Xenobiotica, Volume 21, Issue 11 (1991)

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Xenobiotica, Volume 21, Issue 11 (1991)

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Research Article

Article
Verofylline pharmacokinetics in dietary-induced obese rats: Role of fat mass and protein binding in determining volume of distribution
L. Shum & W. J. Jusko
Pages: 1419-1430
Published online: 22 Sep 2008
AbstractforVerofylline pharmacokinetics in dietary-induced obese rats: Role of fat mass and protein binding in determining volume of distribution | References | PDF (711.1 KB)
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Article
Investigations on the biotransformation of mebendazole using an isolated perfused rat gut system
H. Gottmanns, R. Kroker & F. R. Ungemach
Pages: 1431-1439
Published online: 22 Sep 2008
AbstractforInvestigations on the biotransformation of mebendazole using an isolated perfused rat gut system | References | PDF (601.3 KB)
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Article
Quinine is a more potent inhibitor than quinidine in rat of the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase
G. Muralidharan, E. M. Hawes, G. McKay & K. K. Midha
Pages: 1441-1450
Published online: 22 Sep 2008
AbstractforQuinine is a more potent inhibitor than quinidine in rat of the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase | References | PDF (707 KB)
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Article
The metabolites of chlorpromazine N-oxide in rat bile
T. J. Jaworski, E. M. Hawes, J. W. Hubbard, G. McKay & K. K. Midha
Pages: 1451-1459
Published online: 22 Sep 2008
AbstractforThe metabolites of chlorpromazine N-oxide in rat bile | References | PDF (528.8 KB)
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Article
Inhibition and induction of drug metabolism by psoralens: Alterations in duration of sleep induced by hexobarbital and in clearance of caffeine and hexobarbital in mice
G. Apseloff, J. B. Hilliard, N. Gerber & D. C. Mays
Pages: 1461-1471
Published online: 22 Sep 2008
AbstractforInhibition and induction of drug metabolism by psoralens: Alterations in duration of sleep induced by hexobarbital and in clearance of caffeine and hexobarbital in mice | References | PDF (742 KB)
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Article
The metabolism and excretion of prochloraz, an imidazole-based fungicide, in the rat
D. Needham & I. R. Challis
Pages: 1473-1482
Published online: 22 Sep 2008
AbstractforThe metabolism and excretion of prochloraz, an imidazole-based fungicide, in the rat | References | PDF (589.6 KB)
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Article
Species- and sex-related differences in the plasma clearance and metabolite formation of antipyrine. A comparative study in four animal species: Cattle, goat, rat and rabbit
R. F. Witkamp, J. A. C. M. Lohuis, S. M. Nijmeijer, H. J. Kolker, J. Noordhoek & A. S. J. P. A. M. Van Miert
Pages: 1483-1492
Published online: 22 Sep 2008
AbstractforSpecies- and sex-related differences in the plasma clearance and metabolite formation of antipyrine. A comparative study in four animal species: Cattle, goat, rat and rabbit | References | PDF (710.6 KB)
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Article
Identification of novel phencyclidine metabolites formed in vitro by rabbit microsomal metabolism
R. Herber, R. Perrin, J.-M. Ziegler, J. Villoutreix, A. Minn & G. Siest
Pages: 1493-1499
Published online: 22 Sep 2008
AbstractforIdentification of novel phencyclidine metabolites formed in vitro by rabbit microsomal metabolism | References | PDF (405 KB)
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Article
Thebaine O-demethylation to oripavine: Genetic differences between two rat strains
G. Mikus, A. A. Somogyi, F. Bochner & M. Eichelbaum
Pages: 1501-1509
Published online: 22 Sep 2008
AbstractforThebaine O-demethylation to oripavine: Genetic differences between two rat strains | References | PDF (536.2 KB)
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Article
Comparative pharmacokinetics and bioavailability of oxolinic acid and oxytetracycline in rainbow trout (Oncorhynchus mykiss)
H. V. Björklund & G. Bylund
Pages: 1511-1520
Published online: 22 Sep 2008
AbstractforComparative pharmacokinetics and bioavailability of oxolinic acid and oxytetracycline in rainbow trout (Oncorhynchus mykiss) | References | PDF (607.7 KB)
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Article
Identification of a hydroxy metabolite of diflunisal in rat and human urine
J. I. Macdonald, R. G. Dickinson, R. S. Reid, R. W. Edom, A. R. King & R. K. Verbeeck
Pages: 1521-1533
Published online: 22 Sep 2008
AbstractforIdentification of a hydroxy metabolite of diflunisal in rat and human urine | References | PDF (735.4 KB)
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Article
Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat
R. G. Dickinson, R. K. Verbeeck & A. R. King
Pages: 1535-1546
Published online: 22 Sep 2008
AbstractforAbsence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat | References | PDF (780.7 KB)
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