Xenobiotica, Volume 18, Issue 12 (1988)

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Xenobiotica, Volume 18, Issue 12 (1988)

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Original Article

Article
The Metabolism and Disposition of 14C-Indolidan, a Potent and Orally Active Cardiotonic Agent, in Four Species of Laboratory Animals
J. R. Bernstein & R. B. Franklin
Pages: 1335-1345
Published online: 30 Sep 2009
AbstractforThe Metabolism and Disposition of 14C-Indolidan, a Potent and Orally Active Cardiotonic Agent, in Four Species of Laboratory Animals | References | PDF (602.9 KB)
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Article
A Novel Biologically Active Selenoorganic Compound. VIII. Biotransformation of Ebselen
Hartmut Fischer, Rolf Terlinden, Josef P. LÖhr & Axel RÖmer
Pages: 1347-1359
Published online: 30 Sep 2009
AbstractforA Novel Biologically Active Selenoorganic Compound. VIII. Biotransformation of Ebselen | References | PDF (641.9 KB)
  • 122 Views
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Article
Species Variation and Stereoselectivity in the Metabolism of Nicotine Enantiomers
C. G. Nwosu & P. A. Crooks
Pages: 1361-1372
Published online: 30 Sep 2009
AbstractforSpecies Variation and Stereoselectivity in the Metabolism of Nicotine Enantiomers | References | PDF (690.1 KB)
  • 86 Views
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Article
The Metabolism of 5-(4-Acetamidophenyl)Pyrazin-2(1H)-One in Rat, Dog and Cynomolgus Monkey
D. A. Ross, P. M. Osborne, M. A. Pue, T. J. Blake, R. J. Chenery & R. Metcalf
Pages: 1373-1387
Published online: 30 Sep 2009
AbstractforThe Metabolism of 5-(4-Acetamidophenyl)Pyrazin-2(1H)-One in Rat, Dog and Cynomolgus Monkey | References | PDF (2.5 MB)
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Article
Is the Nephrotoxicity of (R)-3-Chlorolactate in the Rat Caused by 3-Chloropyruvate?
M. S. Dobbie, K. E. Porter & A. R. Jones
Pages: 1389-1399
Published online: 30 Sep 2009
AbstractforIs the Nephrotoxicity of (R)-3-Chlorolactate in the Rat Caused by 3-Chloropyruvate? | References | PDF (747.1 KB)
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Article
The Metabolism of Propranolol (ICI 45, 520, InderalTm) and Xamoterol (ICI 118,587, CorwinTm) by Isolated Rat Hepatocytes: in Vivo-in Vitro Correlations
D. J. McCormick, T. C. Fitzgerald & D. McKillop
Pages: 1401-1412
Published online: 30 Sep 2009
AbstractforThe Metabolism of Propranolol (ICI 45, 520, InderalTm) and Xamoterol (ICI 118,587, CorwinTm) by Isolated Rat Hepatocytes: in Vivo-in Vitro Correlations | References | PDF (584.5 KB)
  • 54 Views
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Article
Disposition of bemitradine, a Renal Vasodilator and Diuretic, in Man
C. M. Walls, A. Gray, C. W. Vose, Y. Robinson, N. Lopez, R. D. Brownsill & J. A. Steiner
Pages: 1413-1423
Published online: 30 Sep 2009
AbstractforDisposition of bemitradine, a Renal Vasodilator and Diuretic, in Man | References | PDF (617 KB)
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Article
Microbial Models of Mammalian Metabolism: Production of Novel α-diketone Metabolites of Warfarin and Phenprocoumon Using Aspergillus Niger
Jinee D. Rizzo & P. J. Davis
Pages: 1425-1437
Published online: 30 Sep 2009
AbstractforMicrobial Models of Mammalian Metabolism: Production of Novel α-diketone Metabolites of Warfarin and Phenprocoumon Using Aspergillus Niger | References | PDF (839.6 KB)
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Article
The Metabolism of Chlorpromazine N-Oxide in the Rat
T. J. Jaworski, E. M. Hawes, G. McKay & K. K. Midha
Pages: 1439-1447
Published online: 30 Sep 2009
AbstractforThe Metabolism of Chlorpromazine N-Oxide in the Rat | References | PDF (528.3 KB)
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Article
Pharmacokinetics of Diclofenac and Five Metabolites After Single Doses in Healthy Volunteers and After Repeated Doses in Patients
Peter H. Degen, Walter Dieterle, Werner Schneider, Walter Theobald & Ursula Sinterhauf
Pages: 1449-1455
Published online: 30 Sep 2009
AbstractforPharmacokinetics of Diclofenac and Five Metabolites After Single Doses in Healthy Volunteers and After Repeated Doses in Patients | References | PDF (350.7 KB)
  • 174 Views
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Article
Interaction of 1,1,1-Trichloroethane with the Mixed-Function Oxidation System in Rat Liver Microsomes
Takehito Takano, Yoshifumi Miyazaki & Ryuichiro Araki
Pages: 1457-1464
Published online: 30 Sep 2009
AbstractforInteraction of 1,1,1-Trichloroethane with the Mixed-Function Oxidation System in Rat Liver Microsomes | References | PDF (424.9 KB)
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Article
Elimination and Accumulation of the Rodenticide Flocoumafen in Rats Following Repeated Oral Administration
K. R. Huckle, D. H. Hutson & P. A. Warburton
Pages: 1465-1479
Published online: 30 Sep 2009
AbstractforElimination and Accumulation of the Rodenticide Flocoumafen in Rats Following Repeated Oral Administration | References | PDF (794 KB)
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Article
Randomly Distributed DNA Single Strand Breaks are not Lethal for Mammalian Cells
O. Cantoni, P. Sestili & F. Cattabeni
Pages: 1481-1487
Published online: 30 Sep 2009
AbstractforRandomly Distributed DNA Single Strand Breaks are not Lethal for Mammalian Cells | References | PDF (348.2 KB)
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