Pharmaceutical Development and Technology, Volume 6, Issue 2 (2001)

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Pharmaceutical Development and Technology, Volume 6, Issue 2 (2001)

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Research Article

Article
Effect of Processing Methods and Heat Treatment on the Formation of Wax Matrix Tablets for Sustained Drug Release
Yu-E Zhang, Ruy Tchao & Joseph B. Schwartz
Pages: 131-144
Published online: 30 Apr 2001
AbstractforEffect of Processing Methods and Heat Treatment on the Formation of Wax Matrix Tablets for Sustained Drug Release | Full Text | References | PDF (2.9 MB)
  • 197 Views
  • 35 CrossRef citations
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Article
Solubilization and Stability of Bumetanide in Vehicles for Intranasal Administration, a Pilot Study
Hanne W. Nielsen, Erik Bechgaard, Bettina Twile, Erik Didriksen & Gunvor T. Almtorp
Pages: 145-149
Published online: 30 Apr 2001
AbstractforSolubilization and Stability of Bumetanide in Vehicles for Intranasal Administration, a Pilot Study | Full Text | References | PDF (109.7 KB)
  • 197 Views
  • 3 CrossRef citations
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Article
Freeze Drying Properties of Some Oligonucleotides
Feroz Jameel, Kent L. Amsberry & Michael J. Pikal
Pages: 151-157
Published online: 30 Apr 2001
First Page PreviewforFreeze Drying Properties of Some Oligonucleotides | Full Text | References | PDF (134.1 KB)
  • 201 Views
  • 4 CrossRef citations
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Article
The Influence of Excipients on the Stability of the Moisture Sensitive Drugs Aspirin and Niacinamide: Comparison of Tablets Containing Lactose Monohydrate with Tablets Containing Anhydrous Lactose
Jianping Du & Stephen W. Hoag
Pages: 159-166
Published online: 30 Apr 2001
AbstractforThe Influence of Excipients on the Stability of the Moisture Sensitive Drugs Aspirin and Niacinamide: Comparison of Tablets Containing Lactose Monohydrate with Tablets Containing Anhydrous Lactose | Full Text | References | PDF (138.1 KB)
  • 771 Views
  • 30 CrossRef citations
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Article
A Novel Approach to Increase Oral Drug Absorption
Nasir M. Idkaidek & Nabil Abdel-Jabbar
Pages: 167-171
Published online: 30 Apr 2001
AbstractforA Novel Approach to Increase Oral Drug Absorption | Full Text | References | PDF (110.8 KB)
  • 27 Views
  • 0 CrossRef citations
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Article
Release Behavior of Ketoprofen from Poly(Acryloyl-L-proline Methyl Ester) Gels Having Different Crosslinked Networks
Munehiro Negishi, Akihiro Hiroki, Yoichiro Horikoshi, Masaharu Miyajima, Yasunari Maekawa, Ryoichi Katakai & Masaru Yoshida
Pages: 173-179
Published online: 30 Apr 2001
AbstractforRelease Behavior of Ketoprofen from Poly(Acryloyl-L-proline Methyl Ester) Gels Having Different Crosslinked Networks | Full Text | References | PDF (364.8 KB)
  • 26 Views
  • 1 CrossRef citations
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Article
End-Point Detection in a Wet Granulation Process
Per Holm, Torben Schaefer & Crilles Larsen
Pages: 181-192
Published online: 30 Apr 2001
AbstractforEnd-Point Detection in a Wet Granulation Process | Full Text | References | PDF (668.7 KB)
  • 648 Views
  • 26 CrossRef citations
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Article
Influence of Elastic Deformation of Particles on Heckel Analysis
Changquan Sun & David J. W. Grant
Pages: 193-200
Published online: 30 Apr 2001
AbstractforInfluence of Elastic Deformation of Particles on Heckel Analysis | Full Text | References | PDF (132.7 KB)
  • 1375 Views
  • 84 CrossRef citations
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Article
Effervescent Atomization of Aqueous Polymer Solutions and Dispersions
Frederik J. Petersen, Ole Wørts, Torben Schæfer & Paul E. Sojka
Pages: 201-210
Published online: 30 Apr 2001
AbstractforEffervescent Atomization of Aqueous Polymer Solutions and Dispersions | Full Text | References | PDF (218.6 KB)
  • 156 Views
  • 21 CrossRef citations
