vis spectroscopy | Full Text | References | PDF (1.4 MB) | EPUB
  • 131 Views
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Article
Preparation and in vitro–in vivo evaluation of QbD based acemetacin loaded transdermal patch formulations for rheumatic diseases
Ece Özcan Bülbül, Hasan Ali Husseın, Gizem Yeğen, Mehmet Evren Okur, Neslihan Üstündağ Okur & Neşe Buket Aksu
Pages: 1016-1026
Published online: 30 Dec 2022
AbstractforPreparation and in vitro–in vivo evaluation of QbD based acemetacin loaded transdermal patch formulations for rheumatic diseases | Full Text | References | PDF (1.9 MB) | EPUB
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Article
Ritonavir nanosuspensions prepared by microfluidization with enhanced solubility and desirable immunological properties
Alptug Karakucuk, Hande Canpinar & Nevin Celebi
Pages: 1027-1037
Published online: 14 Nov 2022
AbstractforRitonavir nanosuspensions prepared by microfluidization with enhanced solubility and desirable immunological properties | Full Text | References | PDF (2.4 MB) | EPUB
  • 220 Views
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Article
Improved uptake and bioavailability of cinnamaldehyde via solid lipid nanoparticles for oral delivery
Long Wu, Yun Meng, Yuhang Xu & Xiaoqin Chu
Pages: 1038-1048
Published online: 24 Nov 2022
AbstractforImproved uptake and bioavailability of cinnamaldehyde via solid lipid nanoparticles for oral delivery | Full Text | References | PDF (2.3 MB) | EPUB
  • 166 Views
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Article
Co-delivery of docetaxel and p53 gene from cationic nanoparticles based on poly (l-lactide) and low-molecular-weight polyethyleneimine (PEA)
Qingfa Guo, Fanyuan Kong, Xiaoru Pan & Shuhua Cao
Pages: 1049-1056
Published online: 30 Nov 2022
AbstractforCo-delivery of docetaxel and p53 gene from cationic nanoparticles based on poly (l-lactide) and low-molecular-weight polyethyleneimine (PEA) | Full Text | References | PDF (2 MB) | EPUB
  • 87 Views
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Article
Mechanistic modelling of targeted pulmonary delivery of dactinomycin iron oxide-loaded nanoparticles for lung cancer therapy
Shahd F. Al-Tarawneh, Eman Zmaily Dahmash, Hamad Alyami, Suha M. Abu-Doleh, Samer Al-Ali, Affiong Iyire & Rasha Abuthawabeh
Pages: 1057-1068
Published online: 16 Dec 2022
AbstractforMechanistic modelling of targeted pulmonary delivery of dactinomycin iron oxide-loaded nanoparticles for lung cancer therapy | Full Text | References | PDF (2.4 MB) | EPUB
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Article
Effect of drug load and lipid–wax blends on drug release and stability from spray-congealed microparticles
Hongyi Ouyang, Soon Jun Ang, Zong Yang Lee, Tze Ning Hiew, Paul Wan Sia Heng & Lai Wah Chan
Pages: 1069-1082
Published online: 01 Dec 2022
AbstractforEffect of drug load and lipid–wax blends on drug release and stability from spray-congealed microparticles | Full Text | References | PDF (3.2 MB) | EPUB
  • 75 Views
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Article
Hydrolysis kinetics of the prodrug myristyl nicotinate
Bashar Altaani, Razan Haddad, Aliaa Al-Tarakji & Nasr Alrabadi
Pages: 1083-1092
Published online: 09 Dec 2022
AbstractforHydrolysis kinetics of the prodrug myristyl nicotinate | Full Text | References | PDF (1.4 MB) | EPUB
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Article
A multivariate data analysis approach to tablet sticking on an industrial scale: a qualitative case study of an ibuprofen-based formulation
Mahamadou Dembélé, Sophie Hudon, Jean-Sébastien Simard, Nicolas Abatzoglou & Ryan Gosselin
Pages: 1093-1109
Published online: 20 Dec 2022
AbstractforA multivariate data analysis approach to tablet sticking on an industrial scale: a qualitative case study of an ibuprofen-based formulation | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Ectoine gel transdermal formulation as a novel therapeutic approach in melanoma using 3D printed microneedles
Sammar A. Bayoumi, Aya M. Dawaba, Ahmed Mansour, Zeinab AlKasaby Zalat & Amal A. Ammar
Pages: 1110-1124
Published online: 16 Dec 2022
AbstractforEctoine gel transdermal formulation as a novel therapeutic approach in melanoma using 3D printed microneedles | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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