Xenobiotica, Volume 40, Issue 12 (2010)

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Xenobiotica, Volume 40, Issue 12 (2010)

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General Xenobiochemistry

Article
Prediction of clinical CYP3A4 induction using cryopreserved human hepatocytes
A. Kaneko, M. Kato, C. Endo, K. Nakano, M. Ishigai & K. Takeda
Pages: 791-799
Published online: 23 Sep 2010
AbstractforPrediction of clinical CYP3A4 induction using cryopreserved human hepatocytes | Full Text | References | PDF (778 KB)
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Article
Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes
Furong Qiu, Rong Zhang, Guangji Wang, Chenglu Gao, Jianguo Sun, Jian Jiang & Yueming Ma
Pages: 800-806
Published online: 22 Oct 2010
AbstractforActivation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes | Full Text | References | PDF (704.4 KB)
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Article
Inhibition and induction of human cytochrome P450 enzymes in vitro by capsaicin
Sunita Babbar, Sanjay Chanda & Keith Bley
Pages: 807-816
Published online: 23 Sep 2010
AbstractforInhibition and induction of human cytochrome P450 enzymes in vitro by capsaicin | Full Text | References | PDF (668.3 KB)
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Article
Sitagliptin attenuates metformin-mediated AMPK phosphorylation through inhibition of organic cation transporters
Min-Koo Choi, Qing-Ri Jin, Sung-Hoon Ahn, Myung-Ae Bae & Im-Sook Song
Pages: 817-825
Published online: 23 Sep 2010
AbstractforSitagliptin attenuates metformin-mediated AMPK phosphorylation through inhibition of organic cation transporters | Full Text | References | PDF (950.8 KB)
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Animal Pharmacokinetics and Metabolism

Article
The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3/4A protease
E. Monteagudo, M. Fonsi, X. Chu, K. Bleasby, R. Evers, V. Pucci, M.V. Orsale, S. Cianetti, M. Ferrara, S. Harper, R. Laufer, M. Rowley & V. Summa
Pages: 826-839
Published online: 07 Oct 2010
AbstractforThe metabolism and disposition of a potent inhibitor of hepatitis C virus NS3/4A protease | Full Text | References | PDF (1.1 MB)
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Article
Pharmacokinetics and metabolism of the dipeptidyl peptidase IV inhibitor carmegliptin in rats, dogs, and monkeys
Olaf Kuhlmann, Axel Paehler, Idelette Weick, Christoph Funk, Michael Pantze, Manfred Zell & Uwe Timm
Pages: 840-852
Published online: 24 Sep 2010
AbstractforPharmacokinetics and metabolism of the dipeptidyl peptidase IV inhibitor carmegliptin in rats, dogs, and monkeys | Full Text | References | PDF (903.1 KB)
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Pharmacogenetics

Article
Genetic polymorphisms of Glycine N-acyltransferase (GLYAT) in a French Caucasian population
Christian Lacks Lino Cardenas, Joanna Bourgine, Christelle Cauffiez, Delphine Allorge, Jean Marc Lo-Guidice, Frank Broly & Dany Chevalier
Pages: 853-861
Published online: 07 Oct 2010
AbstractforGenetic polymorphisms of Glycine N-acyltransferase (GLYAT) in a French Caucasian population | Full Text | References | PDF (1 MB)
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Acknowledgements

Acknowledgements
Pages: 862-863
Published online: 09 Nov 2010
CitationforAcknowledgements | Full Text | PDF (485.2 KB)
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