Xenobiotica, Volume 50, Issue 10 (2020)

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Xenobiotica, Volume 50, Issue 10 (2020)

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General Xenobiochemistry

Article
Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver
Mengjing Zhao, Huan Zhao, Luomin Lin, Yi Wang, Menglin Chen & Baojian Wu
Pages: 1139-1148
Published online: 16 Apr 2020
AbstractforNuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver | Full Text | References | PDF (1.8 MB) | EPUB
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Article
Assessment of in vitro inhibitory effects of novel anti MRSA benzoquinolizine fluoroquinolone WCK 771 (levonadifloxacin) and its metabolite on human liver cytochrome P450 enzymes
Rajesh Chavan, Vineet Zope, Nilesh Chavan, Javeed Shaikh, Kiran Patil, Ravindra Yeole, Sachin Bhagwat & Mahesh Patel
Pages: 1149-1157
Published online: 22 Apr 2020
AbstractforAssessment of in vitro inhibitory effects of novel anti MRSA benzoquinolizine fluoroquinolone WCK 771 (levonadifloxacin) and its metabolite on human liver cytochrome P450 enzymes | Full Text | References | PDF (2 MB) | EPUB
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Article
Preference for O-demethylation reactions in the oxidation of 2′-, 3′-, and 4′-methoxyflavones by human cytochrome P450 enzymes
Haruna Nagayoshi, Norie Murayama, Masaki Tsujino, Shigeo Takenaka, Jun Katahira, Vitchan Kim, Donghak Kim, Masayuki Komori, Hiroshi Yamazaki, F. Peter Guengerich & Tsutomu Shimada
Pages: 1158-1169
Published online: 30 Apr 2020
AbstractforPreference for O-demethylation reactions in the oxidation of 2′-, 3′-, and 4′-methoxyflavones by human cytochrome P450 enzymes | Full Text | References | PDF (3.7 MB) | EPUB
  • 164 Views
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Article
Inhibition of UDP-glucuronosyltransferases by different furoquinoline alkaloids
Yixuan Li, Weihua Zhang, Tingting Yin, Ce Wang, Feige Wang, Jing Sun, Lina Liu, Qinghuai Zhang & Chunze Zhang
Pages: 1170-1179
Published online: 05 May 2020
AbstractforInhibition of UDP-glucuronosyltransferases by different furoquinoline alkaloids | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Review
Molecular mechanisms of ethanol biotransformation: enzymes of oxidative and nonoxidative metabolic pathways in human
Grażyna Kubiak-Tomaszewska, Piotr Tomaszewski, Jan Pachecka, Marta Struga, Wioletta Olejarz, Magdalena Mielczarek-Puta & Grażyna Nowicka
Pages: 1180-1201
Published online: 13 May 2020
AbstractforMolecular mechanisms of ethanol biotransformation: enzymes of oxidative and nonoxidative metabolic pathways in human | Full Text | References | PDF (1.9 MB) | EPUB
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Article
In vitro effects of peimine on the activity of cytochrome P450 enzymes
Meng Li, Xiaoyan Liu, Yuzhen Wang & Xiuli Ju
Pages: 1202-1207
Published online: 05 May 2020
AbstractforIn vitro effects of peimine on the activity of cytochrome P450 enzymes | Full Text | References | PDF (988.1 KB) | EPUB
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Article
Proteomic characterisation of drug metabolising enzymes and drug transporters in pig liver
Yasmine Elmorsi, Hajar Al Feteisi, Zubida M. Al-Majdoub, Jill Barber, Amin Rostami-Hodjegan & Brahim Achour
Pages: 1208-1219
Published online: 13 May 2020
AbstractforProteomic characterisation of drug metabolising enzymes and drug transporters in pig liver | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
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Article
Prediction of pharmacokinetic clearance and potential Drug-Drug interactions for omeprazole in the horse using in vitro systems
Khaled A. Shibany, Stefanie L. Pratt, Mohammed Aldurdunji, Sabine Totemeyer & Stuart W. Paine
Pages: 1220-1227
Published online: 20 May 2020
AbstractforPrediction of pharmacokinetic clearance and potential Drug-Drug interactions for omeprazole in the horse using in vitro systems | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Article
The use of inactivated brain homogenate to determine the in vitro fraction unbound in brain for unstable compounds
Ramakrishna Nirogi, Parusharamulu Molgara, Gopinadh Bhyrapuneni, Arunkumar Manoharan, Nagasurya Prakash Padala & Veera Raghava Chowdary Palacharla
Pages: 1228-1235
Published online: 05 Jun 2020
AbstractforThe use of inactivated brain homogenate to determine the in vitro fraction unbound in brain for unstable compounds | Full Text | References | PDF (1.3 MB) | EPUB
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Animal Pharmacokinetics and Metabolism

Article
Pharmacokinetics and tissue disposition of enrofloxacin in rainbow trout after different routes of administration
Natalia Urzúa, María Jimena Messina, Guillermo Prieto, Carlos Lüders & Carlos Errecalde
Pages: 1236-1241
Published online: 06 Apr 2020
AbstractforPharmacokinetics and tissue disposition of enrofloxacin in rainbow trout after different routes of administration | Full Text | References | PDF (801 KB) | EPUB | Supplemental
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Article
Pharmacokinetics of trastuzumab deruxtecan (T-DXd), a novel anti-HER2 antibody-drug conjugate, in HER2-positive tumour-bearing mice
Hiromi Okamoto, Masataka Oitate, Katsunobu Hagihara, Hideyuki Shiozawa, Yoshitake Furuta, Yusuke Ogitani & Hiroshi Kuga
Pages: 1242-1250
Published online: 22 Apr 2020
AbstractforPharmacokinetics of trastuzumab deruxtecan (T-DXd), a novel anti-HER2 antibody-drug conjugate, in HER2-positive tumour-bearing mice | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Article
Differential changes in the pharmacokinetics of doxorubicin in diethylnitrosamine-induced hepatocarcinoma model rats
Jie Pan, Yuan Lu, Shuai Zhang, Yueting Li, Jia Sun, Hua Chunhua Liu, Zipeng Gong, Jing Huang, Chuang Cao, Yonglin Wang, Yongjun Li & Ting Liu
Pages: 1251-1257
Published online: 13 May 2020
AbstractforDifferential changes in the pharmacokinetics of doxorubicin in diethylnitrosamine-induced hepatocarcinoma model rats | Full Text | References | PDF (1.6 MB) | EPUB
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Xenobiotic transporters

Article
Is aspirin a substrate of MDR1/P-glycoprotein?
Renu Singh, Tanvi Naik, Anuja Nigam, Sagnik Chatterjee, Prabhakar Rajanna, Hong Shen & Ramaswamy Iyer
Pages: 1258-1264
Published online: 29 Apr 2020
AbstractforIs aspirin a substrate of MDR1/P-glycoprotein? | Full Text | References | PDF (889.8 KB) | EPUB | Supplemental
  • 271 Views
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Expression of Concern

Correction
Expression of Concern
Page: 1265
Published online: 07 Apr 2020
CitationforExpression of Concern | Full Text | PDF (69.7 KB) | EPUB
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