Xenobiotica, Volume 16, Issue 5 (1986)

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Xenobiotica, Volume 16, Issue 5 (1986)

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Editorial

Editorial
Editorial
Dennis V. Parke
Pages: 359-360
Published online: 22 Sep 2008
CitationforEditorial | PDF (101.5 KB)
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Research Article

Article
Introduction
R. L. Smith
Pages: 361-365
Published online: 22 Sep 2008
First Page PreviewforIntroduction | References | PDF (365.7 KB)
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Article
Human-liver cytochromes P-450 involved in polymorphisms of drug oxidation
F. P. Guengerich, L. M. Distlerath, P. E. B. Reilly, T. Wolff, T. Shimada, D. R. Umbenhauer & M. V. Martin
Pages: 367-378
Published online: 22 Sep 2008
AbstractforHuman-liver cytochromes P-450 involved in polymorphisms of drug oxidation | References | PDF (896.2 KB)
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Article
The genetic defect of mephenytoin hydroxylation
W. Kalow
Pages: 379-389
Published online: 22 Sep 2008
AbstractforThe genetic defect of mephenytoin hydroxylation | References | PDF (643.3 KB)
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Article
Oxidation of tricyclic antidepressant drugs, debrisoquine and 7-ethoxyresorufin, by human liver preparations
C. von Bahr, C. Birgersson, E. T. Morgan, Ö. Eriksson, M. Göransson, E. Spina & K. Woodhouse
Pages: 391-400
Published online: 22 Sep 2008
AbstractforOxidation of tricyclic antidepressant drugs, debrisoquine and 7-ethoxyresorufin, by human liver preparations | References | PDF (501.1 KB)
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Article
Polymorphisms of antipyrine and theophylline metabolism in man: Molecular and clinical implications
Elliot S. Vesell
Pages: 401-420
Published online: 22 Sep 2008
AbstractforPolymorphisms of antipyrine and theophylline metabolism in man: Molecular and clinical implications | References | PDF (1.3 MB)
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Article
Pharmacogenetics of dextromethorphan O-demethylation in man
A. Küpfer, B. Schmid & G. Pfaff
Pages: 421-433
Published online: 22 Sep 2008
AbstractforPharmacogenetics of dextromethorphan O-demethylation in man | References | PDF (691 KB)
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Article
Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol
M. S. Lennard, G. T. Tucker, J. H. Silas & H. F. Woods
Pages: 435-447
Published online: 22 Sep 2008
AbstractforDebrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol | References | PDF (596.9 KB)
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Article
The molecular mechanisms of two common polymorphisms of drug oxidation-evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation
U. A. Meyer, J. Gut, T. Kronbach, C. Skoda, U. T. Meier, T. Catin & P. Dayer
Pages: 449-464
Published online: 22 Sep 2008
AbstractforThe molecular mechanisms of two common polymorphisms of drug oxidation-evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation | References | PDF (888.9 KB)
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Article
The genetic polymorphism of sparteine metabolism
M. Eichelbaum, K.-P. Reetz, E. K. Schmidt & C. Zekorn
Pages: 465-481
Published online: 22 Sep 2008
AbstractforThe genetic polymorphism of sparteine metabolism | References | PDF (951.4 KB)
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Article
Oxidative metabolism of encainide: Polymorphism, pharmacokinetics and clinical considerations
C. B. McAllister, H. T. Wolfenden, W. S. Aslanian, R. L. Woosley & G. R. Wilkinson
Pages: 483-490
Published online: 22 Sep 2008
AbstractforOxidative metabolism of encainide: Polymorphism, pharmacokinetics and clinical considerations | References | PDF (476 KB)
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Article
Stereoselective pharmacokinetics of perhexiline
B. J. Gould, A. G. B. Amoah & D. V. Parke
Pages: 491-502
Published online: 22 Sep 2008
AbstractforStereoselective pharmacokinetics of perhexiline | References | PDF (632.1 KB)
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Article
The metabolism of debrisoquine in man: (1) Regioselectivity of hydroxylation and (2) aberrant oxidative metabolism in two sibling patients with carbimazole-induced agranulocytosis
J. C. Ritchie, M. J. Crothers, R. R. Shah, J. R. Idle & R. L. Smith
Pages: 503-509
Published online: 22 Sep 2008
AbstractforThe metabolism of debrisoquine in man: (1) Regioselectivity of hydroxylation and (2) aberrant oxidative metabolism in two sibling patients with carbimazole-induced agranulocytosis | References | PDF (358 KB)
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