Xenobiotica, Volume 45, Issue 10 (2015)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Xenobiotica, Volume 45, Issue 10 (2015)

See all volumes and issues
Vol 54, 2024 Vol 53, 2023 Vol 52, 2022 Vol 51, 2021 Vol 50, 2020 Vol 49, 2019 Vol 48, 2018 Vol 47, 2017 Vol 46, 2016 Volume 45, 2015 Vol 44, 2014 Vol 43, 2013 Vol 42, 2012 Vol 41, 2011 Vol 40, 2010 Vol 39, 2009 Vol 38, 2008 Vol 37, 2007 Vol 36, 2006 Vol 35, 2005 Vol 34, 2004 Vol 33, 2003 Vol 32, 2002 Vol 31, 2001 Vol 30, 2000 Vol 29, 1999 Vol 28, 1998 Vol 27, 1997 Vol 26, 1996 Vol 25, 1995 Vol 24, 1994 Vol 23, 1993 Vol 22, 1992 Vol 21, 1991 Vol 20, 1990 Vol 19, 1989 Vol 18, 1988 Vol 17, 1987 Vol 16, 1986 Vol 15, 1985 Vol 14, 1984 Vol 13, 1983 Vol 12, 1982 Vol 11, 1981 Vol 10, 1980 Vol 9, 1979 Vol 8, 1978 Vol 7, 1977 Vol 6, 1976 Vol 5, 1975 Vol 4, 1974 Vol 3, 1973 Vol 2, 1972 Vol 1, 1971
Download citations Download PDFs Download issue

General Xenobiochemistry

Article
Characterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins
Andrew Rowland, David Hallifax, Matthew R. Nussio, Joseph G. Shapter, Peter I. Mackenzie, J. Brian Houston, Kathleen M. Knights & John O. Miners
Pages: 847-857
Published online: 24 Mar 2015
AbstractforCharacterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins | Full Text | References | PDF (648.7 KB)
  • 434 Views
  • 5 CrossRef citations
  • 0Altmetric
Article
Irreversible binding of an anticancer compound (BI-94) to plasma proteins
Nagsen Gautam, Rhishikesh Thakare, Sandeep Rana, Amarnath Natarajan & Yazen Alnouti
Pages: 858-873
Published online: 14 Apr 2015
AbstractforIrreversible binding of an anticancer compound (BI-94) to plasma proteins | Full Text | References | PDF (3.3 MB)
  • 238 Views
  • 6 CrossRef citations
  • 0Altmetric
Article
Decreased elimination clearance of midazolam by doxorubicin through reductions in the metabolic activity of hepatic CYP3A in rats
Katsuhito Nagai, Natsumi Yoshida, Maho Kiyama, Keita Kasahara, Ayumi Yamamura & Hiroki Konishi
Pages: 874-880
Published online: 08 Jun 2015
AbstractforDecreased elimination clearance of midazolam by doxorubicin through reductions in the metabolic activity of hepatic CYP3A in rats | Full Text | References | PDF (614.9 KB)
  • 188 Views
  • 5 CrossRef citations
  • 0Altmetric
Article
Human plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling
Satomi Shida, Masahiro Utoh, Norie Murayama, Makiko Shimizu, Yasuhiro Uno & Hiroshi Yamazaki
Pages: 881-886
Published online: 15 Jun 2015
AbstractforHuman plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling | Full Text | References | PDF (1.3 MB)
  • 511 Views
  • 17 CrossRef citations
  • 0Altmetric

Clinical Pharmacokinetics and Metabolism

Article
Human mass balance, metabolite profile and identification of metabolic enzymes of [14C]ASP015K, a novel oral janus kinase inhibitor
Kazuo Oda, Ying J. Cao, Taiji Sawamoto, Naoyuki Nakada, Ogert Fisniku, Yasuhisa Nagasaka & Kin-ya Sohda
Pages: 887-902
Published online: 19 May 2015
AbstractforHuman mass balance, metabolite profile and identification of metabolic enzymes of [14C]ASP015K, a novel oral janus kinase inhibitor | Full Text | References | PDF (2 MB)
  • 771 Views
  • 19 CrossRef citations
  • 0Altmetric

Animal Pharmacokinetics and Metabolism

Article
Distribution and pharmacokinetics of etamicastat and its N-acetylated metabolite (BIA 5-961) in dog and monkey
A. I. Loureiro & P. Soares-da-Silva
Pages: 903-911
Published online: 14 Apr 2015
AbstractforDistribution and pharmacokinetics of etamicastat and its N-acetylated metabolite (BIA 5-961) in dog and monkey | Full Text | References | PDF (600.8 KB)
  • 148 Views
  • 1 CrossRef citations
  • 0Altmetric
Article
Pharmacokinetics and tissue distribution of the new non-imidazole histamine H3 receptor antagonist 1-[3-(4-tert-butylphenoxy) propyl]piperidine in rats
Malgorzata Szafarz, Agata Kryczyk, Dorota Lazewska, Katarzyna Kiec-Kononowicz & Elzbieta Wyska
Pages: 912-920
Published online: 14 Apr 2015
AbstractforPharmacokinetics and tissue distribution of the new non-imidazole histamine H3 receptor antagonist 1-[3-(4-tert-butylphenoxy) propyl]piperidine in rats | Full Text | References | PDF (386.8 KB)
  • 158 Views
  • 3 CrossRef citations
  • 0Altmetric

Molecular Toxicology

Article
Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells
Yuchao Xie, Mitchell R. McGill, Sarah F. Cook, Matthew R. Sharpe, Robert D. Winefield, Diana G. Wilkins, Douglas E. Rollins & Hartmut Jaeschke
Pages: 921-929
Published online: 14 Apr 2015
AbstractforTime course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells | Full Text | References | PDF (360.9 KB)
  • 494 Views
  • 49 CrossRef citations
  • 0Altmetric
Article
Modulation of aryl hydrocarbon receptor regulated genes by acute administration of trimethylarsine oxide in the lung, kidney and heart of C57BL/6 mice
Osama H. Elshenawy & Ayman O. S. El-Kadi
Pages: 930-943
Published online: 04 Jun 2015
AbstractforModulation of aryl hydrocarbon receptor regulated genes by acute administration of trimethylarsine oxide in the lung, kidney and heart of C57BL/6 mice | Full Text | References | PDF (945.2 KB)
  • 303 Views
  • 8 CrossRef citations
  • 0Altmetric

Explore articles

Explore the most recently published articles

Developmental stage and infection status may affect drug distribution in the prostate of rats
Ziyang Xu et al.
Article | Published online: 25 Apr 2024
Exploring precision-cut liver slices for comparative xenobiotic metabolism profiling in swine and cattle
Paula Ichinose et al.
Article | Published online: 25 Apr 2024
Academic foreign compound metabolism – ‘quo vadis’?
S. C. Mitchell et al.
Rapid Communication | Published online: 24 Apr 2024
Open Access
mRNA expression levels of cytochrome P450 CYP1A2, CYP3A4, and CYP3A5 in the epidermis: a focus on individual differences among Japanese individuals
Hiroko Makihara et al.
Article | Published online: 24 Apr 2024
View all latest articles