Xenobiotica, Volume 35, Issue 6 (2005)

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Xenobiotica, Volume 35, Issue 6 (2005)

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Research Article

Article
Growth and hepatic in vitro metabolism of ergotamine in mice divergently selected for response to endophyte toxicity
J. M. Duringer, R. Lewis, L. Kuehn, T. Fleischmann & A. M. Craig
Pages: 531-548
Published online: 22 Sep 2008
AbstractforGrowth and hepatic in vitro metabolism of ergotamine in mice divergently selected for response to endophyte toxicity | References | PDF (199 KB)
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Article
Inhibitory effects of psychotropic drugs on mexiletine metabolism in human liver microsomes: Prediction of in vivo drug interactions
Y. Hara, M. Nakajima, K.-I. Miyamoto & T. Yokoi
Pages: 549-560
Published online: 22 Sep 2008
AbstractforInhibitory effects of psychotropic drugs on mexiletine metabolism in human liver microsomes: Prediction of in vivo drug interactions | References | PDF (492 KB)
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Article
Stereospecific oxidation of the (S)-enantiomer of RS-8359, a selective and reversible monoamine oxidase A (MAO-A) inhibitor, by aldehyde oxidase
K. Itoh, M. Yamamura, S. Muramatsu, K. Hoshino, A. Masubuchi, T. Sasaki & Y. Tanaka
Pages: 561-573
Published online: 22 Sep 2008
AbstractforStereospecific oxidation of the (S)-enantiomer of RS-8359, a selective and reversible monoamine oxidase A (MAO-A) inhibitor, by aldehyde oxidase | References | PDF (293.1 KB)
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Article
Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates
H. Komura & M. Iwaki
Pages: 575-587
Published online: 22 Sep 2008
AbstractforUsefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates | References | PDF (131.7 KB)
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Article
Identification of cytochrome P450 forms involved in the 4-hydroxylation of valsartan, a potent and specific angiotensin II receptor antagonist, in human liver microsomes
A. Nakashima, H. Kawashita, N. Masuda, C. Saxer, M. Niina, Y. Nagae & K. Iwasaki
Pages: 589-602
Published online: 22 Sep 2008
AbstractforIdentification of cytochrome P450 forms involved in the 4-hydroxylation of valsartan, a potent and specific angiotensin II receptor antagonist, in human liver microsomes | References | PDF (157.6 KB)
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Article
Microsomal prediction of in vivo clearance and associated interindividual variability of six benzodiazepines in humans
H. C. Rawden, D. J. Carlile, A. Tindall, D. Hallifax, A. Galetin, K. Ito & J. B. Houston
Pages: 603-625
Published online: 22 Sep 2008
AbstractforMicrosomal prediction of in vivo clearance and associated interindividual variability of six benzodiazepines in humans | References | PDF (267.8 KB)
  • 216 Views
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Article
Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: Comparison among well-stirred, parallel-tube, distributed and dispersion models
T. Yamamoto, H. Itoga, Y. Kohno, K. Nagata & Y. Yamazoe
Pages: 627-646
Published online: 22 Sep 2008
AbstractforPrediction of oral clearance from in vitro metabolic data using recombinant CYPs: Comparison among well-stirred, parallel-tube, distributed and dispersion models | References | PDF (219.4 KB)
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Article
Metabolism and disposition of a β3-adrenergic receptor agonist LY368842 in male Fisher 344 rats
T. L. Abraham, T. J. Lindsay, S. H. Chay, B. A. Czeskis & M. M. He
Pages: 647-660
Published online: 22 Sep 2008
AbstractforMetabolism and disposition of a β3-adrenergic receptor agonist LY368842 in male Fisher 344 rats | References | PDF (171.4 KB)
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