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Article
Influence of Film Additives on Stabilizing Drug Release Rates from Pellets Coated with Acrylic Polymers
Toru Maejima & James W. McGinity
Pages: 211-221
Published online: 30 Apr 2001
AbstractforInfluence of Film Additives on Stabilizing Drug Release Rates from Pellets Coated with Acrylic Polymers | Full Text | References | PDF (447.2 KB)
  • 249 Views
  • 44 CrossRef citations
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Article
Stability of Extruded 17β-Estradiol Solid Dispersions
Stefan Hülsmann, Thomas Backensfeld & Roland Bodmeier
Pages: 223-229
Published online: 30 Apr 2001
AbstractforStability of Extruded 17β-Estradiol Solid Dispersions | Full Text | References | PDF (171.1 KB)
  • 182 Views
  • 18 CrossRef citations
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Article
Preparation and Release Characteristics of Protein-Loaded Polyanion/Gelatin Complex
H. L. Jiang & K. J. Zhu
Pages: 231-240
Published online: 30 Apr 2001
AbstractforPreparation and Release Characteristics of Protein-Loaded Polyanion/Gelatin Complex | Full Text | References | PDF (150.5 KB)
  • 38 Views
  • 2 CrossRef citations
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Article
Monitoring the Retention of a Protein Antigen in Complete Freund's Adjuvant, Alum, and Pluronic F-127 Gel Formulations by X-ray Fluorescence
Donald S. MacLean, J. David Robertson & Michael Jay
Pages: 241-246
Published online: 30 Apr 2001
AbstractforMonitoring the Retention of a Protein Antigen in Complete Freund's Adjuvant, Alum, and Pluronic F-127 Gel Formulations by X-ray Fluorescence | Full Text | References | PDF (123.2 KB)
  • 65 Views
  • 4 CrossRef citations
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Article
Effects of Formulation Variables and Post-compression Curing on Drug Release from a New Sustained-Release Matrix Material: Polyvinylacetate-Povidone
Zezhi J. Shao, Mohammad I. Farooqi, Steven Diaz, Aravind K. Krishna & Nouman A. Muhammad
Pages: 247-254
Published online: 30 Apr 2001
AbstractforEffects of Formulation Variables and Post-compression Curing on Drug Release from a New Sustained-Release Matrix Material: Polyvinylacetate-Povidone | Full Text | References | PDF (250.7 KB)
  • 274 Views
  • 23 CrossRef citations
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Article
Characterization of a Backbone Cleavage Product of BMS-196854 (Oncostatin M), a Recombinant Anti-inflammatory Cytokine
Fang Zhao, Daniel J. Stein, Mehdi Paborji, Patricia W. Cash, Barbara J. Root, Ziping Wei & Corey J. Knupp
Pages: 255-261
Published online: 30 Apr 2001
AbstractforCharacterization of a Backbone Cleavage Product of BMS-196854 (Oncostatin M), a Recombinant Anti-inflammatory Cytokine | Full Text | References | PDF (135.8 KB)
  • 38 Views
  • 1 CrossRef citations
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Article
Properties of Tablets Containing Granulations of Ibuprofen and an Acrylic Copolymer Prepared by Thermal Processes
Motonori Kidokoro, Navnit H. Shah, A. Waseem Malick, Martin H. Infeld & James W. McGinity
Pages: 263-275
Published online: 30 Apr 2001
AbstractforProperties of Tablets Containing Granulations of Ibuprofen and an Acrylic Copolymer Prepared by Thermal Processes | Full Text | References | PDF (935.2 KB)
  • 258 Views
  • 29 CrossRef citations
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Article
The Effects of Plasticizers and Titanium Dioxide on the Properties of Poly(Vinyl Alcohol) Coatings
E. R. Hsu, M. S. Gebert, N. T. Becker & A. L. Gaertner
Pages: 277-284
Published online: 30 Apr 2001
AbstractforThe Effects of Plasticizers and Titanium Dioxide on the Properties of Poly(Vinyl Alcohol) Coatings | Full Text | References | PDF (130 KB)
  • 132 Views
  • 10 CrossRef citations
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Article
Drugs of the Future: Lessons of the Past
Michael J. Akers Editor
Pages: v-vi
Published online: 30 Apr 2001
First Page PreviewforDrugs of the Future: Lessons of the Past | Full Text | PDF (58.3 KB)
  • 17 Views
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