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Research Article

Article
In-silico green toxicology approach toward discovering safer ligands for development of safe-by-design metal–organic frameworks
Reyhane Khezri, Seyed Jamaleddin Shahtaheri, Elahe Khezri, Mahdi Niknam Shahrak & Monireh Khadem
Published online: 23 May 2024
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Research Article

Article
Effects of organophosphates on precision-cut kidney slices
C. Hoeffner, F. Worek & N. Amend
Published online: 23 May 2024
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Research Article

Article
Evaluating the possible genotoxicity of nanoaluminum incorporated in human vaccines and the potential protective role of nanocurcumin: an in vivo study
Nevine Khairy Elkady, Abrar Roshdy Abouelkheir, Sherien S. Ghaleb, Olfat Gamil Shaker, Heba Abd ElMonem Ibrahim, Eman Mohamed Ibraheim Moawad & Asmaa Mohammad Moawad
Published online: 22 May 2024
  • 24 Views
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Research Article

Article
Effects of acute carbon monoxide poisoning on liver damage and comparisons of related oxygen therapies in a rat model
Gul Sahika Gokdemir, Ugur Seker, Berjan Demirtas & Seyhan Taskin
Published online: 22 May 2024
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Research Article

Article
Enhanced Kidney Damage Induced by Increasing Nonylphenol Doses: Impact on Autophagy-Related Proteins and Proinflammatory Cytokines in Rats
Betul Yalcın, Gozde Ozge Onder, Ozge Goktepe, Pınar Alisan Suna, Ozge Cengiz Mat, Eda Koseoglu, Emre Cetindag, Munevver Baran, Nazmiye Bitgen, Özlem Öz Gergı̇n & Arzu Yay
Accepted author version posted online: 21 May 2024
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Research Article

Article
Obesity aggravates neuroinflammatory and neurodegenerative effects of bisphenol A in female rats
Anuradha Mangla, Poonam Goswami, Bhaskar Sharma, Suramya Suramya, Garima Jindal, Mehjbeen Javed, Mohd. Anas Saifi, Suhel Parvez, Tapas Chandra Nag & Sheikh Raisuddin
Published online: 16 May 2024
  • 117 Views
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Correction

Correction
Correction
Published online: 14 May 2024
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Free Access

Research Article

Article
Farnesoid X receptor modulator 12β-(m-methyl-benzoyl)-11,12-dihydro oleanolic acid represses liver fibrosis by inhibiting ERK/p38 signaling pathways
Yiming Li, Yunyang Bao, Simin Guo, Yang Li, Weishuo Fang, Na Zhang & Hongwei He
Published online: 14 May 2024
  • 52 Views
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Research Article

Article
Silver nanoparticle-induced cell damage via impaired mtROS-JNK/MnSOD signaling pathway
Mei Jing Piao, Kyoung Ah Kang, Pincha Devage Sameera Madushan Fernando, Herath Mudiyanselage Udari Lakmini Herath & Jin Won Hyun
Published online: 13 May 2024
  • 151 Views
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Open Access

Research Article

Article
Quercetin induces ferroptosis by inactivating mTOR/S6KP70 pathway in oral squamous cell carcinoma
Ya-Wen Zhu, Chun-Lei Liu, Xiao-Mei Li & Yu Shang
Published online: 12 May 2024
  • 38 Views
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Research Article

Article
Flow-through imaging and automated analysis of oil-exposed early stage Atlantic cod (Gadus morhua)
David R. Williamson, Emlyn J. Davies, Martin Ludvigsen & Bjørn Henrik Hansen
Published online: 24 Apr 2024
  • 154 Views
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Open Access

Research Article

Article
Assessment of TGx-DDI genes for genotoxicity in a comprehensive panel of chemicals
A. Rasim Barutcu
Published online: 15 Apr 2024
  • 41 Views
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Research Article

Article
A QSAR study for predicting malformation in zebrafish embryo
Mahsa Daneshmand, Jamileh SalarAmoli & Negin BaghbanZadeh
Published online: 15 Apr 2024
  • 62 Views
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Research Article

Article
Does the accounting of the local symmetry fragments in quasi-SMILES improve the predictive potential of the QSAR models of toxicity toward tadpoles?
Alla P. Toropova, Andrey A. Toropov, Alessandra Roncaglioni & Emilio Benfenati
Published online: 08 Apr 2024
  • 144 Views
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Open Access

