Xenobiotica, Volume 46, Issue 7 (2016)

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Xenobiotica, Volume 46, Issue 7 (2016)

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Obituary

Obituary
Professor John William Gorrod PhD, DSc, MPS(hon), FKC, FSP, FRCPath, 1931–2015
Maurice Smith & Laurence Patterson
Pages: 571-572
Published online: 11 Apr 2016
CitationforProfessor John William Gorrod PhD, DSc, MPS(hon), FKC, FSP, FRCPath, 1931–2015 | Full Text | PDF (446.7 KB)
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General Xenobiochemistry

Article
Caffeine 7-N-demethylation and C-8-oxidation mediated by liver microsomal cytochrome P450 enzymes in common marmosets
Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Takako Suzuki, Masahiro Utoh, Erika Sasaki & Hiroshi Yamazaki
Pages: 573-578
Published online: 27 Oct 2015
AbstractforCaffeine 7-N-demethylation and C-8-oxidation mediated by liver microsomal cytochrome P450 enzymes in common marmosets | Full Text | References | PDF (330 KB)
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Article
Species differences in metabolism of ripasudil (K-115) are attributed to aldehyde oxidase
Tomoyuki Isobe, Masayuki Ohta, Yoshio Kaneko & Hiroyuki Kawai
Pages: 579-590
Published online: 18 Dec 2015
AbstractforSpecies differences in metabolism of ripasudil (K-115) are attributed to aldehyde oxidase | Full Text | References | PDF (590.8 KB) | Supplemental
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Article
Tissue-specific regulation of CYP3A by hydrolysable tannins in male pigs
Galia Zamaratskaia, Martin Krøyer Rasmussen, Martin Škrlep, Nina Batorek Lukač, Dejan Škorjanc & Marjeta Čandek-Potokar
Pages: 591-596
Published online: 02 Nov 2015
AbstractforTissue-specific regulation of CYP3A by hydrolysable tannins in male pigs | Full Text | References | PDF (272.9 KB) | Supplemental
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Article
Population pharmacokinetic modelling and simulation of 5-fluorouracil incorporating a circadian rhythm in rats
Shinji Kobuchi, Yukako Ito, Yuya Nakano & Toshiyuki Sakaeda
Pages: 597-604
Published online: 27 Oct 2015
AbstractforPopulation pharmacokinetic modelling and simulation of 5-fluorouracil incorporating a circadian rhythm in rats | Full Text | References | PDF (669.8 KB)
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Article
Species and tissue differences in serotonin glucuronidation
Yukiko Sakakibara, Miki Katoh, Taisho Kawayanagi & Masayuki Nadai
Pages: 605-611
Published online: 02 Nov 2015
AbstractforSpecies and tissue differences in serotonin glucuronidation | Full Text | References | PDF (563.3 KB)
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Article
Sulfation of 6-hydroxymelatonin, N-acetylserotonin and 4-hydroxyramelteon by the human cytosolic sulfotransferases (SULTs)
Lijun Luo, Chunyang Zhou, Katsuhisa Kurogi, Yoichi Sakakibara, Masahito Suiko & Ming-Cheh Liu
Pages: 612-619
Published online: 17 Nov 2015
AbstractforSulfation of 6-hydroxymelatonin, N-acetylserotonin and 4-hydroxyramelteon by the human cytosolic sulfotransferases (SULTs) | Full Text | References | PDF (549.3 KB)
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Animal Pharmacokinetics and Metabolism

Article
Pharmacokinetics of isoforskolin after administration via different routes in guinea pigs
Tingting Feng, Yong Li, Jun Chen, Yong Chen, Jianming Huang & Weiyu Weng
Pages: 620-626
Published online: 02 Nov 2015
AbstractforPharmacokinetics of isoforskolin after administration via different routes in guinea pigs | Full Text | References | PDF (576.9 KB) | Supplemental
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Article
Effect of long-term coadministration of compound glycyrrhizin tablets on the pharmacokinetics of mycophenolic acid in rats
Qingfeng Liu, Zheng Jiao, Mingkang Zhong, Ming Zhang, Fang Geng & Hui Zhao
Pages: 627-633
Published online: 02 Nov 2015
AbstractforEffect of long-term coadministration of compound glycyrrhizin tablets on the pharmacokinetics of mycophenolic acid in rats | Full Text | References | PDF (276 KB)
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Pharmacogenetics

Article
Genetic polymorphisms of the drug-metabolizing enzyme CYP2C19 in the Uyghur population in northwest China
Tianbo Jin, Mingxia Zhang, Hua Yang, Tingting Geng, Ning Zhang, Tian Feng, Yajuan Ma, Dongya Yuan & Longli Kang
Pages: 634-640
Published online: 02 Nov 2015
AbstractforGenetic polymorphisms of the drug-metabolizing enzyme CYP2C19 in the Uyghur population in northwest China | Full Text | References | PDF (519.1 KB)
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Xenobiotic Transporters

Article
Interaction of green tea catechins with renal organic cation transporter 2
Chaliya Jaiyen, Promsuk Jutabha, Naohiko Anzai, Anusorn Lungkaphin, Sunhapas Soodvilai & Chutima Srimaroeng
Pages: 641-650
Published online: 17 Nov 2015
AbstractforInteraction of green tea catechins with renal organic cation transporter 2 | Full Text | References | PDF (653.5 KB)
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Article
The drug–drug interaction of sorafenib mediated by P-glycoprotein and CYP3A4
Xianming Wang, Xiang Zhang, Xinhui Huang, Yuntong Li, Mengchao Wu & Jingfeng Liu
Pages: 651-658
Published online: 18 Nov 2015
AbstractforThe drug–drug interaction of sorafenib mediated by P-glycoprotein and CYP3A4 | Full Text | References | PDF (667.4 KB)
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Topics in Xenobiochemistry

The usefulness of Øie–Tozer’s model in deriving pharmacokinetic changes in response to changes in the concentration of drug-binding plasma protein
Andreas Svennebring
Pages: 659-663
Published online: 02 Nov 2015
AbstractforThe usefulness of Øie–Tozer’s model in deriving pharmacokinetic changes in response to changes in the concentration of drug-binding plasma protein | Full Text | References | PDF (206 KB)
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The 44th annual open meeting of the Drug Metabolism Discussion Group (DMDG) at Robinson College, Cambridge, UK, September 16th–18th, 2015
Ian D. Wilson
Pages: 664-666
Published online: 11 Apr 2016
First Page PreviewforThe 44th annual open meeting of the Drug Metabolism Discussion Group (DMDG) at Robinson College, Cambridge, UK, September 16th–18th, 2015 | Full Text | PDF (114.2 KB)
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