Xenobiotica, Volume 43, Issue 5 (2013)

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Xenobiotica, Volume 43, Issue 5 (2013)

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General Xenobiochemistry

Article
Interspecies variation in the metabolism of zoniporide by aldehyde oxidase
Deepak Dalvie, Cathie Xiang, Ping Kang & Sue Zhou
Pages: 399-408
Published online: 10 Oct 2012
AbstractforInterspecies variation in the metabolism of zoniporide by aldehyde oxidase | Full Text | References | PDF (1.2 MB)
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Article
The fungus Cunninghamella elegans can produce human and equine metabolites of selective androgen receptor modulators (SARMs)
Axel Rydevik, Mario Thevis, Oliver Krug, Ulf Bondesson & Mikael Hedeland
Pages: 409-420
Published online: 15 Nov 2012
AbstractforThe fungus Cunninghamella elegans can produce human and equine metabolites of selective androgen receptor modulators (SARMs) | Full Text | References | PDF (902.2 KB)
  • 207 Views
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Article
In vitro models of xenobiotic metabolism in trout for use in environmental bioaccumulation studies
Chibuzor Uchea, Sunil Sarda, Timothy Schulz-Utermoehl, Stewart Owen & Kevin J. Chipman
Pages: 421-431
Published online: 15 Nov 2012
AbstractforIn vitro models of xenobiotic metabolism in trout for use in environmental bioaccumulation studies | Full Text | References | PDF (727.3 KB)
  • 348 Views
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Clinical Pharmacokinetics and Metabolism

Article
Pharmacokinetics and metabolism of [14C]anagliptin, a novel dipeptidyl peptidase-4 inhibitor, in humans
Shinji Furuta, Clair Smart, Andrew Hackett, Rajdeep Benning & Steve Warrington
Pages: 432-442
Published online: 18 Oct 2012
AbstractforPharmacokinetics and metabolism of [14C]anagliptin, a novel dipeptidyl peptidase-4 inhibitor, in humans | Full Text | References | PDF (884.7 KB)
  • 573 Views
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Article
Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer
Yanli Deng, Caroline Sychterz, A. Benjamin Suttle, Mohammed M. Dar, David Bershas, Kitaw Negash, Yanwen Qian, Emile P. Chen, Peter D. Gorycki & May Y. K. Ho
Pages: 443-453
Published online: 16 Nov 2012
AbstractforBioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer | Full Text | References | PDF (899.6 KB)
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Animal Pharmacokinetics and Metabolism

Article
Identification of ginkgolic acid (15:1) metabolites in rats following oral administration by high-performance liquid chromatography coupled to tandem mass spectrometry
Hongjun Xia, Zhenhua Liu, Haihong Hu, Hui Zhou & Su Zeng
Pages: 454-460
Published online: 04 Dec 2012
AbstractforIdentification of ginkgolic acid (15:1) metabolites in rats following oral administration by high-performance liquid chromatography coupled to tandem mass spectrometry | Full Text | References | PDF (1 MB)
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Article
Identification of the metabolites of lesogaberan using linear trap quadrupole orbitrap mass spectrometry and hydrophilic interaction liquid chromatography
Anja Ekdahl, Ann Aurell-Holmberg & Neal Castagnoli Jr
Pages: 461-467
Published online: 03 Oct 2012
AbstractforIdentification of the metabolites of lesogaberan using linear trap quadrupole orbitrap mass spectrometry and hydrophilic interaction liquid chromatography | Full Text | References | PDF (935.5 KB) | Supplemental
  • 210 Views
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Article
A new approach to predicting human hepatic clearance of CYP3A4 substrates using monkey pharmacokinetic data
Kotaro Ogawa, Motohiro Kato, Takao Houjo & Masaki Ishigai
Pages: 468-478
Published online: 15 Nov 2012
AbstractforA new approach to predicting human hepatic clearance of CYP3A4 substrates using monkey pharmacokinetic data | Full Text | References | PDF (923.8 KB)
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Article
Isolation and identification of phase I metabolites of resibufogenin in rats
Z.-T. Zhu, S. Deng, D. Liu, B.-J. Zhang, H.-Z. Sun, Y. Tian, C.-Y. Wang, Li Wang & X.-C. Ma
Pages: 479-485
Published online: 15 Nov 2012
AbstractforIsolation and identification of phase I metabolites of resibufogenin in rats | Full Text | References | PDF (863.5 KB)
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