Xenobiotica, Volume 40, Issue 5 (2010)

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Xenobiotica, Volume 40, Issue 5 (2010)

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Commentary

Article Commentary
A physiological role for flavin-containing monooxygenase (FMO3) in humans?
S. C. Mitchell & R. L. Smith
Pages: 301-305
Published online: 15 Mar 2010
First Page PreviewforA physiological role for flavin-containing monooxygenase (FMO3) in humans? | Full Text | References | PDF (597.3 KB)
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General Xenobiochemistry

Article
Role for protein kinase C delta in the functional activity of human UGT1A6: implications for drug–drug interactions between PKC inhibitors and UGT1A6
L. P. Volak & M. H. Court
Pages: 306-318
Published online: 02 Mar 2010
AbstractforRole for protein kinase C delta in the functional activity of human UGT1A6: implications for drug–drug interactions between PKC inhibitors and UGT1A6 | Full Text | References | PDF (875.4 KB)
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Article
Post-translational activation of human phenylalanine 4-monooxygenase from an endobiotic to a xenobiotic enzyme by reactive oxygen and reactive nitrogen species
A. Antypa, C. Rebello, A. Biernacka, K. Krajewski, J. Cassam, S. C. Mitchell & G. B. Steventon
Pages: 319-330
Published online: 15 Mar 2010
AbstractforPost-translational activation of human phenylalanine 4-monooxygenase from an endobiotic to a xenobiotic enzyme by reactive oxygen and reactive nitrogen species | Full Text | References | PDF (846.4 KB)
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Article
IC50-based approaches as an alternative method for assessment of time-dependent inhibition of CYP3A4
Howard J. Burt, Aleksandra Galetin & J. Brian Houston
Pages: 331-343
Published online: 15 Mar 2010
AbstractforIC50-based approaches as an alternative method for assessment of time-dependent inhibition of CYP3A4 | Full Text | References | PDF (970.8 KB)
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Clinical Pharmacokinetics and Metabolism

Article
Pharmacokinetics of antofloxacin hydrochloride, a novel fluoroquinolone, after single-dose intravenous administration in healthy Chinese male volunteers
J. Wang, Y. Xiao, Y. Lu, Z. Kang, M. Zhang, Y. Liu, J. Liang, M. Zhang & T. Li
Pages: 344-349
Published online: 15 Mar 2010
AbstractforPharmacokinetics of antofloxacin hydrochloride, a novel fluoroquinolone, after single-dose intravenous administration in healthy Chinese male volunteers | Full Text | References | PDF (634.3 KB)
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Animal Pharmacokinetics and Metabolism

Article
Pharmacokinetic/pharmacodynamic modelling of 2-acetyl-4(5)-tetrahydroxybutyl imidazole-induced peripheral lymphocyte sequestration through increasing lymphoid sphingosine 1-phosphate
X. Q. Yu, J. Kramer, L. Moran, E. O’Neill, A. Nouraldeen, T. Oravecz & A. G. E. Wilson
Pages: 350-356
Published online: 22 Feb 2010
AbstractforPharmacokinetic/pharmacodynamic modelling of 2-acetyl-4(5)-tetrahydroxybutyl imidazole-induced peripheral lymphocyte sequestration through increasing lymphoid sphingosine 1-phosphate | Full Text | References | PDF (681.5 KB)
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Topics in Xenobiochemistry

Review Article
Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives
N. R. Srinivas
Pages: 357-367
Published online: 15 Mar 2010
AbstractforBaicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives | Full Text | References | PDF (686.4 KB)
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