Xenobiotica, Volume 43, Issue 3 (2013)

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Xenobiotica, Volume 43, Issue 3 (2013)

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General Xenobiochemistry

Article
Mycophenolic acid glucuronide is transported by multidrug resistance-associated protein 2 and this transport is not inhibited by cyclosporine, tacrolimus or sirolimus
Chirag G. Patel, Ken Ogasawara & Fatemeh Akhlaghi
Pages: 229-235
Published online: 30 Aug 2012
AbstractforMycophenolic acid glucuronide is transported by multidrug resistance-associated protein 2 and this transport is not inhibited by cyclosporine, tacrolimus or sirolimus | Full Text | References | PDF (698.3 KB)
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Article
Elucidation of the mechanism of ribose conjugation in a pyrazole-containing compound in rodent liver
Hoa Le, Kevin A. Ford, S. Cyrus Khojasteh & Peter W. Fan
Pages: 236-245
Published online: 30 Aug 2012
AbstractforElucidation of the mechanism of ribose conjugation in a pyrazole-containing compound in rodent liver | Full Text | References | PDF (1.9 MB)
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Article
Alteration in plasma protein binding properties of propranolol and flurbiprofen during development of adjuvant-induced arthritis in rats
Atsushi Kawase, Hiroyuki Ikuta, Satoshi Uno, Kana Yamamoto, Naomi Akitsu, Tomoaki Nagao & Masahiro Iwaki
Pages: 246-252
Published online: 07 Aug 2012
AbstractforAlteration in plasma protein binding properties of propranolol and flurbiprofen during development of adjuvant-induced arthritis in rats | Full Text | References | PDF (1.3 MB)
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Article
Evaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect
Ling Li, Amr Nouraldeen & Alan G. E. Wilson
Pages: 253-262
Published online: 28 Aug 2012
AbstractforEvaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect | Full Text | References | PDF (990.3 KB)
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Article
Evaluation of bioreductive activation of anticancer drugs idarubicin and mitomycin C by NADH-cytochrome b5 reductase and cytochrome P450 2B4
Haydar Çelik & Emel Arinç
Pages: 263-275
Published online: 28 Aug 2012
AbstractforEvaluation of bioreductive activation of anticancer drugs idarubicin and mitomycin C by NADH-cytochrome b5 reductase and cytochrome P450 2B4 | Full Text | References | PDF (769 KB) | Supplemental
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Clinical Pharmacokinetics and Metabolism

Article
Clinical pharmacology of etoposide in children undergoing autologous stem cell transplantation for various solid tumours
Gautam Baheti, Timothy R. McGuire, Jasmine P. Davda, Konstantine K. Manouilov, Donna Wall, Peter R. Gwilt & Bruce B. Gordon
Pages: 276-282
Published online: 29 Aug 2012
AbstractforClinical pharmacology of etoposide in children undergoing autologous stem cell transplantation for various solid tumours | Full Text | References | PDF (721.1 KB)
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Article
Disposition and metabolism of [14C]PTZ601 in healthy volunteers
J. Flarakos, L. S. L. Ting, Y. Du, D. S. Stein, C. V. Reynolds, M. Patel, S. Roy & J. B. Mangold
Pages: 283-292
Published online: 29 Aug 2012
AbstractforDisposition and metabolism of [14C]PTZ601 in healthy volunteers | Full Text | References | PDF (1.3 MB)
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Animal Pharmacokinetics and Metabolisms

Article
Toxicokinetics of methyleugenol in F344 rats and B6C3F1 mice
S. Peter Hong, Alfred F. Fuciarelli, Jerry D. Johnson, Steven W. Graves, Derrick J. Bates, Suramya Waidyanatha & Cynthia S. Smith
Pages: 293-302
Published online: 10 Aug 2012
AbstractforToxicokinetics of methyleugenol in F344 rats and B6C3F1 mice | Full Text | References | PDF (1.3 MB)
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Article
Effects of single or repeated silymarin administration on pharmacokinetics of risperidone and its major metabolite, 9-hydroxyrisperidone in rats
Kyoung Sin Lee, Song Wha Chae, Joon Hee Park, Jung Hyun Park, Jong Min Choi, Sandy (Jeong Yeon) Rhie & Hwa Jeong Lee
Pages: 303-310
Published online: 04 Dec 2012
AbstractforEffects of single or repeated silymarin administration on pharmacokinetics of risperidone and its major metabolite, 9-hydroxyrisperidone in rats | Full Text | References | PDF (710.9 KB)
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