Xenobiotica, Volume 49, Issue 3 (2019)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Xenobiotica, Volume 49, Issue 3 (2019)

See all volumes and issues
Vol 54, 2024 Vol 53, 2023 Vol 52, 2022 Vol 51, 2021 Vol 50, 2020 Volume 49, 2019 Vol 48, 2018 Vol 47, 2017 Vol 46, 2016 Vol 45, 2015 Vol 44, 2014 Vol 43, 2013 Vol 42, 2012 Vol 41, 2011 Vol 40, 2010 Vol 39, 2009 Vol 38, 2008 Vol 37, 2007 Vol 36, 2006 Vol 35, 2005 Vol 34, 2004 Vol 33, 2003 Vol 32, 2002 Vol 31, 2001 Vol 30, 2000 Vol 29, 1999 Vol 28, 1998 Vol 27, 1997 Vol 26, 1996 Vol 25, 1995 Vol 24, 1994 Vol 23, 1993 Vol 22, 1992 Vol 21, 1991 Vol 20, 1990 Vol 19, 1989 Vol 18, 1988 Vol 17, 1987 Vol 16, 1986 Vol 15, 1985 Vol 14, 1984 Vol 13, 1983 Vol 12, 1982 Vol 11, 1981 Vol 10, 1980 Vol 9, 1979 Vol 8, 1978 Vol 7, 1977 Vol 6, 1976 Vol 5, 1975 Vol 4, 1974 Vol 3, 1973 Vol 2, 1972 Vol 1, 1971
Download citations Download PDFs Download issue

General Xenobiochemistry

Article
Porcine interleukin-6 enhances the expression of CYP2C33 through a constitutive androstane receptor/retinoid X receptor-mediated pathway
Lixia Xie, Yucheng He, Xiaoqiao Zhou, Xiaowen Li, Xiue Jin, Xiliang Wang & Deshi Shi
Pages: 257-264
Published online: 27 Feb 2018
AbstractforPorcine interleukin-6 enhances the expression of CYP2C33 through a constitutive androstane receptor/retinoid X receptor-mediated pathway | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 119 Views
  • 3 CrossRef citations
  • 0Altmetric
Article
Marmoset cytochrome P450 2B6, a propofol hydroxylase expressed in liver
Toru Oshio, Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki
Pages: 265-269
Published online: 21 Feb 2018
AbstractforMarmoset cytochrome P450 2B6, a propofol hydroxylase expressed in liver | Full Text | References | PDF (652.5 KB) | EPUB
  • 117 Views
  • 5 CrossRef citations
  • 0Altmetric
Article
Expression and activities of sulfotransferase in rat brain
Yuki Asai, Yukiko Sakakibara, Miyabi Kondo, Masayuki Nadai & Miki Katoh
Pages: 270-275
Published online: 26 Feb 2018
AbstractforExpression and activities of sulfotransferase in rat brain | Full Text | References | PDF (746.1 KB) | EPUB
  • 152 Views
  • 1 CrossRef citations
  • 0Altmetric
Article
Identification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin
Chunli Qi, Jiangnan Fu, Huinan Zhao, Huijie Xing, Dong Dong & Baojian Wu
Pages: 276-283
Published online: 27 Feb 2018
AbstractforIdentification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin | Full Text | References | PDF (892.7 KB) | EPUB
  • 221 Views
  • 16 CrossRef citations
  • 0Altmetric
Article
Cross-species comparison of the metabolism and excretion of selexipag
Tomohiko Ichikawa, Tetsuhiro Yamada, Alexander Treiber, Carmela Gnerre, Jérôme Segrestaa, Swen Seeland & Kiyoko Nonaka
Pages: 284-301
Published online: 21 Mar 2018
AbstractforCross-species comparison of the metabolism and excretion of selexipag | Full Text | References | PDF (2.4 MB) | EPUB
  • 357 Views
  • 3 CrossRef citations
  • 0Altmetric
Article
Identification and human exposure prediction of two aldehyde oxidase-mediated metabolites of a methylquinoline-containing drug candidate
Austin C. Li, Donghui Cui, Erya Yu, Kyle Dobson, Edward T. Hellriegel & Philmore Robertson Jr
Pages: 302-312
Published online: 14 Mar 2018
AbstractforIdentification and human exposure prediction of two aldehyde oxidase-mediated metabolites of a methylquinoline-containing drug candidate | Full Text | References | PDF (1.4 MB) | EPUB
  • 351 Views
  • 7 CrossRef citations
  • 0Altmetric

