Xenobiotica, Volume 50, Issue 8 (2020)

Browse this journal
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Xenobiotica, Volume 50, Issue 8 (2020)

See all volumes and issues
Vol 54, 2024 Vol 53, 2023 Vol 52, 2022 Vol 51, 2021 Volume 50, 2020 Vol 49, 2019 Vol 48, 2018 Vol 47, 2017 Vol 46, 2016 Vol 45, 2015 Vol 44, 2014 Vol 43, 2013 Vol 42, 2012 Vol 41, 2011 Vol 40, 2010 Vol 39, 2009 Vol 38, 2008 Vol 37, 2007 Vol 36, 2006 Vol 35, 2005 Vol 34, 2004 Vol 33, 2003 Vol 32, 2002 Vol 31, 2001 Vol 30, 2000 Vol 29, 1999 Vol 28, 1998 Vol 27, 1997 Vol 26, 1996 Vol 25, 1995 Vol 24, 1994 Vol 23, 1993 Vol 22, 1992 Vol 21, 1991 Vol 20, 1990 Vol 19, 1989 Vol 18, 1988 Vol 17, 1987 Vol 16, 1986 Vol 15, 1985 Vol 14, 1984 Vol 13, 1983 Vol 12, 1982 Vol 11, 1981 Vol 10, 1980 Vol 9, 1979 Vol 8, 1978 Vol 7, 1977 Vol 6, 1976 Vol 5, 1975 Vol 4, 1974 Vol 3, 1973 Vol 2, 1972 Vol 1, 1971
Download citations Download PDFs Download issue

General Xenobiochemistry

Article
Quantitative evaluation of hepatic and intestinal induction of CYP3A in clinical practice
Haruka Tsutsui, Motohiro Kato, Shino Kuramoto, Nobuo Sekiguchi, Hidetoshi Shindoh & Kazuhisa Ozeki
Pages: 875-884
Published online: 07 Jan 2020
AbstractforQuantitative evaluation of hepatic and intestinal induction of CYP3A in clinical practice | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 479 Views
  • 0 CrossRef citations
  • 0Altmetric
Article
In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species
Risto O. Juvonen, Olli Pentikäinen, Juhani Huuskonen, Juri Timonen, Olli Kärkkäinen, Aki Heikkinen, Muluneh Fashe & Hannu Raunio
Pages: 885-893
Published online: 08 Jan 2020
AbstractforIn vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 258 Views
  • 1 CrossRef citations
  • 0Altmetric
Article
Metabonomics analysis of liver in rats administered with chronic low-dose acrylamide
Yanli Liu, Ruijuan Wang, Kai Zheng, Youwei Xin, Siqi Jia & Xiujuan Zhao
Pages: 894-905
Published online: 20 Jan 2020
AbstractforMetabonomics analysis of liver in rats administered with chronic low-dose acrylamide | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 303 Views
  • 15 CrossRef citations
  • 0Altmetric
Article
Wogonin glucuronidation in liver and intestinal microsomes of humans, monkeys, dogs, rats, and mice
Nobumitsu Hanioka, Takashi Isobe, Toshiko Tanaka-Kagawa & Susumu Ohkawara
Pages: 906-912
Published online: 12 Feb 2020
AbstractforWogonin glucuronidation in liver and intestinal microsomes of humans, monkeys, dogs, rats, and mice | Full Text | References | PDF (1.2 MB) | EPUB
  • 198 Views
  • 8 CrossRef citations
  • 0Altmetric
Article
In vitro effect of pachymic acid on the activity of Cytochrome P450 enzymes
Baodong Ding, Xiaofei Ji, Xueming Sun, Tongtong Zhang & Suping Mu
Pages: 913-918
Published online: 12 Feb 2020
AbstractforIn vitro effect of pachymic acid on the activity of Cytochrome P450 enzymes | Full Text | References | PDF (944.8 KB) | EPUB
  • 154 Views
  • 7 CrossRef citations
  • 0Altmetric
Article
Bioactivation of diclofenac in human hepatocytes and the proposed human hepatic proteins modified by reactive metabolites
Kazuko Inoue, Hitoshi Mizuo, Tomomi Ishida, Takafumi Komori & Kazutomi Kusano
Pages: 919-928
Published online: 18 Feb 2020
AbstractforBioactivation of diclofenac in human hepatocytes and the proposed human hepatic proteins modified by reactive metabolites | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 412 Views
  • 3 CrossRef citations
  • 0Altmetric
Article
CYP2C19 and CYP3A4 activity and ADP-induced platelet reactivity in prasugrel- or ticagrelor-treated STEMI patients: monocentric study in PRAGUE-18 trial participants
J. Máchal, O. Hlinomaz, K. Kostolanská, O. Peš, A. Máchalová, Z. Šplíchal, Z. Mot'ovská & J. Juřica
Pages: 929-938
Published online: 30 Mar 2020
AbstractforCYP2C19 and CYP3A4 activity and ADP-induced platelet reactivity in prasugrel- or ticagrelor-treated STEMI patients: monocentric study in PRAGUE-18 trial participants | Full Text | References | PDF (1.7 MB) | EPUB
  • 235 Views
  • 3 CrossRef citations
  • 0Altmetric
Article
Osthole inhibited the activity of CYP2C9 in human liver microsomes and influenced indomethacin pharmacokinetics in rats
Hui He, Yuandong Zhang, Dezhang Zhao, Junhao Jiang, Baogang Xie, Limei Ma, Xueqing Liu & Chao Yu
Pages: 939-946
Published online: 02 Apr 2020
AbstractforOsthole inhibited the activity of CYP2C9 in human liver microsomes and influenced indomethacin pharmacokinetics in rats | Full Text | References | PDF (1 MB) | EPUB
  • 157 Views
  • 7 CrossRef citations
  • 0Altmetric

