Xenobiotica, Volume 41, Issue 3 (2011)

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Xenobiotica, Volume 41, Issue 3 (2011)

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General Xenobiochemistry

Article
Microbial production of phase I and phase II metabolites of propranolol
Cyrille Marvalin & Robert Azerad
Pages: 175-186
Published online: 26 Nov 2010
AbstractforMicrobial production of phase I and phase II metabolites of propranolol | Full Text | References | PDF (976.7 KB)
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Article
Mechanisms of gender-specific regulation of mouse sulfotransferases (Sults)
Yazen Alnouti & Curtis D. Klaassen
Pages: 187-197
Published online: 23 Nov 2010
AbstractforMechanisms of gender-specific regulation of mouse sulfotransferases (Sults) | Full Text | References | PDF (869.2 KB)
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Animal Pharmacokinetics and Metabolism

Article
Identification of phase-I metabolites and chronic toxicity study of the Kv1.3 blocker PAP-1 (5-(4-phenoxybutoxy)psoralen) in the rat
B. Hao, Z.-W. Chen, X.-J. Zhou, P.I. Zimin, G.P. Miljanich, H. Wulff & Y.-X. Wang
Pages: 198-211
Published online: 11 Nov 2010
AbstractforIdentification of phase-I metabolites and chronic toxicity study of the Kv1.3 blocker PAP-1 (5-(4-phenoxybutoxy)psoralen) in the rat | Full Text | References | PDF (1 MB)
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Article
In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite
Silvio Aprile, Erika Del Grosso & Giorgio Grosa
Pages: 212-225
Published online: 18 Nov 2010
AbstractforIn vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite | Full Text | References | PDF (1,017.7 KB) | Supplemental
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Article
Pharmacokinetics of the prodrug thiamphenicol glycinate and its active parent compound thiamphenicol in beagle dogs following intravenous administration
Bing Yang, Yang Lu, Jianheng Zheng, Jing Zhu, Jiake He, Di Zhao, Pengfei Song & Xijing Chen
Pages: 226-231
Published online: 23 Nov 2010
AbstractforPharmacokinetics of the prodrug thiamphenicol glycinate and its active parent compound thiamphenicol in beagle dogs following intravenous administration | Full Text | References | PDF (693.1 KB)
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Article
In vitro metabolism of α7 neuronal nicotinic receptor agonist AZD0328 and enzyme identification for its N-oxide metabolite
Diansong Zhou, Minli Zhang, Xiaomei Ye, Chungang Gu, Timothy M. Piser, Bernard A. Lanoue, Sara A. Schock, Yi-Fang Cheng & Scott W. Grimm
Pages: 232-242
Published online: 13 Jan 2011
AbstractforIn vitro metabolism of α7 neuronal nicotinic receptor agonist AZD0328 and enzyme identification for its N-oxide metabolite | Full Text | References | PDF (921.2 KB)
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Article
Pharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol
In-Soo Yoon, Min-Koo Choi, Jung Sun Kim, Chang-Koo Shim, Suk-Jae Chung & Dae-Duk Kim
Pages: 243-251
Published online: 03 Dec 2010
AbstractforPharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol | Full Text | References | PDF (713.6 KB)
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Article
The multiple-dosing pharmacokinetics of artemether, artesunate, and their metabolite dihydroartemisinin in rats
J. Xing, K.H. Bai, T. Liu, R.L. Wang, L.F. Zhang & S.Q. Zhang
Pages: 252-258
Published online: 22 Dec 2010
AbstractforThe multiple-dosing pharmacokinetics of artemether, artesunate, and their metabolite dihydroartemisinin in rats | Full Text | References | PDF (686.8 KB)
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