Xenobiotica, Volume 35, Issue 4 (2005)

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Xenobiotica, Volume 35, Issue 4 (2005)

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Research Article

Article
Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug–drug interaction model rats
Takushi Kanazu, Noboru Okamura, Yoshitaka Yamaguchi, Takahiko Baba & Masahiro Koike
Pages: 305-317
Published online: 22 Sep 2008
AbstractforAssessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug–drug interaction model rats | References | PDF (249.4 KB)
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Article
In vitro metabolism of 2,2′,3,4′,5,5′,6-heptachlorobiphenyl (CB187) by liver microsomes from rats, hamsters and guinea pigs
C. Ohta, K. Haraguchi, Y. Kato & N. Koga
Pages: 319-330
Published online: 22 Sep 2008
AbstractforIn vitro metabolism of 2,2′,3,4′,5,5′,6-heptachlorobiphenyl (CB187) by liver microsomes from rats, hamsters and guinea pigs | References | PDF (133.8 KB)
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Article
Comparative in vitro metabolism of the suspected pro-oestrogenic compound, methoxychlor in precision-cut liver slices from male and female rats
K. Ohyama, S. Maki, K. Sato & Y. Kato
Pages: 331-342
Published online: 22 Sep 2008
AbstractforComparative in vitro metabolism of the suspected pro-oestrogenic compound, methoxychlor in precision-cut liver slices from male and female rats | References | PDF (128 KB)
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Article
Structural identification of bitespiramycin metabolites in rat: A single oral dose study
X. G. Shi, J. P. Fawcett, X. Y. Chen & D. F. Zhong
Pages: 343-358
Published online: 22 Sep 2008
AbstractforStructural identification of bitespiramycin metabolites in rat: A single oral dose study | References | PDF (399.2 KB)
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Article
Identification of metabolites of [14C]zonampanel, an α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, following intravenous infusion in healthy volunteers
T. Minematsu, K.-Y. Sohda, T. Hashimoto, H. Imai, T. Usui & H. Kamimura
Pages: 359-371
Published online: 22 Sep 2008
AbstractforIdentification of metabolites of [14C]zonampanel, an α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, following intravenous infusion in healthy volunteers | References | PDF (142.8 KB)
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Article
Pharmacokinetics and metabolism of TR-14035, a novel antagonist of α4β1/α4β7 integrin mediated cell adhesion, in rat and dog
M. Tsuda-Tsukimoto, Y. Ogasawara & T. Kume
Pages: 373-389
Published online: 22 Sep 2008
AbstractforPharmacokinetics and metabolism of TR-14035, a novel antagonist of α4β1/α4β7 integrin mediated cell adhesion, in rat and dog | References | PDF (475.6 KB)
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Article
Uptake–toxicity relationships of a series of N-substituted N′-(4-imidazole-ethyl)thiourea in precision-cut rat liver slices
R. C. A. Onderwater, J. N. M. Commandeur, M. Rooseboom & N. P. E. Vermeulen
Pages: 391-404
Published online: 16 Oct 2008
AbstractforUptake–toxicity relationships of a series of N-substituted N′-(4-imidazole-ethyl)thiourea in precision-cut rat liver slices | References | PDF (133.1 KB)
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