Clinical Pharmacokinetics and Metabolism

Article
Absorption, distribution, metabolism, and excretion of cenerimod, a selective S1P1 receptor modulator in healthy subjects
Marie-Laure Boof, Jan Jaap van Lier, Stephen English, Hartmut Fischer, Mike Ufer & Jasper Dingemanse
Pages: 947-956
Published online: 09 Mar 2020
AbstractforAbsorption, distribution, metabolism, and excretion of cenerimod, a selective S1P1 receptor modulator in healthy subjects | Full Text | References | PDF (1.6 MB) | EPUB
  • 251 Views
  • 5 CrossRef citations
  • 0Altmetric

Animal Pharmacokinetics and Metabolism

Article
Withanolide a penetrates brain via intra-nasal administration and exerts neuroprotection in cerebral ischemia reperfusion injury in mice
Sumedha Mukherjee, Gaurav Kumar & Ranjana Patnaik
Pages: 957-966
Published online: 13 Jan 2020
AbstractforWithanolide a penetrates brain via intra-nasal administration and exerts neuroprotection in cerebral ischemia reperfusion injury in mice | Full Text | References | PDF (2.5 MB) | EPUB
  • 231 Views
  • 12 CrossRef citations
  • 0Altmetric
Article
Absorption, distribution, metabolism and excretion of darolutamide (a novel non-steroidal androgen receptor antagonist) in rats
Päivi Taavitsainen, Hille Gieschen, Timo Korjamo, Marja Kähkönen, Chira Malmström, Olaf Prien, Michael Niehues, Steffen Sandmann, Wiebke Janssen & Mikko Koskinen
Pages: 967-979
Published online: 06 Feb 2020
AbstractforAbsorption, distribution, metabolism and excretion of darolutamide (a novel non-steroidal androgen receptor antagonist) in rats | Full Text | References | PDF (1.8 MB) | EPUB
  • 778 Views
  • 9 CrossRef citations
  • 0Altmetric
Article
Pharmacokinetics and tissue distribution in rats of a novel anticancer platinum compound LLC-1903
Yingxue Li, Fanzhuo Meng, Zhijian Chen, Fuguo Han, Donglin He, Yanli Hao, Anli Gao, Jing Jiang, Zhao Wang, Weiping Liu & Qingfei Liu
Pages: 980-987
Published online: 19 Feb 2020
AbstractforPharmacokinetics and tissue distribution in rats of a novel anticancer platinum compound LLC-1903 | Full Text | References | PDF (935 KB) | EPUB
  • 174 Views
  • 1 CrossRef citations
  • 0Altmetric

Xenobiotic Transporters

Article
Modulation of ABCG2 surface expression by Rab5 and Rab21 to overcome multidrug resistance in cancer cells
Maryam Yousaf & Moazzam Ali
Pages: 988-996
Published online: 22 Jan 2020
AbstractforModulation of ABCG2 surface expression by Rab5 and Rab21 to overcome multidrug resistance in cancer cells | Full Text | References | PDF (1.9 MB) | EPUB
  • 223 Views
  • 9 CrossRef citations
  • 0Altmetric
Article
Metabolism and disposition of corylifol A from Psoralea corylifolia: metabolite mapping, isozyme contribution, species differences and identification of efflux transporters for corylifol A-O-glucuronide in HeLa1A1 cells
Yang Li, Jinjin Xu, Chunxia Xu, Zifei Qin, Shishi Li, Liufang Hu, Zhihong Yao, Frank J. Gonzalez & Xinsheng Yao
Pages: 997-1008
Published online: 01 Apr 2020
AbstractforMetabolism and disposition of corylifol A from Psoralea corylifolia: metabolite mapping, isozyme contribution, species differences and identification of efflux transporters for corylifol A-O-glucuronide in HeLa1A1 cells | Full Text | References | PDF (2 MB) | EPUB | Supplemental
  • 743 Views
  • 7 CrossRef citations
  • 0Altmetric

Correction Statement

Correction
Correction
Page: 1009
Published online: 25 Feb 2020
CitationforCorrection | Full Text | PDF (93.2 KB) | EPUB
  • 474 Views
  • 0 CrossRef citations
  • 0Altmetric
Free Access

Explore articles