Xenobiotica, Volume 47, Issue 11 (2017)

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Xenobiotica, Volume 47, Issue 11 (2017)

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General Xenobiochemistry

Article
Assessment of liver slices for research on metabolic drug–drug interactions in cattle
Paula Viviani, Adrián L. Lifschitz, Jorge P. García, María Laura Maté, Miguel A. Quiroga, Carlos E. Lanusse & Guillermo L. Virkel
Pages: 933-942
Published online: 12 Jan 2017
AbstractforAssessment of liver slices for research on metabolic drug–drug interactions in cattle | Full Text | References | PDF (1.2 MB)
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Article
Stereoselective hepatic disposition of ibuprofen in the perfused liver of rat with adjuvant-induced arthritis
Misato Uraki, Atsushi Kawase & Masahiro Iwaki
Pages: 943-950
Published online: 10 Nov 2016
AbstractforStereoselective hepatic disposition of ibuprofen in the perfused liver of rat with adjuvant-induced arthritis | Full Text | References | PDF (449.7 KB)
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Article
Functional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates
Gaku Okamatsu, Kei Kawakami, Tetsuya Komatsu, Takio Kitazawa, Yasuhiro Uno & Hiroki Teraoka
Pages: 951-961
Published online: 30 Nov 2016
AbstractforFunctional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates | Full Text | References | PDF (302.4 KB)
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Animal Pharmacokinetics and Metabolism

Article
Evaluation of the metabolism, bioactivation and pharmacokinetics of triaminopyrimidine analogs toward selection of a potential candidate for antimalarial therapy
Abhishek Srivastava, Vijender Panduga, Ramanatha Saralaya, Prabhakar K. R.Shahul Hameed, Suresh Solapure & Vinayak P. Hosagrahara
Pages: 962-972
Published online: 14 Nov 2016
AbstractforEvaluation of the metabolism, bioactivation and pharmacokinetics of triaminopyrimidine analogs toward selection of a potential candidate for antimalarial therapy | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Effect of ferulic acid on the brain pharmacokinetics of tetramethylpyrazine in conscious rats
Yinai Wu, Fengyun Liao, Weiguo Liao, Jianye Yu, Xingyun Deng, Huazhu Zheng, YingJiao Meng & Lisheng Wang
Pages: 973-979
Published online: 25 Jul 2017
AbstractforEffect of ferulic acid on the brain pharmacokinetics of tetramethylpyrazine in conscious rats | Full Text | References | PDF (818.6 KB)
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Article
Excretion and toxicity evaluation of 131I-Sennoside A as a necrosis-avid agent
Zhiqi Yin, Lidan Sun, Qiaomei Jin, Shaoli Song, Yuanbo Feng, Hong Liao, Yicheng Ni, Jian Zhang & Wei Liu
Pages: 980-988
Published online: 13 Mar 2017
AbstractforExcretion and toxicity evaluation of 131I-Sennoside A as a necrosis-avid agent | Full Text | References | PDF (1.2 MB)
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Xenobiotic Transporters

Article
Differential regulation of intestinal efflux transporters by pregnancy in mice
Jamie E. Moscovitz, Gabriel Yarmush, Guadalupe Herrera-Garcia, Grace L. Guo & Lauren M. Aleksunes
Pages: 989-997
Published online: 03 Jan 2017
AbstractforDifferential regulation of intestinal efflux transporters by pregnancy in mice | Full Text | References | PDF (737.6 KB) | Supplemental
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Article
Multidrug and toxin extrusion protein 1-mediated interaction of metformin and Scutellariae radix in rats
Sreymom Yim, Byoung Hoon You, Hee-Sung Chae, Young-Won Chin, Hojun Kim, Han Seok Choi & Young Hee Choi
Pages: 998-1007
Published online: 28 Nov 2016
AbstractforMultidrug and toxin extrusion protein 1-mediated interaction of metformin and Scutellariae radix in rats | Full Text | References | PDF (432.1 KB) | Supplemental
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Article
ABCC2 (1249G > A) polymorphism implicates altered transport activity for sorafenib
Danyun Wei, Hong Zhang, Rui Peng, Cuiyuan Huang & Ruidan Bai
Pages: 1008-1014
Published online: 07 Dec 2016
AbstractforABCC2 (1249G > A) polymorphism implicates altered transport activity for sorafenib | Full Text | References | PDF (549.1 KB)
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Topics in Xenobiochemistry

Review
Comparative pharmacokinetics of three SGLT-2 inhibitors sergliflozin, remogliflozin and ertugliflozin: an overview
Ranjeet Prasad Dash, R. Jayachandra Babu & Nuggehally R. Srinivas
Pages: 1015-1026
Published online: 28 Oct 2016
AbstractforComparative pharmacokinetics of three SGLT-2 inhibitors sergliflozin, remogliflozin and ertugliflozin: an overview | Full Text | References | PDF (249.3 KB)
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