Xenobiotica, Volume 44, Issue 12 (2014)

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Xenobiotica, Volume 44, Issue 12 (2014)

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Topics in Xenobiochemistry

Review Article
Xenobiotic–urea conjugates; chemical or biological?
Stephen C. Mitchell
Pages: 1055-1066
Published online: 21 Aug 2014
AbstractforXenobiotic–urea conjugates; chemical or biological? | Full Text | References | PDF (307.1 KB)
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General Xenobiochemistry

Article
Comparative analysis of glucuronidation of ethanol in treeshrews, rats and humans
Jiangnan Fu, Hongming Liu, Huijie Xing, Hua Sun, Zhiguo Ma & Baojian Wu
Pages: 1067-1073
Published online: 06 Jun 2014
AbstractforComparative analysis of glucuronidation of ethanol in treeshrews, rats and humans | Full Text | References | PDF (331.5 KB)
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Research Article

Article
The complex degradation and metabolism of quercetin in rat hepatocyte incubations
Khaled Omar, M. Helen Grant, Catherine Henderson & David George Watson
Pages: 1074-1082
Published online: 24 Jun 2014
AbstractforThe complex degradation and metabolism of quercetin in rat hepatocyte incubations | Full Text | References | PDF (654.7 KB)
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Clinical Pharmacokinetics and Metabolism

Article
Metabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man
Peter Ballard, Helen C. Swaisland, Michael D. Malone, Sunil Sarda, Serban Ghiorghiu & Darren Wilbraham
Pages: 1083-1098
Published online: 09 Jul 2014
AbstractforMetabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man | Full Text | References | PDF (843.9 KB) | Supplemental
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Animal Pharmacokinetics and Metabolism

Article
Pharmacokinetics and tissue distribution of ginsenoside Rh2 and Rg3 epimers after oral administration of BST204, a purified ginseng dry extract, in rats
Soo Hyeon Bae, Jung Bae Park, Yu Fen Zheng, Min Jung Jang, Sun Ok Kim, Jeom Yong Kim, Young Hyo Yoo, Kee Dong Yoon, Euichaul Oh & Soo Kyung Bae
Pages: 1099-1107
Published online: 16 Jun 2014
AbstractforPharmacokinetics and tissue distribution of ginsenoside Rh2 and Rg3 epimers after oral administration of BST204, a purified ginseng dry extract, in rats | Full Text | References | PDF (645.6 KB)
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Research Article

Article
Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats
Murali Subramanian, Vishwanath Kurawattimath, Krishna Pocha, Chris Freeden, Indranil Rao, T. Thanga Mariappan, Punit H. Marathe, Reeba K. Vikramadithyan, Pamela Abraham, Chetan P. Kulkarni, Prasanna Katnapally, Ravikumar Nutakki, Sundeep Paruchury, Priyadeep Bhutani & Sandhya Mandlekar
Pages: 1108-1116
Published online: 20 Jun 2014
AbstractforRole of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats | Full Text | References | PDF (361.1 KB) | Supplemental
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Article
Pharmacokinetics and disposition of dalcetrapib in rats and monkeys
Hiroaki Takubo, Tomohiro Ishikawa, Olaf Kuhlmann, Hiroyuki Nemoto, Tomoyuki Noguchi, Toyomichi Nanayama, Hiroshi Komura & Motohiro Kogayu
Pages: 1117-1126
Published online: 23 Jun 2014
AbstractforPharmacokinetics and disposition of dalcetrapib in rats and monkeys | Full Text | References | PDF (432.2 KB)
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Article
Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody
Kenta Haraya, Tatsuhiko Tachibana, Masahiko Nanami & Masaki Ishigai
Pages: 1127-1134
Published online: 17 Jul 2014
AbstractforApplication of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody | Full Text | References | PDF (437.3 KB)
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Xenobiotic Transporters

Article
Clarification of P-glycoprotein inhibition-related drug–drug interaction risks based on a literature search of the clinical information
Yukari Umeyama, Yasushi Fujioka & Teruaki Okuda
Pages: 1135-1144
Published online: 17 Jun 2014
AbstractforClarification of P-glycoprotein inhibition-related drug–drug interaction risks based on a literature search of the clinical information | Full Text | References | PDF (174.2 KB)
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Acknowledgements

Acknowledgements
Pages: 1145-1147
Published online: 07 Nov 2014
First Page PreviewforAcknowledgements | Full Text | PDF (57.8 KB)
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