Xenobiotica, Volume 35, Issue 3 (2005)

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Xenobiotica, Volume 35, Issue 3 (2005)

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Research Article

Article
In vitro metabolism of an orally active O-methyl amidoxime prodrug for the treatment of CNS trypanosomiasis
J. H Ansede, R. D Voyksner, M. A Ismail, D. W Boykin, R. R Tidwell & J. E Hall
Pages: 211-226
Published online: 22 Sep 2008
AbstractforIn vitro metabolism of an orally active O-methyl amidoxime prodrug for the treatment of CNS trypanosomiasis | References | PDF (195.1 KB)
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Article
Identification of cytochrome P450 enzymes involved in the metabolism of 3′,4′-methylenedioxy-α-pyrrolidinopropiophenone (MDPPP), a designer drug, in human liver microsomes
D Springer, R. F Staack, L. D Paul, T Kraemer & H. H Maurer
Pages: 227-237
Published online: 22 Sep 2008
AbstractforIdentification of cytochrome P450 enzymes involved in the metabolism of 3′,4′-methylenedioxy-α-pyrrolidinopropiophenone (MDPPP), a designer drug, in human liver microsomes | References | PDF (218.1 KB)
  • 131 Views
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Article
Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat
H Xie, P Afsharian, Y Terelius, R. A Mirghani, Ü Yasar, A-L Hagbjörk, S Lundgren, Y Hu, A Rane & M Hassan
Pages: 239-251
Published online: 22 Sep 2008
AbstractforCyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat | References | PDF (134.2 KB)
  • 91 Views
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Article
Pre-clinical assessment of DRF 4367, a novel COX-2 inhibitor: Evaluation of pharmacokinetics, absolute oral bioavailability and metabolism in mice and comparative inter-species in vitro metabolism
R Bhamidipati, S Mujeeb, P. V Dravid, A. A Khan, S. K Singh, Y. K Rao, R Mullangi & N. R Srinivas
Pages: 253-271
Published online: 22 Sep 2008
AbstractforPre-clinical assessment of DRF 4367, a novel COX-2 inhibitor: Evaluation of pharmacokinetics, absolute oral bioavailability and metabolism in mice and comparative inter-species in vitro metabolism | References | PDF (286.7 KB)
  • 60 Views
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Article
Absorption, distribution, metabolism and excretion of an inhalation dose of [14C] 4,4'-methylenediphenyl diisocyanate in the male rat
A Gledhill, A Wake, P Hext, E Leibold & R Shiotsuka
Pages: 273-292
Published online: 22 Sep 2008
AbstractforAbsorption, distribution, metabolism and excretion of an inhalation dose of [14C] 4,4'-methylenediphenyl diisocyanate in the male rat | References | PDF (198.1 KB)
  • 86 Views
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Article
In vitro metabolism and in vivo pharmacokinetics of quinoline 3-carboxamide derivatives in various species
H Tuvesson, I Hallin, M Ellman, B Sparre, P. O Gunnarsson & J Seidegård
Pages: 293-304
Published online: 22 Sep 2008
AbstractforIn vitro metabolism and in vivo pharmacokinetics of quinoline 3-carboxamide derivatives in various species | References | PDF (148.6 KB)
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