Research Article

Article
Investigation of the effects of Theranekron and Sorafenib treatments on carcinogenesis, apoptosis and biochemical profile in hepatocellular carcinoma in rats
Serdar Vanli, Firuze Kurtoglu, Beyza S. Alan, Gokhan Akcakavak & Ozgur Ozdemir
Published online: 05 Apr 2024
  • 108 Views
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Research Article

Article
Isoflurane pretreatment protects against myocardial ischemia/reperfusion injury via mediating lncRNA CASC15/miR-542-3p axis
Xiaoyi Wang, Yueping Wang, Yawei Yuan, Long Wang & Dawei Zhang
Published online: 04 Apr 2024
  • 52 Views
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REVIEW ARTICLE

Review Article
Drug reactive metabolite-induced hepatotoxicity: a comprehensive review
Piyush Mahajan, Mahesh Palkar & Ravindra Babu Pingili
Published online: 01 Apr 2024
  • 116 Views
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Research Article

Article
Modulating oxidative stress, apoptosis, and mitochondrial dysfunctions on cardiotoxicity induced by aluminum phosphide pesticide using resveratrol
Deema K. Sabir, Abeer Al-Masri, Munirah F. Aldayel & Abeer A. Sharaf
Published online: 27 Mar 2024
  • 73 Views
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Research Article

Article
Neuroprotective effect of taxifolin against aluminum chloride-induced dementia and pathological alterations in the brain of rats: possible involvement of toll-like receptor 4
Bhagawati Saxena, Pragnesh Parmar, Heena Chauhan, Pooja Singh, Ashok Kumar Datusalia, Vivek Kumar Vyas, Nagja Tripathi & Jigna Shah
Published online: 25 Mar 2024
  • 80 Views
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Research Article

Article
Renoprotective effect of hyperin against CdCl2 prompted renal damage by activation of Nrf-2/Keap-1 ARE pathway in male mice
Iserhienrhien O. Lucky, Iyoha I. Aisuhuehien & Memudu E. Adejoke
Published online: 20 Mar 2024
  • 59 Views
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Research Article

Article
Subjective biosafety assessment of bisdemethoxycurcumin from the rhizomes of Curcuma longa
Muhammed Majeed, Sarang Bani, Anjali Pandey, Muhamad Ibrahim A.Smitha Thazhathidath
Published online: 13 Mar 2024
  • 35 Views
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Research Article

Article
Leflunomide-induced cardiac injury in adult male mice and bioinformatic approach identifying Nrf2/NF-κb signaling interplay
Abeer A. Rahman, Ann Hegazy, Lamiaa M. Elabbasy, Mohamed Z. Shoaeir, Tarek M. Abdel-Aziz, Awad S. Abbas, Heba W. Z. Khella, Amira H. Eltrawy, Reem Alshaman, Sheka Yagub Aloyouni, Afaf A. Aldahish & Sawsan A. Zaitone
Published online: 11 Mar 2024
  • 73 Views
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Research Article

Article
Mass spectrometric methods for evaluation of voriconazole avian pharmacokinetics and the inhibition of its cytochrome P450-induced metabolism
Andreas F. Lehner, Sharmie D. Johnson, Levent Dirikolu, Margaret Johnson & John P. Buchweitz
Published online: 29 Feb 2024
  • 33 Views
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Research Article

Article
Analyzing the impact of synthetic and natural steroids: a study of cytochrome P450 metabolism, morphological alterations through metabolomics, and histopathological Examination
Esat Mahmut Kocaman, Onur Şenol, Serkan Yıldırım, Muhammed Atamanalp, Sinan Özcan, İsmail Bolat, Arzu Ucar, Metin Kiliçlioğlu, Veysel Parlak, Mehmet Takkac & Gonca Alak
Published online: 27 Feb 2024
  • 95 Views
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Review Article

Review Article
Application of the threshold of toxicological concern (TTC) in the evaluation of drinking water contact chemicals
Kelly A. Magurany, J. Caroline English & Kevin D. Cox
Published online: 29 Nov 2023
  • 82 Views
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Review Article

Review Article
Third party product certification for drinking water health effects
Kathryn Foster & Kristin Licko
Published online: 30 May 2023
  • 78 Views
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