Xenobiotica, Volume 38, Issue 12 (2008)

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Xenobiotica, Volume 38, Issue 12 (2008)

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Original Article

Article
Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2
A. Messina, V. Chirulli, P. G. Gervasi & V. Longo
Pages: 1453-1470
Published online: 21 Nov 2008
AbstractforPurification, molecular cloning, heterologous expression and characterization of pig CYP1A2 | Full Text | References | PDF (788.1 KB)
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Article
Increased distribution of carboplatin, an anti-cancer agent, to rat brains with the aid of hyperbaric oxygenation
Y. Suzuki, K. Tanaka, D. Neghishi, M. Shimizu, N. Murayama, T. Hashimoto & H. Yamazaki
Pages: 1471-1475
Published online: 21 Nov 2008
AbstractforIncreased distribution of carboplatin, an anti-cancer agent, to rat brains with the aid of hyperbaric oxygenation | Full Text | References | PDF (71.3 KB)
  • 50 Views
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Article
In vivo metabolism of α-methyltryptamine in rats: Identification of urinary metabolites
T. Kanamori, K. Kuwayama, K. Tsujikawa, H. Miyaguchi, Y. T. Iwata & H. Inoue
Pages: 1476-1486
Published online: 21 Nov 2008
AbstractforIn vivo metabolism of α-methyltryptamine in rats: Identification of urinary metabolites | Full Text | References | PDF (461.8 KB)
  • 164 Views
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Article
Expression of a skin cholesterol sulfotransferase, St2b2, is a trigger of epidermal cell differentiation
M. Shimada, T. Matsuda, A. Sato, T. Akase, T. Matsubara, K. Nagata & Y. Yamazoe
Pages: 1487-1499
Published online: 21 Nov 2008
AbstractforExpression of a skin cholesterol sulfotransferase, St2b2, is a trigger of epidermal cell differentiation | Full Text | References | PDF (722.4 KB)
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Article
Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies
J. R. Kenny, L. Chen, D. F. McGinnity, K. Grime, K. M. Shakesheff, B. Thomson & R. Riley
Pages: 1500-1517
Published online: 21 Nov 2008
AbstractforEfficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies | Full Text | References | PDF (308.7 KB)
  • 334 Views
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Article
Toward an improved prediction of human in vivo brain penetration
S. G. Summerfield, A. J. Lucas, R. A. Porter, P. Jeffrey, R. N. Gunn, K. R. Read, A. J. Stevens, A. C. Metcalf, M. C. Osuna, P. J. Kilford, J. Passchier & A. D. Ruffo
Pages: 1518-1535
Published online: 21 Nov 2008
AbstractforToward an improved prediction of human in vivo brain penetration | Full Text | References | PDF (122 KB)
  • 946 Views
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Article
Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models
J.-S. Taur & R. Rodriguez-Proteau
Pages: 1536-1550
Published online: 21 Nov 2008
AbstractforEffects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models | Full Text | References | PDF (120 KB)
  • 332 Views
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Article
Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes
W. Li, Y. Liu, Y.-Q. He, J.-W. Zhang, Y. Gao, G.-B. Ge, H.-X. Liu, H. Huo, H.-T. Liu, L.-M. Wang, J. Sun, Q. Wang & L. Yang
Pages: 1551-1565
Published online: 21 Nov 2008
AbstractforCharacterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes | Full Text | References | PDF (535.8 KB)
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