Xenobiotica, Volume 34, Issue 11-12 (2004)

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Xenobiotica, Volume 34, Issue 11-12 (2004)

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Research Article

Article
Expression of basolateral and canalicular transporters in rat liver and cultures of primary hepatocytes
J. Borlak & T. Klutcka
Pages: 935-947
Published online: 22 Sep 2008
AbstractforExpression of basolateral and canalicular transporters in rat liver and cultures of primary hepatocytes | References | PDF (414.9 KB)
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Article
Use of a cocktail of probe substrates for drug-metabolizing enzymes for the assessment of the metabolic capacity of hepatocyte preparations
E. Floby, S. Briem, Y. Terelius & A.-K. Sohlenius-Sternbeck
Pages: 949-959
Published online: 22 Sep 2008
AbstractforUse of a cocktail of probe substrates for drug-metabolizing enzymes for the assessment of the metabolic capacity of hepatocyte preparations | References | PDF (121.7 KB)
  • 275 Views
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Article
Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors
H. Fujino, T. Saito, Y. Tsunenari, J. Kojima & T. Sakaeda
Pages: 961-971
Published online: 22 Sep 2008
AbstractforMetabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors | References | PDF (367 KB)
  • 592 Views
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Article
Role of human cytochrome P450 3A4 in the metabolism of DA–8159, a new erectogenic
H. Y. Ji, H. W. Lee, H. H. Kim, D. S. Kim, M. Yoo, W. B. Kim & H. S. Lee
Pages: 973-982
Published online: 22 Sep 2008
AbstractforRole of human cytochrome P450 3A4 in the metabolism of DA–8159, a new erectogenic | References | PDF (135.2 KB)
  • 100 Views
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Article
In vitro metabolism of gefitinib in human liver microsomes
D. Mckillop, A. D. Mccormick, G. S. Miles, P. J. Phillips, K. J. Pickup, N. Bushby & M. Hutchison
Pages: 983-1000
Published online: 22 Sep 2008
AbstractforIn vitro metabolism of gefitinib in human liver microsomes | References | PDF (211.6 KB)
  • 377 Views
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Article
In vitro metabolism of quazepam in human liver and intestine and assessment of drug interactions
M. Miura & T. Ohkubo
Pages: 1001-1011
Published online: 22 Sep 2008
AbstractforIn vitro metabolism of quazepam in human liver and intestine and assessment of drug interactions | References | PDF (122.2 KB)
  • 152 Views
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Article
Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone
C. Simard, V. Michaud, B. Gibbs, R. Massé, É Lessard & J. Turgeon
Pages: 1013-1023
Published online: 22 Sep 2008
AbstractforIdentification of the cytochrome P450 enzymes involved in the metabolism of domperidone | References | PDF (156 KB)
  • 156 Views
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Article
Incorporation of xenobiotic carboxylic acids into lipids by cultured 3T3-L1 adipocytes
S. Vickery & P. F. Dodds
Pages: 1025-1042
Published online: 22 Sep 2008
AbstractforIncorporation of xenobiotic carboxylic acids into lipids by cultured 3T3-L1 adipocytes | References | PDF (373 KB)
  • 58 Views
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Article
Triclabendazole biotransformation and comparative diffusion of the parent drug and its oxidized metabolites into Fasciola hepatica
L. Mottier, G. Virkel, H. Solana, L. Alvarez, J. Salles & C. Lanusse
Pages: 1043-1057
Published online: 22 Sep 2008
AbstractforTriclabendazole biotransformation and comparative diffusion of the parent drug and its oxidized metabolites into Fasciola hepatica | References | PDF (165.1 KB)
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Article
Renal elimination of a novel and potent αvβ3 integrin antagonist in animals
T. Prueksaritanont, J. H. Hochman, Y. Meng, N. T. Pudvah, A. Barrish, B. Ma, M. Yamazaki, C. Fernandez-metzler & J. H. Lin
Pages: 1059-1074
Published online: 22 Sep 2008
AbstractforRenal elimination of a novel and potent αvβ3 integrin antagonist in animals | References | PDF (290.2 KB)
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Article
Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism
E. Skordi, I. D. Wilson, J. C. Lindon & J. K. Nicholson
Pages: 1075-1089
Published online: 22 Sep 2008
AbstractforCharacterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism | References | PDF (373.1 KB)
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