Xenobiotica, Volume 40, Issue 9 (2010)

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Xenobiotica, Volume 40, Issue 9 (2010)

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General Xenobiochemistry

Article
In vitro oxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxide ex vivo
Hana Bártíková, Ivan Vokřál, Lenka Skálová, Jiří Lamka & Barbora Szotáková
Pages: 593-601
Published online: 19 Jun 2010
AbstractforIn vitro oxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxide ex vivo | Full Text | References | PDF (904.4 KB)
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Article
Intestinal absorption mechanisms of ginsenoside Rh2: stereoselectivity and involvement of ABC transporters
Y. Gu, G.-J. Wang, X.-L. Wu, Y.-T. Zheng, J.-W. Zhang, H. Ai, J.-G. Sun & Y.-W. Jia
Pages: 602-612
Published online: 07 Jul 2010
AbstractforIntestinal absorption mechanisms of ginsenoside Rh2: stereoselectivity and involvement of ABC transporters | Full Text | References | PDF (758.1 KB)
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Article
Time interval from cigarette smoke exposure to blood donation and markers of inflammation: should a smoking cut-off be designated?
Emmanouil K. Symvoulakis, Constantine I. Vardavas, Popi Fountouli, Aimilia Stavroulaki, Katerina M. Antoniou, George Duijker, Manolis N. Tzatzarakis, Katerina Sfiridaki, Eirini Bolonaki, Thanasis Alegakis & Aristidis M. Tsatsakis
Pages: 613-620
Published online: 05 Jul 2010
AbstractforTime interval from cigarette smoke exposure to blood donation and markers of inflammation: should a smoking cut-off be designated? | Full Text | References | PDF (613.4 KB)
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Article
A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin
Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki & Yasuhiro Uno
Pages: 621-629
Published online: 12 Aug 2010
AbstractforA novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin | Full Text | References | PDF (731.5 KB)
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Clinical Pharmacokinetics and Metabolism

Article
Influence of CYP2C19 and ABCB1 polymorphisms on plasma concentrations of lansoprazole enantiomers after enteral administration
Masatomo Miura, Satoru Motoyama, Yudai Hinai, Takenori Niioka, Masahiro Endo, Makoto Hayakari & Jun-ichi Ogawa
Pages: 630-636
Published online: 07 Jun 2010
AbstractforInfluence of CYP2C19 and ABCB1 polymorphisms on plasma concentrations of lansoprazole enantiomers after enteral administration | Full Text | References | PDF (629.8 KB)
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Article
Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds
A.-K. Sohlenius-Sternbeck, L. Afzelius, P. Prusis, J. Neelissen, J. Hoogstraate, J. Johansson, E. Floby, A. Bengtsson, O. Gissberg, J. Sternbeck & C. Petersson
Pages: 637-649
Published online: 12 Jul 2010
AbstractforEvaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds | Full Text | References | PDF (865.4 KB)
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Animal Pharmacokinetics and Metabolism

Article
In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys
V.B.G. Reddy, G.A. Doss, B.V. Karanam, K. Samuel, T.J. Lanza Jr, L.S. Lin, N.X. Yu, A.S. Zhang, C.E. Raab, R.A. Stearns & S. Kumar
Pages: 650-662
Published online: 07 Jul 2010
AbstractforIn vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys | Full Text | References | PDF (1 MB)
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