Xenobiotica, Volume 36, Issue 4 (2006)

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Xenobiotica, Volume 36, Issue 4 (2006)

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Research Article

Article
Effect of natural analogues of trans-resveratrol on cytochromes P4501A2 and 2E1 catalytic activities
R. Mikstacka, A. M. Rimando, K. Szalaty, K. Stasik & W. Baer-Dubowska
Pages: 269-285
Published online: 22 Sep 2008
AbstractforEffect of natural analogues of trans-resveratrol on cytochromes P4501A2 and 2E1 catalytic activities | Full Text | References | PDF (132.7 KB)
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Article
Comparative analysis of substrate and inhibitor interactions with CYP3A4 and CYP3A5
M. G. Soars, K. Grime & R. J. Riley
Pages: 287-299
Published online: 22 Sep 2008
AbstractforComparative analysis of substrate and inhibitor interactions with CYP3A4 and CYP3A5 | Full Text | References | PDF (108.2 KB)
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Article
Species differences in hydrolase activities toward OT-7100 responsible for different bioavailability in rats, dogs, monkeys and humans
S. Kuribayashi, N. Ueda, S. Naito, H. Yamazaki & T. Kamataki
Pages: 301-314
Published online: 22 Sep 2008
AbstractforSpecies differences in hydrolase activities toward OT-7100 responsible for different bioavailability in rats, dogs, monkeys and humans | Full Text | References | PDF (135.5 KB)
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Article
Aldehyde oxidase and its contribution to the metabolism of a structurally novel, functionally selective GABAA α5-subtype inverse agonist
D. O’Connor, P. Jones, M. S. Chambers, R. Maxey, H. J. Szekeres, N. Szeto, P. Scott-Stevens, A. M. Macleod, M. Braun & B. Cato
Pages: 315-330
Published online: 22 Sep 2008
AbstractforAldehyde oxidase and its contribution to the metabolism of a structurally novel, functionally selective GABAA α5-subtype inverse agonist | Full Text | References | PDF (168.9 KB)
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Article
Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans
S. Sakuda, T. Akabane & T. Teramura
Pages: 331-340
Published online: 22 Sep 2008
AbstractforMarked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans | Full Text | References | PDF (96.9 KB)
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Article
Pharmacokinetics and clearance processes of UK-279,276 (rNIF) in rat and dog: Comparison with human data
R. Webster, A. Edgington, J. Phipps & D. Walker
Pages: 341-349
Published online: 22 Sep 2008
AbstractforPharmacokinetics and clearance processes of UK-279,276 (rNIF) in rat and dog: Comparison with human data | Full Text | References | PDF (95.1 KB)
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