Xenobiotica, Volume 29, Issue 3 (1999)

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Xenobiotica, Volume 29, Issue 3 (1999)

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Research Article

Article
Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes
T. SHIRAGA, H. KANEKO, K. IWASAKI, Z. TOZUKA, A. SUZUKI & T. HATA
Pages: 217-229
Published online: 22 Sep 2008
AbstractforIdentification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes | References | PDF (253 KB)
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Article
Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes
H. YAMAZAKI
Pages: 231-241
Published online: 22 Sep 2008
AbstractforEffects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes | References | PDF (257.1 KB)
  • 266 Views
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Article
Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21
AKIO NAKAMURA
Pages: 243-252
Published online: 22 Sep 2008
AbstractforCytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21 | References | PDF (185.8 KB)
  • 57 Views
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Article
Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man
M. K. BAYLISS
Pages: 253-268
Published online: 22 Sep 2008
AbstractforUtility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man | References | PDF (269.7 KB)
  • 212 Views
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Article
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro
M. S. OGG
Pages: 269-279
Published online: 22 Sep 2008
AbstractforA reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro | References | PDF (262 KB)
  • 170 Views
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Article
Metabolism and degradation products of recombinant human insulin-like growth factor-I in lysosomes of rat kidney
Y. TANAKA
Pages: 281-295
Published online: 22 Sep 2008
AbstractforMetabolism and degradation products of recombinant human insulin-like growth factor-I in lysosomes of rat kidney | References | PDF (340.2 KB)
  • 19 Views
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Article
Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man
D. K. WALKER
Pages: 297-310
Published online: 22 Sep 2008
AbstractforPharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man | References | PDF (288.8 KB)
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Article
Disposition of ropinirole in animals and man
J. V. RAMJI
Pages: 311-325
Published online: 22 Sep 2008
AbstractforDisposition of ropinirole in animals and man | References | PDF (232.3 KB)
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