Clinical Pharmacokinetis and Metabolism

Article
Pharmacokinetics and tolerability of cinitapride in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study
Xiong Zhang, Ying Wang, Junlin Cheng, Yunfang Hu, Jianghui Liu, Jing Chen, Xingye Yang & Hongwei Fan
Pages: 313-321
Published online: 28 Mar 2018
AbstractforPharmacokinetics and tolerability of cinitapride in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study | Full Text | References | PDF (1.7 MB) | EPUB
  • 142 Views
  • 1 CrossRef citations
  • 0Altmetric

Animal Pharmacokinetics and Metabolism

Article
Pharmacokinetics and distribution of schisandrol A and its major metabolites in rats
Xu Liu, Lixin Cong, Chunmei Wang, He Li, Chengyi Zhang, Xingang Guan, Peng Liu, Yu Xie, Jianguang Chen & Jinghui Sun
Pages: 322-331
Published online: 16 Jan 2019
AbstractforPharmacokinetics and distribution of schisandrol A and its major metabolites in rats | Full Text | References | PDF (746.3 KB) | EPUB
  • 171 Views
  • 15 CrossRef citations
  • 0Altmetric
Article
Metabolic disposition of WTX101 (bis-choline tetrathiomolybdate) in a rat model of Wilson disease
Thomas Plitz & Lee Boyling
Pages: 332-338
Published online: 27 Feb 2018
AbstractforMetabolic disposition of WTX101 (bis-choline tetrathiomolybdate) in a rat model of Wilson disease | Full Text | References | PDF (1.3 MB) | EPUB
  • 311 Views
  • 7 CrossRef citations
  • 0Altmetric
Article
Pharmacokinetics and brain penetration study of chlorogenic acid in rats
Gaurav Kumar, Pankaj Paliwal, Sumedha Mukherjee, Nishant Patnaik, Sairam Krishnamurthy & Ranjana Patnaik
Pages: 339-345
Published online: 21 Mar 2018
AbstractforPharmacokinetics and brain penetration study of chlorogenic acid in rats | Full Text | References | PDF (1.5 MB) | EPUB
  • 250 Views
  • 28 CrossRef citations
  • 0Altmetric
Article
Distribution and metabolism of 14C-sulfoquinovosylacylpropanediol (14C-SQAP) after a single intravenous administration in tumor-bearing mice
Tatsushi Ruike, Yoshihiro Kanai, Kazuki Iwabata, Yuki Matsumoto, Hiroshi Murata, Masahiro Ishima, Keisuke Ohta, Masahiko Oshige, Shinji Katsura, Koji Kuramochi, Shinji Kamisuki, Hiroeki Sahara, Masahiko Miura, Fumio Sugawara & Kengo Sakaguchi
Pages: 346-362
Published online: 24 Apr 2018
AbstractforDistribution and metabolism of 14C-sulfoquinovosylacylpropanediol (14C-SQAP) after a single intravenous administration in tumor-bearing mice | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 153 Views
  • 5 CrossRef citations
  • 0Altmetric

Xenobiotic Transporters

Article
Interactions of organophosphorus pesticides with solute carrier (SLC) drug transporters
Lisa Chedik, Arnaud Bruyere & Olivier Fardel
Pages: 363-374
Published online: 06 Mar 2018
AbstractforInteractions of organophosphorus pesticides with solute carrier (SLC) drug transporters | Full Text | References | PDF (1.8 MB) | EPUB
  • 491 Views
  • 24 CrossRef citations
  • 0Altmetric

Pharmacogenetics

Article
Effects of CYP3A4*1G and CYP3A5*3 polymorphisms on pharmacokinetics of tylerdipine hydrochloride in healthy Chinese subjects
Sufeng Zhou, Mingxue Tao, Yuanyuan Wang, Lu Wang, Lijun Xie, Juan Chen, Yuqing Zhao, Yun Liu, Hongwen Zhang, Ning Ou, Guangji Wang, Feng Shao & Jiye Aa
Pages: 375-380
Published online: 28 Mar 2018
AbstractforEffects of CYP3A4*1G and CYP3A5*3 polymorphisms on pharmacokinetics of tylerdipine hydrochloride in healthy Chinese subjects | Full Text | References | PDF (737.4 KB) | EPUB | Supplemental
  • 160 Views
  • 2 CrossRef citations
  • 0Altmetric

Explore articles

Explore the most recently published articles

Translational PK/PD framework for antibody-drug conjugates to inform drug discovery and development
Michael Z. Liao et al.
Review Article | Published online: 13 May 2024
A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin cleavable ADC linkers
Meghan E. Gray et al.
Article | Published online: 13 May 2024
Approaches to Improve the Translation of Safety, Pharmacokinetics and Therapeutic Index of ADCs
Qihong Huang et al.
Review Article | Published online: 11 May 2024
Pharmacokinetics of Intranasal Drugs, Still a Missed Opportunity?
Maria Luisa Sardu et al.
Review Article | Published online: 30 Apr 2024
View all latest articles