Xenobiotica, Volume 34, Issue 1 (2004)

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Xenobiotica, Volume 34, Issue 1 (2004)

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Original Article

Article
Effects of renal diseases on the regulation and expression of renal and hepatic drug-metabolizing enzymes: a review
H. M. Korashy, R. H. Elbekai & A. O. S. El-Kadi
Pages: 1-29
Published online: 12 Jul 2010
AbstractforEffects of renal diseases on the regulation and expression of renal and hepatic drug-metabolizing enzymes: a review | References | PDF (262.1 KB)
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Article
Comparison of the metabolism of ethylene glycol and glycolic acid in vitro by precision-cut tissue slices from female rat, rabbit and human liver
E. D. Booth, O. Dofferhoff, P. J. Boogaard & W. P. Watson
Pages: 31-48
Published online: 12 Jul 2010
AbstractforComparison of the metabolism of ethylene glycol and glycolic acid in vitro by precision-cut tissue slices from female rat, rabbit and human liver | References | PDF (283.6 KB)
  • 134 Views
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Article
Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9
S. L. Boye, O. Kerdpin, D. J. Elliot, J. O. Miners, L. Kelly, R. A. Mckinnon, C. R. Bhasker, K. Yoovathaworn & D. J. Birkett
Pages: 49-60
Published online: 12 Jul 2010
AbstractforOptimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9 | References | PDF (178.1 KB)
  • 125 Views
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Article
Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes
K. Umehara, Y. Shimokawa, T. Koga, T. Ohtani & G. Miyamoto
Pages: 61-71
Published online: 12 Jul 2010
AbstractforOxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes | References | PDF (177.8 KB)
  • 58 Views
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Article
NMR and QSAR studies on the transacylation reactivity of model 1β-O-acyl glucuronides. I: design, synthesis and degradation rate measurement
S. J. Vanderhoeven, J. C. Lindon, J. Troke, G. E. Tranter, I. D. Wilson & J. K. Nicholson
Pages: 73-85
Published online: 02 Oct 2013
AbstractforNMR and QSAR studies on the transacylation reactivity of model 1β-O-acyl glucuronides. I: design, synthesis and degradation rate measurement | References | PDF (1.9 MB)
  • 69 Views
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Article
High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method
T. Yamamoto, A. Suzuki & Y. Kohno
Pages: 87-101
Published online: 12 Jul 2010
AbstractforHigh-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method | References | PDF (319.8 KB)
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Research Article

Article
Disposition of a novel and potent αvβ3 antagonist in animals, and extrapolation to man
T. Prueksaritanont, C. Fernandez-Metzler, Y. Meng, A. Barrish, W. Halczenko, S. B. Rodan, J. H. Hutchinson, M. E. Duggan & J. H. Lin
Pages: 103-115
Published online: 22 Sep 2008
AbstractforDisposition of a novel and potent αvβ3 antagonist in animals, and extrapolation to man | References | PDF (176.4 KB)
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